PIK3CB

Functionⁱ

GO - Molecular functionⁱ

kinase activity Source: UniProtKB-UniRule

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

phosphatidylinositol-mediated signaling Source: InterPro
phosphatidylinositol phosphorylation Source: InterPro

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	KinasePROSITE-ProRule annotationSAAS annotation, Transferase

Molecular function

KinasePROSITE-ProRule annotationSAAS annotation, Transferase

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: PIK3CB proteinImported
Gene namesⁱ	Name:PIK3CBImported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Subcellular locationⁱ

GO - Cellular component

PTM / Processingⁱ

Proteomic databases

PeptideAtlas More...PeptideAtlasⁱ	Q6PJ60

PeptideAtlasⁱ

Q6PJ60

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q6PJ60
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	1 – 119	PI3K/PI4KInterPro annotationAdd BLAST		119

Coiled coil

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Coiled coilⁱ	100 – 120	Sequence analysisAdd BLAST		21

Sequence similaritiesⁱ

Belongs to the PI3/PI4-kinase family.SAAS annotation

Keywords - Domainⁱ

Coiled coilSequence analysis

Phylogenomic databases

eggNOGⁱ	KOG0904 Eukaryota COG5032 LUCA
HOVERGENⁱ	HBG093740

Family and domain databases

Gene3Dⁱ	1.10.1070.11, 1 hit
InterProⁱ	View protein in InterPro IPR011009 Kinase-like_dom_sf IPR000403 PI3/4_kinase_cat_dom IPR036940 PI3/4_kinase_cat_sf IPR015433 PI_Kinase
PANTHERⁱ	PTHR10048 PTHR10048, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00454 PI3_PI4_kinase, 1 hit
SMARTⁱ	View protein in SMART SM00146 PI3Kc, 1 hit
SUPFAMⁱ	SSF56112 SSF56112, 1 hit
PROSITEⁱ	View protein in PROSITE PS50290 PI3_4_KINASE_3, 1 hit

Sequenceⁱ

Sequence statusⁱ: Fragment.

Q6PJ60-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
QLFHIDFGHI LGNFKSKFGI KRERVPFILT YDFIHVIQQG KTGNTEKFGR 
        60         70         80         90        100
FRQCCEDAYL ILRRHGNLFI TLFALMLTAG LPELTSVKDI QYLKDSLALG 
       110        120        130 
KSEEEALKQF KQKFDEALRE SWTTKVNWMA HTVRKDYRS

Length:139

Mass (Da):16,319

Last modified:July 5, 2004 - v1

Checksum:ⁱC6BB06B2E9C08891

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Non-terminal residueⁱ	1	Imported		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BC022049 mRNA Translation: AAH22049.1
UniGeneⁱ	Hs.239818

Protein	Similar proteins		Species	Score	Length	Source
Q6PJ60	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta		SAIBB		1091	UniRef90_A0A2K6SKL9
phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform-like		LEPWE		235
Uncharacterized protein (Fragment)		HUMAN		286
Putative phosphatidylinositol 3-kinase vps34 involved in signal transduction		DESRO		1092
UPI000787CAA1		ROUAE		1102
+7

Protein	Similar proteins		Species	Score	Length	Source
Q6PJ60	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit		GORGO		1041	UniRef50_G3R2C2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit		ODORO		946
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit		PIG		1013
Phosphatidylinositol 3-kinase catalytic subunit type 3		TURTR		1004
PIK3CB isoform 7 (Fragment)		PONAB		180
+49

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BC022049 mRNA Translation: AAH22049.1
UniGeneⁱ	Hs.239818

3D structure databases

ProteinModelPortalⁱ	Q6PJ60
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Proteomic databases

PeptideAtlasⁱ	Q6PJ60

PeptideAtlasⁱ

Q6PJ60

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Phylogenomic databases

eggNOGⁱ	KOG0904 Eukaryota COG5032 LUCA
HOVERGENⁱ	HBG093740

Miscellaneous databases

ChiTaRSⁱ	PIK3CB human

ChiTaRSⁱ

PIK3CB human

Family and domain databases

Gene3Dⁱ	1.10.1070.11, 1 hit
InterProⁱ	View protein in InterPro IPR011009 Kinase-like_dom_sf IPR000403 PI3/4_kinase_cat_dom IPR036940 PI3/4_kinase_cat_sf IPR015433 PI_Kinase
PANTHERⁱ	PTHR10048 PTHR10048, 1 hit
Pfamⁱ	View protein in Pfam PF00454 PI3_PI4_kinase, 1 hit
SMARTⁱ	View protein in SMART SM00146 PI3Kc, 1 hit
SUPFAMⁱ	SSF56112 SSF56112, 1 hit
PROSITEⁱ	View protein in PROSITE PS50290 PI3_4_KINASE_3, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q6PJ60_HUMAN
Accessionⁱ	Q6PJ60Primary (citable) accession number: Q6PJ60
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	July 5, 2004
	Last sequence update:	July 5, 2004
	Last modified:	November 7, 2018
	This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

UniProtKB - Q6PJ60 (Q6PJ60_HUMAN)

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PIK3CB protein

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Keywordsⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Other locations

PTM / Processingⁱ

Proteomic databases

Structureⁱ

3D structure databases

Family & Domainsⁱ

Domains and Repeats

Coiled coil

Sequence similaritiesⁱ

Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Experimental Info

Sequence databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Phylogenomic databases

Miscellaneous databases

Family and domain databases

Entry informationⁱ

UniProt is an ELIXIR core data resource

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UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q6PJ60 (Q6PJ60_HUMAN)

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PIK3CB protein

PIK3CB

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Other locations

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Coiled coil

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Experimental Info

Sequence databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Phylogenomic databases

Miscellaneous databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

UniProt is an ELIXIR core data resource

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

PTM / Processingⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ