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Protein

Uncharacterized protein ORF22

Gene

ORF22

Organism
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Uncharacterized protein ORF22
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:ORF22
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiOstreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri654903 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiVirusesdsDNA viruses, no RNA stageHerpesviralesMalacoherpesviridaeOstreavirus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section only exists in viral entries and indicates the host(s) either as a specific organism or taxonomic group of organisms that are susceptible to be infected by a virus.<p><a href='/help/virus_host' target='_top'>More...</a></p>Virus hostiCrassostrea gigas (Pacific oyster) (Crassostrea angulata) [TaxID: 29159]
Pecten maximus (King scallop) (Pilgrim's clam) [TaxID: 6579]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000007021 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 63CytoplasmicSequence analysisAdd BLAST63
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei64 – 86HelicalSequence analysisAdd BLAST23
Topological domaini87 – 1632ExtracellularSequence analysisAdd BLAST1546

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Host membrane, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003850531 – 1632Uncharacterized protein ORF22Add BLAST1632

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi149N-linked (GlcNAc...) asparagine; by hostSequence analysis1
Glycosylationi274N-linked (GlcNAc...) asparagine; by hostSequence analysis1
Glycosylationi654N-linked (GlcNAc...) asparagine; by hostSequence analysis1
Glycosylationi719N-linked (GlcNAc...) asparagine; by hostSequence analysis1
Glycosylationi797N-linked (GlcNAc...) asparagine; by hostSequence analysis1
Glycosylationi1012N-linked (GlcNAc...) asparagine; by hostSequence analysis1
Glycosylationi1031N-linked (GlcNAc...) asparagine; by hostSequence analysis1
Glycosylationi1261N-linked (GlcNAc...) asparagine; by hostSequence analysis1
Glycosylationi1339N-linked (GlcNAc...) asparagine; by hostSequence analysis1
Glycosylationi1511N-linked (GlcNAc...) asparagine; by hostSequence analysis1
Glycosylationi1546N-linked (GlcNAc...) asparagine; by hostSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
Q6R7K1

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi882 – 886Poly-Lys5
Compositional biasi1588 – 1625Asp-richAdd BLAST38

Keywords - Domaini

Transmembrane, Transmembrane helix

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q6R7K1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSNNKQTAAP AATSNEKAEN GAEKEAIEKF VEVVRNTPEL QGEMFFDGCI
60 70 80 90 100
IAMTKDAFKG KYRVFYGNGL HTSIMFGAGT AALDLMTPGS FLPPFPQRLI
110 120 130 140 150
KSREGSAPTM EATDPMMSRV IILMNGECLD VNSELINRPK TMGDDAISNL
160 170 180 190 200
TDDLNNITPK EGEATVKEWD SLPGGELRYL SKANKPDETY MKDLIEKYFE
210 220 230 240 250
KAICHNGKKV EDYVFFLVAN PIAMVSLARK GFMSNVNMHN YESFENNIVI
260 270 280 290 300
PADDDELYFG DHTFKVAVNN ERLNTSSVAN CNAYVRPFFH GCNGFYQGRN
310 320 330 340 350
KRIYPESHDL YRRDYIKDYN TDYKSLCYSR KTENVMPVCD FISSTAATLV
360 370 380 390 400
LQKFPLNYVI EHKFTTEDDD YKTKMAMSVK LDLIKEIAIK NRYRPNVFDD
410 420 430 440 450
NFHVSQDRIY ATKYQGHLER NTISPNALHT YKTGGKLGIA GELMEGEKMS
460 470 480 490 500
QWVHTDIASK FTSMENFNKN GGDEAALCDD EEKELGFGKM YVTSRLSSVF
510 520 530 540 550
DFKSIFNANR MTTQHELSSQ LGDTDTKKEQ KEKRSKQGGS KLFNYKIKSA
560 570 580 590 600
FNPVFNSLKS PAQKILFNMC GDRTLFKSVM EDALFLLRDE IFLEDKLVMT
610 620 630 640 650
HPAFAESENP NHCQYCKCSF NNGMAGVENK DFCFCYLILR TMCALSAREP
660 670 680 690 700
TQFNITNLWD KTAFPSELPP TTTETFDYNF NMNVRTIERK NKCSAYGNAV
710 720 730 740 750
LTDSERENGF ADPNLKEENG SKKKLQSYMK EVKLEALIKA VLTAEPTLLH
760 770 780 790 800
PDQRINMDKI TEGDEFYHKL EANRFAKSMG YKQDFTMGSI GPDETPNGSY
810 820 830 840 850
QLSSIKSIRD VLLKDSKSSV DYELNKFIVV PGKMTHTIKG TKKSDDGDSK
860 870 880 890 900
TDGSGDMEDD FTSLAKMTNR KRKAGGKDGP SKKKKKDGAD KSLEKLARAM
910 920 930 940 950
LLDLLEISIP NSDASLSLEE QNQEIRKFWR EKQIHPDYIF LFPNAEEKRK
960 970 980 990 1000
LTPETTKQLC QKFMKVVGIC RDMIRPEPTS SENIRLKLVT TYMAGVRDYI
1010 1020 1030 1040 1050
KRLAEFLAKK LNYSSVEEMR GYAMSSIRMK NESVKKTQSS WMDPQSTSDP
1060 1070 1080 1090 1100
VQKMMERKIT SAYATHRIES ANTKVLPYTD SKLIPVCSEI PIPARMILCS
1110 1120 1130 1140 1150
VGETESDGCK RLGYNIEGYK RNEKDIKMAG EKQQPHSYLT PLEMKIKMDT
1160 1170 1180 1190 1200
FQKEAENIEK EKYVDGNKPE TAAREEIFKQ VREKEINCGV YIPWEIMAKD
1210 1220 1230 1240 1250
LCENAGYKDS DVLDPAVLAH ILKRADVKFE KLGNGGFASA LNCKTIAKLL
1260 1270 1280 1290 1300
AGYLDTMEDV NVTRPSLITN IFSDMDTICS MVNKIGMNMK SFFGSYDYAT
1310 1320 1330 1340 1350
FDMATFNLKD TLLKMISQEP ELGSVLHLLI TMATIYGVNT STNGKLFYKS
1360 1370 1380 1390 1400
YERDSQAAVV GIGGILNIFL GMDACKSSNA AREIKQAQRK INPMITTHMD
1410 1420 1430 1440 1450
YNMKRGGGID RWSTLDTAKC QGMSRYLGCY SFSTYPGQQG SNDIYTKLKL
1460 1470 1480 1490 1500
SGGFFYNSIP AHICAQSKSH NTNKVTMCLK NSGVLYSSFK RGGRNVDIAE
1510 1520 1530 1540 1550
LLNRGDLDDI NNTILSTNGL AQKIAAYFLS SIGIEPKTNG FPDMGNMSKS
1560 1570 1580 1590 1600
MFVRKIVKIH FSEFAEEDGE IMVERKVLKH ILGFVYPDDS VVEKPDMFMV
1610 1620 1630
YDPSAMDVDE DEDEDMDDES DDESDGEEMS GE
Length:1,632
Mass (Da):184,431
Last modified:July 5, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6D41924AD7A74862
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY509253 Genomic DNA Translation: AAS00914.1

NCBI Reference Sequences

More...
RefSeqi
YP_024567.1, NC_005881.2

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
2948158

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
vg:2948158

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY509253 Genomic DNA Translation: AAS00914.1
RefSeqiYP_024567.1, NC_005881.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Proteomic databases

PRIDEiQ6R7K1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi2948158
KEGGivg:2948158

Family and domain databases

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiY022_OSHVF
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6R7K1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: July 5, 2004
Last modified: May 10, 2017
This is version 35 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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