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Entry version 134 (22 Apr 2020)
Sequence version 1 (05 Jul 2004)
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Protein

INO80 complex subunit C

Gene

INO80C

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processDNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-5689603 UCH proteinases
R-HSA-5696394 DNA Damage Recognition in GG-NER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
INO80 complex subunit C
Alternative name(s):
IES6 homolog
Short name:
hIes6
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:INO80C
Synonyms:C18orf37
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 18

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:26994 INO80C

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q6PI98

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000153391

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162392132

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q6PI98 Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
INO80C

Domain mapping of disease mutations (DMDM)

More...
DMDMi
68565181

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000793171 – 192INO80 complex subunit CAdd BLAST192

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q6PI98

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q6PI98

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q6PI98

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q6PI98

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q6PI98

PeptideAtlas

More...
PeptideAtlasi
Q6PI98

PRoteomics IDEntifications database

More...
PRIDEi
Q6PI98

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
19504
67147 [Q6PI98-1]
67148 [Q6PI98-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q6PI98

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q6PI98

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000153391 Expressed in testis and 200 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q6PI98 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q6PI98 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000153391 Tissue enhanced (testis)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the helicase ATP-binding and the helicase C-terminal domain of INO80.

Component of some MLL1/MLL complex, at least composed of the core components KMT2A/MLL1, ASH2L, HCFC1/HCF1, WDR5 and RBBP5, as well as the facultative components BAP18, CHD8, E2F6, HSP70, INO80C, KANSL1, LAS1L, MAX, MCRS1, MGA, MYST1/MOF, PELP1, PHF20, PRP31, RING2, RUVB1/TIP49A, RUVB2/TIP49B, SENP3, TAF1, TAF4, TAF6, TAF7, TAF9 and TEX10.

4 Publications

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
125928, 28 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-846 INO80 chromatin remodeling complex

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q6PI98

Protein interaction database and analysis system

More...
IntActi
Q6PI98, 19 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000467041

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q6PI98 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q6PI98

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000014303

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_071116_0_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q6PI98

KEGG Orthology (KO)

More...
KOi
K11667

Identification of Orthologs from Complete Genome Data

More...
OMAi
DNTFMHS

Database of Orthologous Groups

More...
OrthoDBi
1560268at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q6PI98

TreeFam database of animal gene trees

More...
TreeFami
TF323529

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR029525 INO80C/Ies6
IPR013272 Vps72/YL1_C

The PANTHER Classification System

More...
PANTHERi
PTHR31200 PTHR31200, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF08265 YL1_C, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00993 YL1_C, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 6 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q6PI98-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAAQIPIVAT TSTPGIVRNS KKRPASPSHN GSSGGGYGAS KKKKASASSF
60 70 80 90 100
AQGISMEAMS ENKMVPSEFS TGPVEKAAKP LPFKDPNFVH SGHGGAVAGK
110 120 130 140 150
KNRTWKNLKQ ILASERALPW QLNDPNYFSI DAPPSFKPAK KYSDVSGLLA
160 170 180 190
NYTDPQSKLR FSTIEEFSYI RRLPSDVVTG YLALRKATSI VP
Length:192
Mass (Da):20,643
Last modified:July 5, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6EED290EB9E4E68E
GO
Isoform 2 (identifier: Q6PI98-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     150-192: ANYTDPQSKL...ALRKATSIVP → EPPNCFPQRL...FIMAILVGVK

Show »
Length:197
Mass (Da):21,108
Checksum:i779928BE6DB701E0
GO
Isoform 3 (identifier: Q6PI98-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     52-52: Q → QTCLSPSTMIVRPPQPRGTTCLLPSAMIVRPPQPRGN

Show »
Length:228
Mass (Da):24,498
Checksum:i7B3654DA04302E6C
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
K7EQ79K7EQ79_HUMAN
INO80 complex subunit C
INO80C
95Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7EIY8K7EIY8_HUMAN
Chromosome 18 open reading frame 37...
INO80C C18orf37, hCG_2020980
137Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M0R3E2M0R3E2_HUMAN
INO80 complex subunit C
INO80C
136Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7ELX9K7ELX9_HUMAN
INO80 complex subunit C
INO80C
89Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7ENM4K7ENM4_HUMAN
INO80 complex subunit C
INO80C
98Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7EKI6K7EKI6_HUMAN
INO80 complex subunit C
INO80C
29Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti107N → Y in BAG62346 (PubMed:14702039).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_04496752Q → QTCLSPSTMIVRPPQPRGTT CLLPSAMIVRPPQPRGN in isoform 3. 1 Publication1
Alternative sequenceiVSP_014531150 – 192ANYTD…TSIVP → EPPNCFPQRLHQLTFPLAMD EGSNFSRCSPTLVNFGFVFI MAILVGVK in isoform 2. 1 PublicationAdd BLAST43

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK095502 mRNA Translation: BAC04560.1
AK300660 mRNA Translation: BAG62346.1
AC007998 Genomic DNA No translation available.
BC039404 mRNA Translation: AAH39404.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS11914.1 [Q6PI98-1]
CCDS45853.1 [Q6PI98-4]

NCBI Reference Sequences

More...
RefSeqi
NP_001092287.1, NM_001098817.1 [Q6PI98-4]
NP_919257.2, NM_194281.3 [Q6PI98-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000334598; ENSP00000334473; ENSG00000153391 [Q6PI98-1]
ENST00000441607; ENSP00000391457; ENSG00000153391 [Q6PI98-4]
ENST00000592173; ENSP00000465273; ENSG00000153391 [Q6PI98-3]

Database of genes from NCBI RefSeq genomes

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GeneIDi
125476

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:125476

UCSC genome browser

More...
UCSCi
uc002kyw.2 human [Q6PI98-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK095502 mRNA Translation: BAC04560.1
AK300660 mRNA Translation: BAG62346.1
AC007998 Genomic DNA No translation available.
BC039404 mRNA Translation: AAH39404.1
CCDSiCCDS11914.1 [Q6PI98-1]
CCDS45853.1 [Q6PI98-4]
RefSeqiNP_001092287.1, NM_001098817.1 [Q6PI98-4]
NP_919257.2, NM_194281.3 [Q6PI98-1]

3D structure databases

SMRiQ6PI98
ModBaseiSearch...

Protein-protein interaction databases

BioGridi125928, 28 interactors
ComplexPortaliCPX-846 INO80 chromatin remodeling complex
CORUMiQ6PI98
IntActiQ6PI98, 19 interactors
STRINGi9606.ENSP00000467041

PTM databases

iPTMnetiQ6PI98
PhosphoSitePlusiQ6PI98

Polymorphism and mutation databases

BioMutaiINO80C
DMDMi68565181

Proteomic databases

EPDiQ6PI98
jPOSTiQ6PI98
MassIVEiQ6PI98
MaxQBiQ6PI98
PaxDbiQ6PI98
PeptideAtlasiQ6PI98
PRIDEiQ6PI98
ProteomicsDBi19504
67147 [Q6PI98-1]
67148 [Q6PI98-3]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
62486 26 antibodies

Genome annotation databases

EnsembliENST00000334598; ENSP00000334473; ENSG00000153391 [Q6PI98-1]
ENST00000441607; ENSP00000391457; ENSG00000153391 [Q6PI98-4]
ENST00000592173; ENSP00000465273; ENSG00000153391 [Q6PI98-3]
GeneIDi125476
KEGGihsa:125476
UCSCiuc002kyw.2 human [Q6PI98-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
125476

GeneCards: human genes, protein and diseases

More...
GeneCardsi
INO80C
HGNCiHGNC:26994 INO80C
HPAiENSG00000153391 Tissue enhanced (testis)
neXtProtiNX_Q6PI98
OpenTargetsiENSG00000153391
PharmGKBiPA162392132

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

GeneTreeiENSGT00390000014303
HOGENOMiCLU_071116_0_1_1
InParanoidiQ6PI98
KOiK11667
OMAiDNTFMHS
OrthoDBi1560268at2759
PhylomeDBiQ6PI98
TreeFamiTF323529

Enzyme and pathway databases

ReactomeiR-HSA-5689603 UCH proteinases
R-HSA-5696394 DNA Damage Recognition in GG-NER

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
INO80C human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
125476
PharosiQ6PI98 Tdark

Protein Ontology

More...
PROi
PR:Q6PI98
RNActiQ6PI98 protein

Gene expression databases

BgeeiENSG00000153391 Expressed in testis and 200 other tissues
ExpressionAtlasiQ6PI98 baseline and differential
GenevisibleiQ6PI98 HS

Family and domain databases

InterProiView protein in InterPro
IPR029525 INO80C/Ies6
IPR013272 Vps72/YL1_C
PANTHERiPTHR31200 PTHR31200, 1 hit
PfamiView protein in Pfam
PF08265 YL1_C, 1 hit
SMARTiView protein in SMART
SM00993 YL1_C, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiIN80C_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6PI98
Secondary accession number(s): B4DUI4
, E9PCS7, Q86WR1, Q8N994
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 5, 2005
Last sequence update: July 5, 2004
Last modified: April 22, 2020
This is version 134 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 18
    Human chromosome 18: entries, gene names and cross-references to MIM
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