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Entry version 68 (07 Oct 2020)
Sequence version 1 (05 Jul 2004)
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Protein

Probable tape measure protein

Gene

D18-19

Organism
Escherichia phage T5 (Enterobacteria phage T5)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Fills the tail tube with its long coiled-coil domain and has pore-forming properties for host membrane penetration. Probable exolysin involved in host peptidoglycan digestion necessary for viral DNA entry into the host cell. Also functions as a tape measure protein that serves as a base for tail tube protein polymerization and acts as a template for tail length determination.2 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionAntimicrobial, Bacteriolytic enzyme, Viral long flexible tail ejection system
Biological processDegradation of host cell envelope components during virus entry, Degradation of host peptidoglycans during virus entry, Pore-mediated penetration of viral genome into host cell, Viral genome ejection through host cell envelope, Viral penetration into host cytoplasm, Viral release from host cell, Viral tail assembly, Virus entry into host cell

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Probable tape measure protein1 Publication
Alternative name(s):
Tail protein pb21 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:D18-19Imported
ORF Names:T5.140Imported, T5p136Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia phage T5 (Enterobacteria phage T5)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10726 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiVirusesDuplodnaviriaHeunggongviraeUroviricotaCaudoviricetesCaudoviralesDemerecviridaeMarkadamsvirinaeTequintavirus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section only exists in viral entries and indicates the host(s) either as a specific organism or taxonomic group of organisms that are susceptible to be infected by a virus.<p><a href='/help/virus_host' target='_top'>More...</a></p>Virus hostiEscherichia coli [TaxID: 562]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002141 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome
  • UP000002107 Componenti: Genome
  • UP000002503 Componenti: Genome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Virion

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004329751 – 1148Probable tape measure proteinAdd BLAST1148
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes a propeptide, which is a part of a protein that is cleaved during maturation or activation. Once cleaved, a propeptide generally has no independent biological function.<p><a href='/help/propep' target='_top'>More...</a></p>PropeptideiPRO_00004355471149 – 12191 PublicationAdd BLAST71

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections ('Function', 'PTM / Processing', 'Pathology and Biotech') according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei?1148 – ?1149Cleavage; by the prohead protease1 Publication2

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
Q6QGE7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Keywords - Developmental stagei

Late protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q6QGE7

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili441 – 519Sequence analysisAdd BLAST79
Coiled coili838 – 941Sequence analysisAdd BLAST104
Coiled coili1003 – 1032Sequence analysisAdd BLAST30

Keywords - Domaini

Coiled coil

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q6QGE7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTDKLIRELL IDVKQKGATR TAKSIENVSD ALENAAAASE LTNEQLGKMP
60 70 80 90 100
RTLYSIERAA DRAAKSLTKM QASRGMAGIT KSIDGIGDKL DYLAIQLIEV
110 120 130 140 150
TDKLEIGFDG VSRSVKAMGN DVAAATEKVQ DRLYDTNRAL GGTSKGFNDT
160 170 180 190 200
AGAAGRASRA LGNTSGSARG ATRDFAAMAK IGGRLPIMYA ALASNVFVLQ
210 220 230 240 250
TAFESLKVGD QLNRLEQFGT IVGTMTGTPV QTLALSLQNA TNGAISFEEA
260 270 280 290 300
MRQASSASAY GFDSEQLEQF GLVARRAAAV LGVDMTDALN RVIKGVSKQE
310 320 330 340 350
IELLDELGVT IRLNDAYENY VKQLNATSTG IKYTVDSLTT YQKQQAYANE
360 370 380 390 400
VIAESTRRFG YLDDALKATS WEQFAANANS ALRSLQQSAA TYLNPVMDTL
410 420 430 440 450
NTFLYQTKSS QMRVSAMARS ASAKTTPAEN VTALIENAVG AREDLDTYLK
460 470 480 490 500
ESEERVKKAQ ELKQQLDDLK AKQAATAPIA NALTAGGIGG DESNKLVVQL
510 520 530 540 550
TNELARQNKE IEERTKTEKV LRQAVQDTGE ALLRNGKLAE QLGAKMKYAD
560 570 580 590 600
TAVPGDKGVF EVDPNNLKAV SEIQKNFDFL KKSSSDTANN IRMAASSITN
610 620 630 640 650
AKKASSDLNS VVKAVEDTSK VTGQSADTLV KNLNLGFSSL DQMKAAQKGL
660 670 680 690 700
SEYVTAMDKS EQNALEVAKR KDEVYNQTKD KAKAEAAARE VLLRQQQEQL
710 720 730 740 750
TAAKALLAIN PNDPEALKQV AKIETEILNT KAQGFENAKK TKDYTDKILG
760 770 780 790 800
VDREIALLND RTMTSTQYRL AQLRLELQLE QEKTELYSKQ ADGQAKVEQS
810 820 830 840 850
RRAQAQISRE IWEAEKQGTA SHVSALMDAL EVSQTQRNVT GQSQILTERL
860 870 880 890 900
SILQQQLELS KGNTEEELKY RNEIYKTSAA LEQLKKQRES QMQQQVGSSV
910 920 930 940 950
GATYTPTTGL IGEDKDFADM QNRMASYDQA ISKLSELNSE ATAVAQSMGN
960 970 980 990 1000
LTNAMIQFSQ GSLDTTSMIA SGMQTVASMI QYSTSQQVSA IDQAIAAEQK
1010 1020 1030 1040 1050
RDGKSEASKA KLKKLEAEKL KIQQDAAKKQ IIIQTAVAVM QAATAVPYPF
1060 1070 1080 1090 1100
SIPLMVAAGL AGALALAQAS SASGMSSIAD SGADTTQYLT LGERQKNVDV
1110 1120 1130 1140 1150
SMQASSGELS YLRGDKGIGN ANSFVPRAEG GMMYPGVSYQ MGEHGTEVVT
1160 1170 1180 1190 1200
PMVPMKATPN DQLSDGSKTT SGRPIILNIS TMDAASFRDF ASNNSTAFRD
1210
AVELALNENG TTLKSLGNS
Length:1,219
Mass (Da):131,496
Last modified:July 5, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4A47C5F3DB7464D9
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY543070 Genomic DNA Translation: AAQ92756.2
AY692264 Genomic DNA Translation: AAU05275.1
AY587007 Genomic DNA Translation: AAX12066.1

NCBI Reference Sequences

More...
RefSeqi
YP_006968.1, NC_005859.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
2777629

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
vg:2777629

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY543070 Genomic DNA Translation: AAQ92756.2
AY692264 Genomic DNA Translation: AAU05275.1
AY587007 Genomic DNA Translation: AAX12066.1
RefSeqiYP_006968.1, NC_005859.1

3D structure databases

SMRiQ6QGE7
ModBaseiSearch...

Proteomic databases

PRIDEiQ6QGE7

Genome annotation databases

GeneIDi2777629
KEGGivg:2777629

Family and domain databases

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTMP_BPT5
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6QGE7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 29, 2015
Last sequence update: July 5, 2004
Last modified: October 7, 2020
This is version 68 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome
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