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Entry version 135 (17 Jun 2020)
Sequence version 1 (05 Jul 2004)
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Protein

Zinc transporter 9

Gene

SLC30A9

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Acts as a zinc transporter involved in intracellular zinc homeostasis (PubMed:28334855). Functions as a secondary coactivator for nuclear receptors by cooperating with p160 coactivators subtypes. Plays a role in transcriptional activation of Wnt-responsive genes (By similarity).By similarity1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processIon transport, Transcription, Transcription regulation, Transport, Zinc transport
LigandZinc

Enzyme and pathway databases

SIGNOR Signaling Network Open Resource

More...
SIGNORi
Q6PML9

Protein family/group databases

Transport Classification Database

More...
TCDBi
2.A.4.6.1 the cation diffusion facilitator (cdf) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc transporter 9
Short name:
ZnT-9
Alternative name(s):
Human embryonic lung protein1 Publication
Short name:
HuEL1 Publication
Solute carrier family 30 member 9
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SLC30A9
Synonyms:C4orf1, HUEL
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000014824.13

Human Gene Nomenclature Database

More...
HGNCi
HGNC:1329 SLC30A9

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
604604 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q6PML9

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei239 – 259HelicalSequence analysisAdd BLAST21
Transmembranei314 – 334HelicalSequence analysisAdd BLAST21
Transmembranei342 – 362HelicalSequence analysisAdd BLAST21
Transmembranei392 – 412HelicalSequence analysisAdd BLAST21
Transmembranei424 – 444HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Cytoplasm, Cytoplasmic vesicle, Endoplasmic reticulum, Membrane, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section provides information on the disease(s) associated with genetic variations in a given protein. The information is extracted from the scientific literature and diseases that are also described in the <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=omim">OMIM</a> database are represented with a <a href="http://www.uniprot.org/diseases">controlled vocabulary</a> in the following way:<p><a href='/help/involvement_in_disease' target='_top'>More...</a></p>Involvement in diseasei

Birk-Landau-Perez syndrome (BILAPES)1 Publication
The disease is caused by mutations affecting the gene represented in this entry.
Disease descriptionAn autosomal recessive syndrome characterized by early-childhood onset of different combinations of intellectual disability, muscle weakness, camptocormia, oculomotor apraxia, and nephropathy.
Related information in OMIM
Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_079365350Missing in BILAPES; no effect on Wnt-signaling; no change in cytoplasmic vesicle subcellular location; decrease in cytosolic free zinc levels. 1 Publication1

Keywords - Diseasei

Disease mutation

Organism-specific databases

DisGeNET

More...
DisGeNETi
10463

MalaCards human disease database

More...
MalaCardsi
SLC30A9
MIMi617595 phenotype

Open Targets

More...
OpenTargetsi
ENSG00000014824

Orphanet; a database dedicated to information on rare diseases and orphan drugs

More...
Orphaneti
505242 Psychomotor regression-oculomotor apraxia-movement disorder-nephropathy syndrome

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA25909

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q6PML9 Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
SLC30A9

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74722746

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002958051 – 568Zinc transporter 9Add BLAST568

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q6PML9

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q6PML9

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q6PML9

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q6PML9

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q6PML9

PeptideAtlas

More...
PeptideAtlasi
Q6PML9

PRoteomics IDEntifications database

More...
PRIDEi
Q6PML9

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
67254

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q6PML9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q6PML9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Ubiquitously expressed in fetal and adult tissues and cancer cell lines.2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000014824 Expressed in forebrain and 238 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q6PML9 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q6PML9 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000014824 Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with GRIP1, ESR1 and AR.

By similarity

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
115726, 22 interactors

Protein interaction database and analysis system

More...
IntActi
Q6PML9, 14 interactors

Molecular INTeraction database

More...
MINTi
Q6PML9

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000264451

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q6PML9 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1568
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q6PML9

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
Q6PML9

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi462 – 466LXXLL motif5

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2802 Eukaryota
COG0053 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000008346

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_021126_3_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q6PML9

KEGG Orthology (KO)

More...
KOi
K14696

Identification of Orthologs from Complete Genome Data

More...
OMAi
MVAGACM

Database of Orthologous Groups

More...
OrthoDBi
667718at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q6PML9

TreeFam database of animal gene trees

More...
TreeFami
TF314526

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.1510.10, 1 hit
3.90.530.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002524 Cation_efflux
IPR027469 Cation_efflux_TMD_sf
IPR009061 DNA-bd_dom_put_sf
IPR040177 SLC30A9
IPR037129 XPA_sf

The PANTHER Classification System

More...
PANTHERi
PTHR13414 PTHR13414, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01545 Cation_efflux, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF161111 SSF161111, 1 hit
SSF46955 SSF46955, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01297 CDF, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q6PML9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLPGLAAAAA HRCSWSSLCR LRLRCRAAAC NPSDRQEWQN LVTFGSFSNM
60 70 80 90 100
VPCSHPYIGT LSQVKLYSTN VQKEGQGSQT LRVEKVPSFE TAEGIGTELK
110 120 130 140 150
APLKQEPLQV RVKAVLKKRE YGSKYTQNNF ITGVRAINEF CLKSSDLEQL
160 170 180 190 200
RKIRRRSPHE DTESFTVYLR SDVEAKSLEV WGSPEALARE KKLRKEAEIE
210 220 230 240 250
YRERLFRNQK ILREYRDFLG NTKPRSRTAS VFFKGPGKVV MVAICINGLN
260 270 280 290 300
CFFKFLAWIY TGSASMFSEA IHSLSDTCNQ GLLALGISKS VQTPDPSHPY
310 320 330 340 350
GFSNMRYISS LISGVGIFMM GAGLSWYHGV MGLLHPQPIE SLLWAYCILA
360 370 380 390 400
GSLVSEGATL LVAVNELRRN ARAKGMSFYK YVMESRDPST NVILLEDTAA
410 420 430 440 450
VLGVIIAATC MGLTSITGNP LYDSLGSLGV GTLLGMVSAF LIYTNTEALL
460 470 480 490 500
GRSIQPEQVQ RLTELLENDP SVRAIHDVKA TDLGLGKVRF KAEVDFDGRV
510 520 530 540 550
VTRSYLEKQD FDQMLQEIQE VKTPEELETF MLKHGENIID TLGAEVDRLE
560
KELKKRNPEV RHVDLEIL
Length:568
Mass (Da):63,515
Last modified:July 5, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iCA59839CA983FDC2
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D6R9M6D6R9M6_HUMAN
Zinc transporter 9
SLC30A9
119Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAP83846 differs from that shown. Unlikely isoform. Aberrant splice sites.Curated
The sequence AAY40966 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti141C → Y in AAP83846 (Ref. 3) Curated1
Sequence conflicti356E → V in AAP83846 (Ref. 3) Curated1
Sequence conflicti401V → A in AAH22981 (PubMed:15489334).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_05200350M → V3 PublicationsCorresponds to variant dbSNP:rs1047626Ensembl.1
Natural variantiVAR_05200497T → A3 PublicationsCorresponds to variant dbSNP:rs2581423Ensembl.1
Natural variantiVAR_079365350Missing in BILAPES; no effect on Wnt-signaling; no change in cytoplasmic vesicle subcellular location; decrease in cytosolic free zinc levels. 1 Publication1
Natural variantiVAR_052005353L → S. Corresponds to variant dbSNP:rs1801962Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF006621 mRNA Translation: AAB87763.2
AY319413 mRNA Translation: AAP83846.1 Sequence problems.
AY594282 mRNA Translation: AAT02479.1
AC113151 Genomic DNA Translation: AAY40966.1 Sequence problems.
BC007732 mRNA Translation: AAH07732.1
BC016949 mRNA Translation: AAH16949.1
BC022981 mRNA Translation: AAH22981.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS3465.1

NCBI Reference Sequences

More...
RefSeqi
NP_006336.3, NM_006345.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000264451; ENSP00000264451; ENSG00000014824

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
10463

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:10463

UCSC genome browser

More...
UCSCi
uc003gwl.4 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF006621 mRNA Translation: AAB87763.2
AY319413 mRNA Translation: AAP83846.1 Sequence problems.
AY594282 mRNA Translation: AAT02479.1
AC113151 Genomic DNA Translation: AAY40966.1 Sequence problems.
BC007732 mRNA Translation: AAH07732.1
BC016949 mRNA Translation: AAH16949.1
BC022981 mRNA Translation: AAH22981.1
CCDSiCCDS3465.1
RefSeqiNP_006336.3, NM_006345.3

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2ENKNMR-A124-217[»]
SMRiQ6PML9
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi115726, 22 interactors
IntActiQ6PML9, 14 interactors
MINTiQ6PML9
STRINGi9606.ENSP00000264451

Protein family/group databases

TCDBi2.A.4.6.1 the cation diffusion facilitator (cdf) family

PTM databases

iPTMnetiQ6PML9
PhosphoSitePlusiQ6PML9

Polymorphism and mutation databases

BioMutaiSLC30A9
DMDMi74722746

Proteomic databases

EPDiQ6PML9
jPOSTiQ6PML9
MassIVEiQ6PML9
MaxQBiQ6PML9
PaxDbiQ6PML9
PeptideAtlasiQ6PML9
PRIDEiQ6PML9
ProteomicsDBi67254

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
1339 147 antibodies

Genome annotation databases

EnsembliENST00000264451; ENSP00000264451; ENSG00000014824
GeneIDi10463
KEGGihsa:10463
UCSCiuc003gwl.4 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
10463
DisGeNETi10463
EuPathDBiHostDB:ENSG00000014824.13

GeneCards: human genes, protein and diseases

More...
GeneCardsi
SLC30A9
HGNCiHGNC:1329 SLC30A9
HPAiENSG00000014824 Low tissue specificity
MalaCardsiSLC30A9
MIMi604604 gene
617595 phenotype
neXtProtiNX_Q6PML9
OpenTargetsiENSG00000014824
Orphaneti505242 Psychomotor regression-oculomotor apraxia-movement disorder-nephropathy syndrome
PharmGKBiPA25909

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG2802 Eukaryota
COG0053 LUCA
GeneTreeiENSGT00390000008346
HOGENOMiCLU_021126_3_0_1
InParanoidiQ6PML9
KOiK14696
OMAiMVAGACM
OrthoDBi667718at2759
PhylomeDBiQ6PML9
TreeFamiTF314526

Enzyme and pathway databases

SIGNORiQ6PML9

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
10463 77 hits in 792 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
SLC30A9 human
EvolutionaryTraceiQ6PML9

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
10463
PharosiQ6PML9 Tbio

Protein Ontology

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PROi
PR:Q6PML9
RNActiQ6PML9 protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000014824 Expressed in forebrain and 238 other tissues
ExpressionAtlasiQ6PML9 baseline and differential
GenevisibleiQ6PML9 HS

Family and domain databases

Gene3Di1.20.1510.10, 1 hit
3.90.530.10, 1 hit
InterProiView protein in InterPro
IPR002524 Cation_efflux
IPR027469 Cation_efflux_TMD_sf
IPR009061 DNA-bd_dom_put_sf
IPR040177 SLC30A9
IPR037129 XPA_sf
PANTHERiPTHR13414 PTHR13414, 1 hit
PfamiView protein in Pfam
PF01545 Cation_efflux, 1 hit
SUPFAMiSSF161111 SSF161111, 1 hit
SSF46955 SSF46955, 1 hit
TIGRFAMsiTIGR01297 CDF, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZNT9_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6PML9
Secondary accession number(s): Q4W5B6
, Q7Z5I7, Q8TBB2, Q9Y6R2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 24, 2007
Last sequence update: July 5, 2004
Last modified: June 17, 2020
This is version 135 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  6. Human chromosome 4
    Human chromosome 4: entries, gene names and cross-references to MIM
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