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Protein
Submitted name:

Acetylcholine receptor delta subunit

Gene
N/A
Organism
Torpedo marmorata (Marbled electric ray)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionIon channel, Ligand-gated ion channelSAAS annotation, ReceptorSAAS annotationImported
Biological processIon transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Acetylcholine receptor delta subunitImported
OrganismiTorpedo marmorata (Marbled electric ray)Imported
Taxonomic identifieri7788 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataChondrichthyesElasmobranchiiBatoideaTorpediniformesTorpedinidaeTorpedo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei247 – 270HelicalSequence analysisAdd BLAST24
Transmembranei282 – 300HelicalSequence analysisAdd BLAST19
Transmembranei312 – 333HelicalSequence analysisAdd BLAST22
Transmembranei477 – 497HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Cell junction, Cell membraneSAAS annotation, Membrane, Postsynaptic cell membraneSAAS annotation, Synapse

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_500427961222 – 522Sequence analysisAdd BLAST501

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi151 ↔ 165Combined sources

Keywords - PTMi

Disulfide bondSAAS annotation

Interactioni

Protein-protein interaction databases

ComplexPortaliCPX-2635 Acetylcholine receptor, alpha1-beta1-gamma-delta

Structurei

3D structure databases

ProteinModelPortaliQ6S3H8
SMRiQ6S3H8
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ6S3H8

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini25 – 246Neur_chan_LBDInterPro annotationAdd BLAST222
Domaini254 – 494Neur_chan_membInterPro annotationAdd BLAST241

Sequence similaritiesi

Belongs to the ligand-gated ion channel (TC 1.A.9) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

HOVERGENiHBG003756

Family and domain databases

Gene3Di2.70.170.10, 1 hit
InterProiView protein in InterPro
IPR006202 Neur_chan_lig-bd
IPR036734 Neur_chan_lig-bd_sf
IPR006201 Neur_channel
IPR036719 Neuro-gated_channel_TM_sf
IPR006029 Neurotrans-gated_channel_TM
IPR018000 Neurotransmitter_ion_chnl_CS
IPR002394 Nicotinic_acetylcholine_rcpt
PANTHERiPTHR18945 PTHR18945, 1 hit
PfamiView protein in Pfam
PF02931 Neur_chan_LBD, 1 hit
PF02932 Neur_chan_memb, 1 hit
PRINTSiPR00254 NICOTINICR
PR00252 NRIONCHANNEL
SUPFAMiSSF63712 SSF63712, 1 hit
SSF90112 SSF90112, 1 hit
TIGRFAMsiTIGR00860 LIC, 1 hit
PROSITEiView protein in PROSITE
PS00236 NEUROTR_ION_CHANNEL, 1 hit

Sequencei

Sequence statusi: Complete.

Q6S3H8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGNIHFVYLL ISCLYYSGCS GVNEEERLIN DLLIVNKYNK HVRPVKHNNE
60 70 80 90 100
VVNIALSLTL SNLISLKETD ETLTTNVWMD HAWYDHRLTW NASEYSDISI
110 120 130 140 150
LRLRPELIWI PDIVLQNNND GQYNVAYFCN VLVRPNGYVT WLPPAIFRSS
160 170 180 190 200
CPINVLYFPF DWQNCSLKFT ALNYNANEIS MDLMTDTIDG KDYPIEWIII
210 220 230 240 250
DPEAFTENGE WEIIHKPAKK NIYGDKFPNG TNYQDVTFYL IIRRKPLFYV
260 270 280 290 300
INFITPCVLI SFLAALAFYL PAESGEKMST AICVLLAQAV FLLLTSQRLP
310 320 330 340 350
ETALAVPLIG KYLMFIMSLV TGVVVNCGIV LNFHFRTPST HVLSTRVKQI
360 370 380 390 400
FLEKLPRILH MSRVDEIEQP DWQNDLKLRR SSSVGYISKA QEYFNIKSRS
410 420 430 440 450
ELMFEKQSER HGLVPRVTPR IGFGNNNENI AASDQLHDEI KSGIDSTNYI
460 470 480 490 500
VKQIKEKNAY DEEVGNWNLV GQTIDRLSMF IITPVMVLGT IFIFVMGNFN
510 520
RPPAKPFEGD PFDYSSDHPR CA
Length:522
Mass (Da):59,959
Last modified:July 5, 2004 - v1
Checksum:i6CE58EB60719E31D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY472105 mRNA Translation: AAR29363.1

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY472105 mRNA Translation: AAR29363.1

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2BG9electron microscopy4.00C22-505[»]
4AQ5electron microscopy6.20C1-522[»]
4AQ9electron microscopy6.20C1-522[»]
4BOGelectron microscopy50.001/C/H/M/R/W1-522[»]
4BOIelectron microscopy41.00C1-522[»]
4BONelectron microscopy40.00C1-522[»]
4BOOelectron microscopy42.00C1-522[»]
4BORelectron microscopy42.00C1-522[»]
4BOTelectron microscopy42.00C1-522[»]
ProteinModelPortaliQ6S3H8
SMRiQ6S3H8
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

ComplexPortaliCPX-2635 Acetylcholine receptor, alpha1-beta1-gamma-delta

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG003756

Miscellaneous databases

EvolutionaryTraceiQ6S3H8

Family and domain databases

Gene3Di2.70.170.10, 1 hit
InterProiView protein in InterPro
IPR006202 Neur_chan_lig-bd
IPR036734 Neur_chan_lig-bd_sf
IPR006201 Neur_channel
IPR036719 Neuro-gated_channel_TM_sf
IPR006029 Neurotrans-gated_channel_TM
IPR018000 Neurotransmitter_ion_chnl_CS
IPR002394 Nicotinic_acetylcholine_rcpt
PANTHERiPTHR18945 PTHR18945, 1 hit
PfamiView protein in Pfam
PF02931 Neur_chan_LBD, 1 hit
PF02932 Neur_chan_memb, 1 hit
PRINTSiPR00254 NICOTINICR
PR00252 NRIONCHANNEL
SUPFAMiSSF63712 SSF63712, 1 hit
SSF90112 SSF90112, 1 hit
TIGRFAMsiTIGR00860 LIC, 1 hit
PROSITEiView protein in PROSITE
PS00236 NEUROTR_ION_CHANNEL, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ6S3H8_TORMA
AccessioniPrimary (citable) accession number: Q6S3H8
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: October 10, 2018
This is version 100 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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