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Protein
Submitted name:

ITSN2 protein

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Calcium bindingi66 – 77PROSITE-ProRule annotationAdd BLAST12

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandCalciumPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
ITSN2 proteinImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PeptideAtlasiQ6PJ79
PRIDEiQ6PJ79

Structurei

3D structure databases

ProteinModelPortaliQ6PJ79
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini21 – 109EHInterPro annotationAdd BLAST89
Domaini53 – 88EF-handInterPro annotationAdd BLAST36
Domaini243 – 332EHInterPro annotationAdd BLAST90
Domaini276 – 311EF-handInterPro annotationAdd BLAST36

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili367 – 500Sequence analysisAdd BLAST134
Coiled coili508 – 549Sequence analysisAdd BLAST42

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG1029 Eukaryota
KOG4305 Eukaryota
COG5422 LUCA
HOGENOMiHOG000010175
HOVERGENiHBG052159

Family and domain databases

CDDicd00052 EH, 2 hits
InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
IPR000261 EH_dom
IPR027029 Intersectin-2
PANTHERiPTHR11216:SF29 PTHR11216:SF29, 1 hit
PfamiView protein in Pfam
PF12763 EF-hand_4, 2 hits
SMARTiView protein in SMART
SM00054 EFh, 2 hits
SM00027 EH, 2 hits
SUPFAMiSSF47473 SSF47473, 2 hits
PROSITEiView protein in PROSITE
PS00018 EF_HAND_1, 1 hit
PS50222 EF_HAND_2, 2 hits
PS50031 EH, 2 hits

Sequencei

Sequence statusi: Complete.

Q6PJ79-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQFPTAMNG GPNMWAITSE ERTKHDRQFD NLKPSGGYIT GDQARNFFLQ
60 70 80 90 100
SGLPAPVLAE IWALSDLNKD GKMDQQEFSI AMKLIKLKLQ GQQLPVVLPP
110 120 130 140 150
IMKQPPMFSP LISARFGMGS MPNLSIPQPL PPAAPITSLS SATSGTNLPP
160 170 180 190 200
LMMPTPLVPS VSTSSLPNGT ASLIQPLPIP YSSSTLPHGS SYSLMMGGFG
210 220 230 240 250
GASIQKAQSL IDLGSSSSTS STASLSGNSP KTGTSEWAVP QPTRLKYRQK
260 270 280 290 300
FNTLDKSMSG YLSGFQARNA LLQSNLSQTQ LATIWTLADI DGDGQLKAEE
310 320 330 340 350
FILAMHLTDM AKAGQPLPLT LPPELVPPSF RGGKQIDSIN GTLPSYQKMQ
360 370 380 390 400
EEEPQKKLPV TFEDKRKANY ERGNMELEKR RQALMEQQQR EAERKAQKEK
410 420 430 440 450
EEWERKQREL QEQEWKKQLE LEKRLEKQRE LERQREEERR KDIERREAAK
460 470 480 490 500
QELERQRRLE WERIRRQELL NQKNREQEEI VRLNSKKKNL HLELEALNGK
510 520 530 540 550
HQQISGRLQD VRLKKQTQKT ELEVLDKQCD LEIMEIKQLQ QELQEYQNKL
560
IYLVPEKQLL
Length:560
Mass (Da):63,669
Last modified:July 5, 2004 - v1
Checksum:i4F9518AC59D0EE49
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC020921 mRNA Translation: AAH20921.1
UniGeneiHs.432562

Similar proteinsi

Entry informationi

Entry nameiQ6PJ79_HUMAN
AccessioniPrimary (citable) accession number: Q6PJ79
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: July 18, 2018
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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