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Protein

Poly(A) polymerase catalytic subunit

Gene

PAPL

Organism
Rabbitpox virus (strain Utrecht) (RPV)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Polymerase that creates the 3'-poly(A) tail of mRNA's.

Catalytic activityi

ATP + RNA(n) = diphosphate + RNA(n+1).

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei202By similarity1
Active sitei204By similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferase
Biological processmRNA processing, Transcription
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Poly(A) polymerase catalytic subunit (EC:2.7.7.19)
Alternative name(s):
Poly(A) polymerase large subunit
Short name:
PAP-L
Gene namesi
Name:PAPL
Ordered Locus Names:RPXV046
OrganismiRabbitpox virus (strain Utrecht) (RPV)
Taxonomic identifieri45417 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stagePoxviridaeChordopoxvirinaeOrthopoxvirusVaccinia virus
Virus hostiOryctolagus cuniculus (Rabbit) [TaxID: 9986]

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003089381 – 479Poly(A) polymerase catalytic subunitAdd BLAST479

Interactioni

Subunit structurei

Heterodimer of a large (catalytic) subunit and a small (regulatory) subunit.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ6RZP5
SMRiQ6RZP5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di1.20.1270.320, 1 hit
3.30.460.60, 1 hit
InterProiView protein in InterPro
IPR037265 PolyA_pol_cat_sf
IPR024231 Pox_polyA_pol_nucTrfase
IPR038419 Pox_polyA_pol_nucTrfase_sf
IPR004976 Poxviridae_polyA_pol_cat
IPR024397 Poxvirus_polyA_pol_cat_C
IPR024398 Poxvirus_polyA_pol_cat_N
IPR038337 Poxvirus_polyA_pol_cat_N_sf
PfamiView protein in Pfam
PF03296 Pox_polyA_pol, 1 hit
PF12629 Pox_polyA_pol_C, 1 hit
PF12630 Pox_polyA_pol_N, 1 hit
PIRSFiPIRSF015693 VAC-48L_nuct, 1 hit
SUPFAMiSSF160957 SSF160957, 1 hit

Sequencei

Sequence statusi: Complete.

Q6RZP5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNRNPDQNTL PNITLKIIET YLGRVPSVNE YHMLKLQARN IQKITVFNKD
60 70 80 90 100
IFVSLVKKNK KRFFSDVDTS ASEIKDRILS YFSKQTQTYN IGKLFTIIEL
110 120 130 140 150
QSVLVTTYTD ILGVLTIKAP NVISSKISYN VTSMEELARD MLNSMNVAVI
160 170 180 190 200
DKAKVMGRHN VSSLVKNVNK LMEEYLRRHN KSCICYGSYS LYLINPNIRY
210 220 230 240 250
GDIDILQTNS RTFLIDLAFL IKFITGNNII LSKIPYLRNY MVIKDENDNH
260 270 280 290 300
IIDSFNIRQD TMNVVPKIFI DNIYIVDPTF QLLNMIKMFS QIDRLEDLSK
310 320 330 340 350
DPEKFNARMA TMLEYVRYTH GIVFDGKRNN MPMKCIIDEN NRIVTVTTKD
360 370 380 390 400
YFSFKKCLVY LDENVLSSDI LDLNADTSCD FESVTNSVYL IHDNIMYTYF
410 420 430 440 450
SNTILLSDKG KVHEISARGL CAHILLYQML TSGEYKQCLS DLLNSMMNRD
460 470
KIPIYSHTER DKKPGRHGFI NIEKDIIVF
Length:479
Mass (Da):55,532
Last modified:July 5, 2004 - v1
Checksum:i79FE3A151EC51A77
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY484669 Genomic DNA Translation: AAS49759.1

Similar proteinsi

Entry informationi

Entry nameiPAP1_RABPU
AccessioniPrimary (citable) accession number: Q6RZP5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: July 5, 2004
Last modified: March 28, 2018
This is version 40 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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