UniProtKB - Q6RVA0 (Q6RVA0_HUMAN)
Protein
Submitted name:
p-glycoprotein
Gene
MDR1
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- ATP binding Source: InterPro
Keywordsi
Biological process | TransportARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: p-glycoproteinImported |
Gene namesi | Name:MDR1Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Subcellular locationi
Other locations
- integral component of membrane Source: UniProtKB-KW
Keywords - Cellular componenti
MembraneFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 39 – 154 | ABC transporterInterPro annotationAdd BLAST | 116 |
Keywords - Domaini
Transmembrane, Transmembrane helixARBA annotationFamily and domain databases
Gene3Di | 1.20.1560.10, 1 hit |
InterProi | View protein in InterPro IPR036640, ABC1_TM_sf IPR003439, ABC_transporter-like IPR030258, MDR1 IPR027417, P-loop_NTPase IPR039421, Type_1_exporter |
PANTHERi | PTHR24221, PTHR24221, 1 hit PTHR24221:SF251, PTHR24221:SF251, 1 hit |
Pfami | View protein in Pfam PF00005, ABC_tran, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
i Sequence
Sequence statusi: Fragment.
Q6RVA0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
KPSIDSYSKS GHKPDNIKGN LEFRNVHFSY PSRKEVKILK GLNLKVQSGQ
60 70 80 90 100
TVALVGNSGC GKSTTVQLMQ RLYDPTEGML PFQLQMYESH TYFLFQVSVD
110 120 130 140 150
GQDIRTINVR FLREIIGVVS QEPVLFATTI AENIRYGREN VTMDEIEKAV
160
KEANAYDFIM KLPH
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 | |
Non-terminal residuei | 164 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY490254 Genomic DNA Translation: AAR99172.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY490254 Genomic DNA Translation: AAR99172.1 |
3D structure databases
SMRi | Q6RVA0 |
ModBasei | Search... |
Proteomic databases
MaxQBi | Q6RVA0 |
PeptideAtlasi | Q6RVA0 |
Family and domain databases
Gene3Di | 1.20.1560.10, 1 hit |
InterProi | View protein in InterPro IPR036640, ABC1_TM_sf IPR003439, ABC_transporter-like IPR030258, MDR1 IPR027417, P-loop_NTPase IPR039421, Type_1_exporter |
PANTHERi | PTHR24221, PTHR24221, 1 hit PTHR24221:SF251, PTHR24221:SF251, 1 hit |
Pfami | View protein in Pfam PF00005, ABC_tran, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q6RVA0_HUMAN | |
Accessioni | Q6RVA0Primary (citable) accession number: Q6RVA0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 5, 2004 |
Last sequence update: | July 5, 2004 | |
Last modified: | April 7, 2021 | |
This is version 42 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |