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UniProtKB - Q6QGE7 (TMP_BPT5)

Entry version 69 (25 May 2022)
Sequence version 1 (05 Jul 2004)
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Protein

Tape measure protein pb2

Gene

D18-19

Organism
Escherichia phage T5 (Enterobacteria phage T5)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Fills the tail tube with its long coiled-coil domain and has pore-forming properties for host membrane penetration. Probable exolysin involved in host peptidoglycan digestion necessary for viral DNA entry into the host cell. Also functions as a tape measure protein that serves as a base for tail tube protein polymerization and acts as a template for tail length determination.

2 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionAntimicrobial, Bacteriolytic enzyme, Viral long flexible tail ejection system
Biological processDegradation of host cell envelope components during virus entry, Degradation of host peptidoglycans during virus entry, Pore-mediated penetration of viral genome into host cell, Viral genome ejection through host cell envelope, Viral penetration into host cytoplasm, Viral release from host cell, Viral tail assembly, Virus entry into host cell

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Tape measure protein pb21 Publication
Short name:
TMP-pb2Curated
Alternative name(s):
Pore-forming protein pb2Curated
Tail protein pb21 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:D18-19
ORF Names:T5.140, T5p136Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia phage T5 (Enterobacteria phage T5)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri2695836 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiViruses › Duplodnaviria › Heunggongvirae › Uroviricota › Caudoviricetes › Caudovirales › Demerecviridae › Markadamsvirinae › Tequintavirus ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section only exists in viral entries and indicates the host(s) either as a specific organism or taxonomic group of organisms that are susceptible to be infected by a virus.<p><a href='/help/virus_host' target='_top'>More...</a></p>Virus hostiEscherichia coli [TaxID: 562]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002141 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome
  • UP000002503 Componenti: Genome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Virion

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004329751 – 1148Tape measure protein pb2Add BLAST1148
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes a propeptide, which is a part of a protein that is cleaved during maturation or activation. Once cleaved, a propeptide generally has no independent biological function.<p><a href='/help/propep' target='_top'>More...</a></p>PropeptideiPRO_00004355471149 – 12191 PublicationAdd BLAST71

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections ('Function', 'PTM / Processing', 'Pathology and Biotech') according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei?1127 – ?1128Cleavage; by the prohead protease1 Publication2

Proteomic databases

PRoteomics IDEntifications database

More...PRIDEi		Q6QGE7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Keywords - Developmental stagei

Late protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q6QGE7

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili441 – 519Sequence analysisAdd BLAST79
Coiled coili838 – 941Sequence analysisAdd BLAST104
Coiled coili1003 – 1032Sequence analysisAdd BLAST30

Keywords - Domaini

Coiled coil

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q6QGE7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTDKLIRELL IDVKQKGATR TAKSIENVSD ALENAAAASE LTNEQLGKMP 
        60         70         80         90        100
RTLYSIERAA DRAAKSLTKM QASRGMAGIT KSIDGIGDKL DYLAIQLIEV 
       110        120        130        140        150
TDKLEIGFDG VSRSVKAMGN DVAAATEKVQ DRLYDTNRAL GGTSKGFNDT 
       160        170        180        190        200
AGAAGRASRA LGNTSGSARG ATRDFAAMAK IGGRLPIMYA ALASNVFVLQ 
       210        220        230        240        250
TAFESLKVGD QLNRLEQFGT IVGTMTGTPV QTLALSLQNA TNGAISFEEA 
       260        270        280        290        300
MRQASSASAY GFDSEQLEQF GLVARRAAAV LGVDMTDALN RVIKGVSKQE 
       310        320        330        340        350
IELLDELGVT IRLNDAYENY VKQLNATSTG IKYTVDSLTT YQKQQAYANE 
       360        370        380        390        400
VIAESTRRFG YLDDALKATS WEQFAANANS ALRSLQQSAA TYLNPVMDTL 
       410        420        430        440        450
NTFLYQTKSS QMRVSAMARS ASAKTTPAEN VTALIENAVG AREDLDTYLK 
       460        470        480        490        500
ESEERVKKAQ ELKQQLDDLK AKQAATAPIA NALTAGGIGG DESNKLVVQL 
       510        520        530        540        550
TNELARQNKE IEERTKTEKV LRQAVQDTGE ALLRNGKLAE QLGAKMKYAD 
       560        570        580        590        600
TAVPGDKGVF EVDPNNLKAV SEIQKNFDFL KKSSSDTANN IRMAASSITN 
       610        620        630        640        650
AKKASSDLNS VVKAVEDTSK VTGQSADTLV KNLNLGFSSL DQMKAAQKGL 
       660        670        680        690        700
SEYVTAMDKS EQNALEVAKR KDEVYNQTKD KAKAEAAARE VLLRQQQEQL 
       710        720        730        740        750
TAAKALLAIN PNDPEALKQV AKIETEILNT KAQGFENAKK TKDYTDKILG 
       760        770        780        790        800
VDREIALLND RTMTSTQYRL AQLRLELQLE QEKTELYSKQ ADGQAKVEQS 
       810        820        830        840        850
RRAQAQISRE IWEAEKQGTA SHVSALMDAL EVSQTQRNVT GQSQILTERL 
       860        870        880        890        900
SILQQQLELS KGNTEEELKY RNEIYKTSAA LEQLKKQRES QMQQQVGSSV 
       910        920        930        940        950
GATYTPTTGL IGEDKDFADM QNRMASYDQA ISKLSELNSE ATAVAQSMGN 
       960        970        980        990       1000
LTNAMIQFSQ GSLDTTSMIA SGMQTVASMI QYSTSQQVSA IDQAIAAEQK 
      1010       1020       1030       1040       1050
RDGKSEASKA KLKKLEAEKL KIQQDAAKKQ IIIQTAVAVM QAATAVPYPF 
      1060       1070       1080       1090       1100
SIPLMVAAGL AGALALAQAS SASGMSSIAD SGADTTQYLT LGERQKNVDV 
      1110       1120       1130       1140       1150
SMQASSGELS YLRGDKGIGN ANSFVPRAEG GMMYPGVSYQ MGEHGTEVVT 
      1160       1170       1180       1190       1200
PMVPMKATPN DQLSDGSKTT SGRPIILNIS TMDAASFRDF ASNNSTAFRD 
      1210 
AVELALNENG TTLKSLGNS
Length:1,219
Mass (Da):131,496
Last modified:July 5, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4A47C5F3DB7464D9
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AY692264 Genomic DNA Translation: AAU05275.1
AY587007 Genomic DNA Translation: AAX12066.1

NCBI Reference Sequences

More...RefSeqi		YP_006968.1, NC_005859.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...GeneIDi		2777629

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		vg:2777629

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY692264 Genomic DNA Translation: AAU05275.1
AY587007 Genomic DNA Translation: AAX12066.1
RefSeqiYP_006968.1, NC_005859.1

3D structure databases

SMRiQ6QGE7
ModBaseiSearch...

Proteomic databases

PRIDEiQ6QGE7

Genome annotation databases

GeneIDi2777629
KEGGivg:2777629

Family and domain databases

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTMP_BPT5
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6QGE7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 29, 2015
Last sequence update: July 5, 2004
Last modified: May 25, 2022
This is version 69 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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