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Entry version 116 (11 Dec 2019)
Sequence version 1 (05 Jul 2004)
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Protein

DALR anticodon-binding domain-containing protein 3

Gene

Dalrd3

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
DALR anticodon-binding domain-containing protein 3
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Dalrd3
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 9

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1915039 Dalrd3

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003158491 – 538DALR anticodon-binding domain-containing protein 3Add BLAST538

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q6PJN8

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q6PJN8

PeptideAtlas

More...
PeptideAtlasi
Q6PJN8

PRoteomics IDEntifications database

More...
PRIDEi
Q6PJN8

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q6PJN8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q6PJN8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000019039 Expressed in 286 organ(s), highest expression level in cerebellum

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q6PJN8 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q6PJN8 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000019183

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q6PJN8 protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1195 Eukaryota
COG0018 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000014621

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000043068

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q6PJN8

Identification of Orthologs from Complete Genome Data

More...
OMAi
RDPHMLT

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q6PJN8

TreeFam database of animal gene trees

More...
TreeFami
TF325601

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR008909 DALR_anticod-bd
IPR037380 DALRD3
IPR009080 tRNAsynth_Ia_anticodon-bd

The PANTHER Classification System

More...
PANTHERi
PTHR16043 PTHR16043, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05746 DALR_1, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00836 DALR_1, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47323 SSF47323, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q6PJN8-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MATGRLGVGE TLEALNAAVG PGSPVWFKET HARHLRVRDF LAPRSALQAR
60 70 80 90 100
FRDGQVPECV FRAVSCLQGP GVAPVLRCAP TPAGLSLQLQ RPAVFEHVLG
110 120 130 140 150
ALASYATPAK PASPGPRVVL HCPALRCNSG TLRLSQLRAV LVADHLVRVL
160 170 180 190 200
RAHGVRVCSV PPVRDPHMST FLQKLRVEWP TASKSTSTET LRTCVLANLN
210 220 230 240 250
GSKEATLPPG VLGRLCLKEL VEQRGTAGYD PSIDHCLVTE DVLSVLSELQ
260 270 280 290 300
EAVRHWPEGG HPGPAGRPDA GVDDCVVIHV VSCEEAFQQQ KLDLLWQKLD
310 320 330 340 350
DRAPHKQKHL VCGPVKMAGV PGTQLTAPQY YRLRHAQVCE ASALKHGGDL
360 370 380 390 400
AQDPAWTETF DILSVATIKF EMLSTAPQSQ LLLAHSTIST KGTKSGTFVM
410 420 430 440 450
YNCARLATLF EGYKHGTEQG LYPTFPLVSS LDFSLLHDEG EWLLLFNSVL
460 470 480 490 500
PFLDLLSQTV SLAGTPGLHI PVRTEMVCKF LVQLSMDFSS YYNRVHILGE
510 520 530
PRPHLFGQMF ARLQLLRAVR EVFHTGLAML GLPPLSHI
Length:538
Mass (Da):58,733
Last modified:July 5, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i866BF4B5C115B3A4
GO
Isoform 2 (identifier: Q6PJN8-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-371: Missing.

Show »
Length:167
Mass (Da):18,635
Checksum:iA9AFB14BD0B96372
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0A6YWX9A0A0A6YWX9_MOUSE
DALR anticodon-binding domain-conta...
Dalrd3
193Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0A6YW92A0A0A6YW92_MOUSE
DALR anticodon-binding domain-conta...
Dalrd3
171Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0A6YXN1A0A0A6YXN1_MOUSE
DALR anticodon-binding domain-conta...
Dalrd3
49Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti517R → G in BAC24990 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0307471 – 371Missing in isoform 2. 1 PublicationAdd BLAST371

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK002439 mRNA Translation: BAC24990.1
AK003374 mRNA Translation: BAB22747.1
AK149963 mRNA Translation: BAE29197.1
AK169405 mRNA Translation: BAE41151.1
AK171818 mRNA Translation: BAE42679.1
BC013483 mRNA Translation: AAH13483.2

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS40769.1 [Q6PJN8-1]

NCBI Reference Sequences

More...
RefSeqi
NP_080654.3, NM_026378.3 [Q6PJN8-1]
XP_017169029.1, XM_017313540.1 [Q6PJN8-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000019183; ENSMUSP00000019183; ENSMUSG00000019039 [Q6PJN8-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
67789

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:67789

UCSC genome browser

More...
UCSCi
uc009rqi.1 mouse [Q6PJN8-1]

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK002439 mRNA Translation: BAC24990.1
AK003374 mRNA Translation: BAB22747.1
AK149963 mRNA Translation: BAE29197.1
AK169405 mRNA Translation: BAE41151.1
AK171818 mRNA Translation: BAE42679.1
BC013483 mRNA Translation: AAH13483.2
CCDSiCCDS40769.1 [Q6PJN8-1]
RefSeqiNP_080654.3, NM_026378.3 [Q6PJN8-1]
XP_017169029.1, XM_017313540.1 [Q6PJN8-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000019183

PTM databases

iPTMnetiQ6PJN8
PhosphoSitePlusiQ6PJN8

Proteomic databases

EPDiQ6PJN8
PaxDbiQ6PJN8
PeptideAtlasiQ6PJN8
PRIDEiQ6PJN8

Genome annotation databases

EnsembliENSMUST00000019183; ENSMUSP00000019183; ENSMUSG00000019039 [Q6PJN8-1]
GeneIDi67789
KEGGimmu:67789
UCSCiuc009rqi.1 mouse [Q6PJN8-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
55152
MGIiMGI:1915039 Dalrd3

Phylogenomic databases

eggNOGiKOG1195 Eukaryota
COG0018 LUCA
GeneTreeiENSGT00390000014621
HOGENOMiHOG000043068
InParanoidiQ6PJN8
OMAiRDPHMLT
PhylomeDBiQ6PJN8
TreeFamiTF325601

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Dalrd3 mouse

Protein Ontology

More...
PROi
PR:Q6PJN8
RNActiQ6PJN8 protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000019039 Expressed in 286 organ(s), highest expression level in cerebellum
ExpressionAtlasiQ6PJN8 baseline and differential
GenevisibleiQ6PJN8 MM

Family and domain databases

InterProiView protein in InterPro
IPR008909 DALR_anticod-bd
IPR037380 DALRD3
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR16043 PTHR16043, 1 hit
PfamiView protein in Pfam
PF05746 DALR_1, 1 hit
SMARTiView protein in SMART
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiDALD3_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6PJN8
Secondary accession number(s): Q8C1T1, Q9D1L6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 5, 2004
Last modified: December 11, 2019
This is version 116 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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