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Entry version 102 (12 Aug 2020)
Sequence version 1 (05 Jul 2004)
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Protein

Reticulon-3

Gene

Rtn3

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. Induces the formation of endoplasmic reticulum tubules (By similarity).By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processApoptosis, ER-Golgi transport, Transport

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-RNO-8849932, Synaptic adhesion-like molecules

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Reticulon-3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Rtn3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRattus norvegicus (Rat)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10116 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002494 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Rat genome database

More...
RGDi
620988, Rtn3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini2 – 771CytoplasmicSequence analysisAdd BLAST770
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a region that is buried within a membrane, but does not cross it.<p><a href='/help/intramem' target='_top'>More...</a></p>Intramembranei772 – 795HelicalSequence analysisAdd BLAST24
Topological domaini796 – 852CytoplasmicSequence analysisAdd BLAST57
Intramembranei853 – 875HelicalSequence analysisAdd BLAST23
Topological domaini876 – 879CytoplasmicSequence analysis4
Intramembranei880 – 902HelicalSequence analysisAdd BLAST23
Topological domaini903 – 940CytoplasmicSequence analysisAdd BLAST38

Keywords - Cellular componenti

Endoplasmic reticulum, Golgi apparatus, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedBy similarity
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002805412 – 940Reticulon-3Add BLAST939

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylalanineBy similarity1
Modified residuei31PhosphoserineCombined sources1
Modified residuei196PhosphoserineBy similarity1
Modified residuei204PhosphoserineBy similarity1
Modified residuei209PhosphoserineCombined sources1
Modified residuei212PhosphoserineCombined sources1
Modified residuei249PhosphoserineCombined sources1
Modified residuei282PhosphoserineBy similarity1
Modified residuei508PhosphoserineBy similarity1
Modified residuei572PhosphothreonineCombined sources1
Modified residuei575PhosphoserineCombined sources1
Modified residuei576PhosphoserineCombined sources1
Modified residuei652PhosphoserineBy similarity1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q6RJR6

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q6RJR6

PRoteomics IDEntifications database

More...
PRIDEi
Q6RJR6

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q6RJR6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q6RJR6

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q6RJR6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Present in olfactory bulb, olfactory epithelium and retina (at protein level).1 Publication

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

In the optic nerve, expressed more abundantly in the embryo than in the adult.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSRNOG00000021202, Expressed in brain and 22 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q6RJR6, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q6RJR6, RN

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer.

Interacts with RTN4.

Isoform 2 interacts with BACE1, BACE2, BCL2 and FADD.

Interacts with ATL2.

Interacts with TMEM33 (By similarity).

Interacts with ATL1 (PubMed:19665976).

Interacts with ZFYVE27 and with KIF5A in a ZFYVE27-dependent manner (By similarity).

By similarity1 Publication

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
250879, 1 interactor

Protein interaction database and analysis system

More...
IntActi
Q6RJR6, 1 interactor

STRING: functional protein association networks

More...
STRINGi
10116.ENSRNOP00000028785

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q6RJR6

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini752 – 940ReticulonPROSITE-ProRule annotationAdd BLAST189

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni895 – 940Interaction with FADDBy similarityAdd BLAST46
Regioni908 – 910Interaction with BACE1By similarity3

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1792, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000157482

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_011704_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q6RJR6

KEGG Orthology (KO)

More...
KOi
K20723

Identification of Orthologs from Complete Genome Data

More...
OMAi
KSKYSEQ

Database of Orthologous Groups

More...
OrthoDBi
423549at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q6RJR6

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003388, Reticulon

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02453, Reticulon, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50845, RETICULON, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q6RJR6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAESSAATQS PSVSSSSSGA EPSTLGGGGG SPGACPALGA KSCGSSCAVG
60 70 80 90 100
LSSLCSDEPP SKIMTSSFLS SSEIYNPDPT TPLGSETLGS HLVAKDGKDP
110 120 130 140 150
LVLLDKKTLD SPQGTNKDRV DTPVSLAADI PCSHPSIPDS FPEQPTFLSK
160 170 180 190 200
ETDPTEEWVV KNQEPKNPSE VPSGEDRSAL DLGQRKAEHI CTHSLSPSEP
210 220 230 240 250
AVASVEKDSP ESPFEVIIDK ATFDREFKDL YKESTDDLGG WAAHGDRESP
260 270 280 290 300
ADLLEMNDKV FPLRNKEAGR YPSSALLGRQ FSHTTAALEE VSRCVNDMHN
310 320 330 340 350
FTNEILTWDL DPQAKQQADK SPCTTESTGL DRSEHRSEIP VINLKTSPQQ
360 370 380 390 400
KMPVCSFNGS TPITRSTGDW TETFTEGKPV KGYLSSTKEA GGKGVPDSSQ
410 420 430 440 450
PISGSGAATV EVTLPDLRGT WPNSVLGEVT EVDSSGESDD TVIEDTTENP
460 470 480 490 500
SVKNNKVLPE KSDSLPSAAV KTSERENKET TSHETVRSEM YENSEQQQAH
510 520 530 540 550
AETPTQRSLE GQMSPQVPNM LNEVIPENLA MTDTTRVCSA APPSVLSETG
560 570 580 590 600
FSLTVPASAK SESLLGKNVE DTDGSSPEDL MAALTGTEEK GTVDKEKGDV
610 620 630 640 650
LEAVLEKIAN VKNTLPVELL HENKLSSSET KNTKSKYSEH SRETNGGAPK
660 670 680 690 700
VSSDLEQEQL TIRAIKELGA KQVQAERMSP GGKLKRTFDP QSGPQNSSDI
710 720 730 740 750
LEHTDITTGS DLGIPKKPTI IKDTRIDSIS SLTKTETVNK HVLARLLSDF
760 770 780 790 800
PVHDLIFWRD VKKTGFVFGT TLIMLLSLAA FSVISVVSYL ILALLSVTIS
810 820 830 840 850
FRVYKSVIQA VQKSEEGHPF KAYLDVDITL SSEAFHSYMN AAMVHVNKAL
860 870 880 890 900
KLIIRLFLVE DLVDSLKLAV FMWLMTYVGA VFNGITLLIL AELLVFSVPI
910 920 930 940
VYEKYKTQID HYVGIARDQT KSIVEKIQAK LPGIAKKKAE
Length:940
Mass (Da):101,517
Last modified:July 5, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i701B0CF84473D36B
GO
Isoform 2 (identifier: Q6RJR6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     49-751: Missing.

Show »
Length:237
Mass (Da):25,431
Checksum:iE5E372302F8A4735
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0H2UHX1A0A0H2UHX1_RAT
Reticulon
Rtn3
261Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti26Missing in AAP47276 (PubMed:12832288).Curated1
Sequence conflicti26Missing in AAL35353 (PubMed:15946766).Curated1
Sequence conflicti26Missing in AAL35354 (PubMed:15946766).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_02377149 – 751Missing in isoform 2. 3 PublicationsAdd BLAST703

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY164698 mRNA Translation: AAP47276.1
AY496443 mRNA Translation: AAR89918.1
AF442357 mRNA Translation: AAL35353.1
AF442358 mRNA Translation: AAL35354.1
BC062068 mRNA Translation: AAH62068.1
BC107448 mRNA Translation: AAI07449.1

NCBI Reference Sequences

More...
RefSeqi
NP_001009953.2, NM_001009953.3 [Q6RJR6-2]
NP_543185.2, NM_080909.3 [Q6RJR6-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSRNOT00000028785; ENSRNOP00000028785; ENSRNOG00000021202 [Q6RJR6-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
140945

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
rno:140945

UCSC genome browser

More...
UCSCi
RGD:620988, rat [Q6RJR6-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY164698 mRNA Translation: AAP47276.1
AY496443 mRNA Translation: AAR89918.1
AF442357 mRNA Translation: AAL35353.1
AF442358 mRNA Translation: AAL35354.1
BC062068 mRNA Translation: AAH62068.1
BC107448 mRNA Translation: AAI07449.1
RefSeqiNP_001009953.2, NM_001009953.3 [Q6RJR6-2]
NP_543185.2, NM_080909.3 [Q6RJR6-1]

3D structure databases

SMRiQ6RJR6
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi250879, 1 interactor
IntActiQ6RJR6, 1 interactor
STRINGi10116.ENSRNOP00000028785

PTM databases

iPTMnetiQ6RJR6
PhosphoSitePlusiQ6RJR6
SwissPalmiQ6RJR6

Proteomic databases

jPOSTiQ6RJR6
PaxDbiQ6RJR6
PRIDEiQ6RJR6

Genome annotation databases

EnsembliENSRNOT00000028785; ENSRNOP00000028785; ENSRNOG00000021202 [Q6RJR6-1]
GeneIDi140945
KEGGirno:140945
UCSCiRGD:620988, rat [Q6RJR6-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
10313
RGDi620988, Rtn3

Phylogenomic databases

eggNOGiKOG1792, Eukaryota
GeneTreeiENSGT00940000157482
HOGENOMiCLU_011704_0_0_1
InParanoidiQ6RJR6
KOiK20723
OMAiKSKYSEQ
OrthoDBi423549at2759
PhylomeDBiQ6RJR6

Enzyme and pathway databases

ReactomeiR-RNO-8849932, Synaptic adhesion-like molecules

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q6RJR6

Gene expression databases

BgeeiENSRNOG00000021202, Expressed in brain and 22 other tissues
ExpressionAtlasiQ6RJR6, baseline and differential
GenevisibleiQ6RJR6, RN

Family and domain databases

InterProiView protein in InterPro
IPR003388, Reticulon
PfamiView protein in Pfam
PF02453, Reticulon, 1 hit
PROSITEiView protein in PROSITE
PS50845, RETICULON, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRTN3_RAT
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6RJR6
Secondary accession number(s): Q6P6R3, Q8VBU0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: July 5, 2004
Last modified: August 12, 2020
This is version 102 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome
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