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Entry version 109 (02 Jun 2021)
Sequence version 2 (16 Aug 2004)
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Protein

40S ribosomal protein S28

Gene

RPS28

Organism
Sus scrofa (Pig)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-SSC-156827, L13a-mediated translational silencing of Ceruloplasmin expression
R-SSC-1799339, SRP-dependent cotranslational protein targeting to membrane
R-SSC-72649, Translation initiation complex formation
R-SSC-72689, Formation of a pool of free 40S subunits
R-SSC-72702, Ribosomal scanning and start codon recognition
R-SSC-72706, GTP hydrolysis and joining of the 60S ribosomal subunit
R-SSC-975956, Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-SSC-975957, Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
40S ribosomal protein S28
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RPS28
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSus scrofa (Pig)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9823 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaArtiodactylaSuinaSuidaeSus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000314985 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2
  • UP000008227 Componenti: Chromosome 2

Organism-specific databases

Vertebrate Gene Nomenclature Database

More...
VGNCi
VGNC:100854, RPS28

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm, Endoplasmic reticulum

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001368241 – 6940S ribosomal protein S28Add BLAST69

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1N-acetylmethionineBy similarity1
Modified residuei41PhosphoserineBy similarity1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q6QAT1

PeptideAtlas

More...
PeptideAtlasi
Q6QAT1

PRoteomics IDEntifications database

More...
PRIDEi
Q6QAT1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSSSCG00000013597, Expressed in uterus and 48 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q6QAT1, SS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the 40S small ribosomal subunit.

1 Publication

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9823.ENSSSCP00000014450

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q6QAT1

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3502, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00910000144227

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_178987_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q6QAT1

Identification of Orthologs from Complete Genome Data

More...
OMAi
MHGEASQ

Database of Orthologous Groups

More...
OrthoDBi
1578965at2759

TreeFam database of animal gene trees

More...
TreeFami
TF300136

Family and domain databases

Conserved Domains Database

More...
CDDi
cd04457, S1_S28E, 1 hit

HAMAP database of protein families

More...
HAMAPi
MF_00292, Ribosomal_S28e, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR012340, NA-bd_OB-fold
IPR000289, Ribosomal_S28e
IPR028626, Ribosomal_S28e_CS

The PANTHER Classification System

More...
PANTHERi
PTHR10769, PTHR10769, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01200, Ribosomal_S28e, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50249, SSF50249, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00961, RIBOSOMAL_S28E, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q6QAT1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDTSRVQPIK LARVTKVLGR TGSQGQCTQV RVEFMDDTSR SIIRNVKGPV
60
REGDVLTLLE SEREARRLR
Length:69
Mass (Da):7,841
Last modified:August 16, 2004 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i49902FE9376EB74F
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAS55896 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY550038 mRNA Translation: AAS55896.1 Different initiation.

NCBI Reference Sequences

More...
RefSeqi
NP_001001587.1, NM_001001587.1
XP_013842818.1, XM_013987364.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSSSCT00000014851; ENSSSCP00000014450; ENSSSCG00000013597
ENSSSCT00015102681; ENSSSCP00015042678; ENSSSCG00015076105
ENSSSCT00025023327; ENSSSCP00025009750; ENSSSCG00025017262
ENSSSCT00030024856; ENSSSCP00030011102; ENSSSCG00030018006
ENSSSCT00035098887; ENSSSCP00035041815; ENSSSCG00035073015
ENSSSCT00040003494; ENSSSCP00040001065; ENSSSCG00040002825
ENSSSCT00045052072; ENSSSCP00045036239; ENSSSCG00045030525
ENSSSCT00055013312; ENSSSCP00055010465; ENSSSCG00055006878
ENSSSCT00060030186; ENSSSCP00060012962; ENSSSCG00060022239
ENSSSCT00065054864; ENSSSCP00065023839; ENSSSCG00065040129
ENSSSCT00070050597; ENSSSCP00070042768; ENSSSCG00070025313

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
414420

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ssc:414420

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY550038 mRNA Translation: AAS55896.1 Different initiation.
RefSeqiNP_001001587.1, NM_001001587.1
XP_013842818.1, XM_013987364.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3J7Pelectron microscopy3.50Sc1-69[»]
3J7Relectron microscopy3.90Sc1-69[»]
SMRiQ6QAT1
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000014450

Proteomic databases

PaxDbiQ6QAT1
PeptideAtlasiQ6QAT1
PRIDEiQ6QAT1

Genome annotation databases

EnsembliENSSSCT00000014851; ENSSSCP00000014450; ENSSSCG00000013597
ENSSSCT00015102681; ENSSSCP00015042678; ENSSSCG00015076105
ENSSSCT00025023327; ENSSSCP00025009750; ENSSSCG00025017262
ENSSSCT00030024856; ENSSSCP00030011102; ENSSSCG00030018006
ENSSSCT00035098887; ENSSSCP00035041815; ENSSSCG00035073015
ENSSSCT00040003494; ENSSSCP00040001065; ENSSSCG00040002825
ENSSSCT00045052072; ENSSSCP00045036239; ENSSSCG00045030525
ENSSSCT00055013312; ENSSSCP00055010465; ENSSSCG00055006878
ENSSSCT00060030186; ENSSSCP00060012962; ENSSSCG00060022239
ENSSSCT00065054864; ENSSSCP00065023839; ENSSSCG00065040129
ENSSSCT00070050597; ENSSSCP00070042768; ENSSSCG00070025313
GeneIDi414420
KEGGissc:414420

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
6234
VGNCiVGNC:100854, RPS28

Phylogenomic databases

eggNOGiKOG3502, Eukaryota
GeneTreeiENSGT00910000144227
HOGENOMiCLU_178987_1_0_1
InParanoidiQ6QAT1
OMAiMHGEASQ
OrthoDBi1578965at2759
TreeFamiTF300136

Enzyme and pathway databases

ReactomeiR-SSC-156827, L13a-mediated translational silencing of Ceruloplasmin expression
R-SSC-1799339, SRP-dependent cotranslational protein targeting to membrane
R-SSC-72649, Translation initiation complex formation
R-SSC-72689, Formation of a pool of free 40S subunits
R-SSC-72702, Ribosomal scanning and start codon recognition
R-SSC-72706, GTP hydrolysis and joining of the 60S ribosomal subunit
R-SSC-975956, Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-SSC-975957, Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Gene expression databases

BgeeiENSSSCG00000013597, Expressed in uterus and 48 other tissues
GenevisibleiQ6QAT1, SS

Family and domain databases

CDDicd04457, S1_S28E, 1 hit
HAMAPiMF_00292, Ribosomal_S28e, 1 hit
InterProiView protein in InterPro
IPR012340, NA-bd_OB-fold
IPR000289, Ribosomal_S28e
IPR028626, Ribosomal_S28e_CS
PANTHERiPTHR10769, PTHR10769, 1 hit
PfamiView protein in Pfam
PF01200, Ribosomal_S28e, 1 hit
SUPFAMiSSF50249, SSF50249, 1 hit
PROSITEiView protein in PROSITE
PS00961, RIBOSOMAL_S28E, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRS28_PIG
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6QAT1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 16, 2004
Last sequence update: August 16, 2004
Last modified: June 2, 2021
This is version 109 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families
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