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Entry version 114 (02 Dec 2020)
Sequence version 1 (05 Jul 2004)
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Protein

60S ribosomal protein L19

Gene

Cnbd2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRibonucleoprotein, Ribosomal proteinARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
60S ribosomal protein L19ARBA annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Cnbd2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRattus norvegicus (Rat)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10116 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002494 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSRNOG00000019992, Expressed in testis and 20 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10116.ENSRNOP00000027086

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini102 – 204Cyclic nucleotide-bindingInterPro annotationAdd BLAST103

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni345 – 367DisorderedSequence analysisAdd BLAST23
Regioni1018 – 1042DisorderedSequence analysisAdd BLAST25

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi345 – 366PolyampholyteSequence analysisAdd BLAST22

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the eukaryotic ribosomal protein eL19 family.ARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1113, Eukaryota
KOG1696, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000003964

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_010930_0_0_1

Identification of Orthologs from Complete Genome Data

More...
OMAi
PMINTEY

TreeFam database of animal gene trees

More...
TreeFami
TF326269

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00038, CAP_ED, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.1650.10, 1 hit
2.60.120.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR035970, 60S_ribosomal_L19/L19e_sf
IPR043533, CNBD1/2
IPR038897, CNBD2
IPR018490, cNMP-bd-like
IPR018488, cNMP-bd_CS
IPR000595, cNMP-bd_dom
IPR000196, Ribosomal_L19/L19e
IPR015972, Ribosomal_L19/L19e_dom1
IPR014710, RmlC-like_jellyroll

The PANTHER Classification System

More...
PANTHERi
PTHR23011, PTHR23011, 1 hit
PTHR23011:SF35, PTHR23011:SF35, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00027, cNMP_binding, 1 hit
PF01280, Ribosomal_L19e, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00100, cNMP, 1 hit
SM01416, Ribosomal_L19e, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48140, SSF48140, 1 hit
SSF51206, SSF51206, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00888, CNMP_BINDING_1, 1 hit
PS50042, CNMP_BINDING_3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q6QI81-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLKGLYQLTV AIILMSRVCK MFRQGLRGFR EYQIIEPAQK KHPTFSFWDK
60 70 80 90 100
KKQGRISFDT QDFAAEEGHF PPRAISITQK KPSWRTDEEI QDLCNILQVL
110 120 130 140 150
DCYRNYTEYL QLLLAKVMRF ERFGRRRVIV KKGQRGNSFY FIYLGTVAVT
160 170 180 190 200
EDEDGSSAFL DPHPTLLHKG GFFGEMGLLS TAVRRATVVC MEETEFLVVD
210 220 230 240 250
REDFLANKLG DEVQKETQYR YDFFRKLDMF QSWSDEKLWQ LVALGRIEKF
260 270 280 290 300
PHGELVSKDI GNSAFITFIC KKSKLRHKNI AVYGHGVEWR GQGSTELCLT
310 320 330 340 350
PKPFWRTGTG IDPQVTKDIW CIFAKPMLVQ GALCYRSRQR TYATDKHVGK
360 370 380 390 400
PREASREAES HPVTDGLRDA KGNSAFSCIH QILVVWEGGL ARKEVTQLQK
410 420 430 440 450
QLTTAVSMFR PQMRLGSSVL HCGKKEVWLD PNETNGNAHA NSRQRVRKLT
460 470 480 490 500
KDGLIIWKPM TVHSGAHCQK STLALGKGRH MGIGKRKGTA NARMPEKGNC
510 520 530 540 550
EILRMVDLGT CRTYYRWVWQ QLELLDHKPL RVHNNEMSPK ERFKEFQIKS
560 570 580 590 600
YPLQDFTYLK LLRLQEAREQ PAMTFHRKIN KAENSLPKLL GPKVKSRYGH
610 620 630 640 650
SVKCSMVHTK YGELPKEAIV GVYMKVHLTE EGDVVASWGK GTNKNSPCTL
660 670 680 690 700
PRQYSDSGEL GESSAGKMLA TSLSTGNLSQ SPGEKAGVVV LSMQRWGNHQ
710 720 730 740 750
AFLPEIHRDP RSFILLSLGT ELIRVRKEKF YDLVDAETKA KIMKMDVDYP
760 770 780 790 800
SDEELCQSFL SENDWSIFRR DLLRLLVEPL KKKPFIPIQT KKKEIYNPKS
810 820 830 840 850
LLLDLCSLDK KVKVGGEPNG RWECMAIAMA TGDQTSELSL TVSSIKSHQQ
860 870 880 890 900
LICSAGGQAS ISAHPTIFSN DPADVHIKSP SPVSCDTGTC HSDDTLSQLF
910 920 930 940 950
RRQPCYELTE YTECVSLRQR FRLATGDCRV PASLGWKEDP RPNNRSFLSP
960 970 980 990 1000
LFGALSPSSS PIEASVHPVL SARSGSDPSL GWPSVLAQTR RLRPQKPRRA
1010 1020 1030 1040
SLGCQVVAIL PAMPCSPPPG DVLEGLAGAS PWPDLDSRGP VE
Length:1,042
Mass (Da):117,715
Last modified:July 5, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2BB365EDB2CAC62E
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AABR07054399 Genomic DNA No translation available.
AABR07054400 Genomic DNA No translation available.
AABR07054401 Genomic DNA No translation available.
AY539878 mRNA Translation: AAS66218.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSRNOT00000027086; ENSRNOP00000027086; ENSRNOG00000019992

UCSC genome browser

More...
UCSCi
RGD:1311678, rat

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07054399 Genomic DNA No translation available.
AABR07054400 Genomic DNA No translation available.
AABR07054401 Genomic DNA No translation available.
AY539878 mRNA Translation: AAS66218.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000027086

Genome annotation databases

EnsembliENSRNOT00000027086; ENSRNOP00000027086; ENSRNOG00000019992
UCSCiRGD:1311678, rat

Phylogenomic databases

eggNOGiKOG1113, Eukaryota
KOG1696, Eukaryota
GeneTreeiENSGT00390000003964
HOGENOMiCLU_010930_0_0_1
OMAiPMINTEY
TreeFamiTF326269

Gene expression databases

BgeeiENSRNOG00000019992, Expressed in testis and 20 other tissues

Family and domain databases

CDDicd00038, CAP_ED, 1 hit
Gene3Di1.10.1650.10, 1 hit
2.60.120.10, 1 hit
InterProiView protein in InterPro
IPR035970, 60S_ribosomal_L19/L19e_sf
IPR043533, CNBD1/2
IPR038897, CNBD2
IPR018490, cNMP-bd-like
IPR018488, cNMP-bd_CS
IPR000595, cNMP-bd_dom
IPR000196, Ribosomal_L19/L19e
IPR015972, Ribosomal_L19/L19e_dom1
IPR014710, RmlC-like_jellyroll
PANTHERiPTHR23011, PTHR23011, 1 hit
PTHR23011:SF35, PTHR23011:SF35, 1 hit
PfamiView protein in Pfam
PF00027, cNMP_binding, 1 hit
PF01280, Ribosomal_L19e, 1 hit
SMARTiView protein in SMART
SM00100, cNMP, 1 hit
SM01416, Ribosomal_L19e, 1 hit
SUPFAMiSSF48140, SSF48140, 1 hit
SSF51206, SSF51206, 1 hit
PROSITEiView protein in PROSITE
PS00888, CNMP_BINDING_1, 1 hit
PS50042, CNMP_BINDING_3, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ6QI81_RAT
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6QI81
Secondary accession number(s): F1LP09
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: December 2, 2020
This is version 114 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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