UniProtKB - Q6PH81 (CP087_HUMAN)
Protein
UPF0547 protein C16orf87
Gene
C16orf87
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Recommended name: UPF0547 protein C16orf87 |
Gene namesi | Name:C16orf87 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000155330.9 |
HGNCi | HGNC:33754, C16orf87 |
neXtProti | NX_Q6PH81 |
Pathology & Biotechi
Organism-specific databases
DisGeNETi | 388272 |
OpenTargetsi | ENSG00000155330 |
PharmGKBi | PA162378458 |
Miscellaneous databases
Pharosi | Q6PH81, Tdark |
Polymorphism and mutation databases
BioMutai | C16orf87 |
DMDMi | 74737667 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000326521 | 1 – 154 | UPF0547 protein C16orf87Add BLAST | 154 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 91 | PhosphoserineCombined sources | 1 |
Keywords - PTMi
PhosphoproteinProteomic databases
EPDi | Q6PH81 |
jPOSTi | Q6PH81 |
MassIVEi | Q6PH81 |
MaxQBi | Q6PH81 |
PaxDbi | Q6PH81 |
PeptideAtlasi | Q6PH81 |
PRIDEi | Q6PH81 |
ProteomicsDBi | 67121 [Q6PH81-1] 67122 [Q6PH81-2] |
PTM databases
iPTMneti | Q6PH81 |
PhosphoSitePlusi | Q6PH81 |
Expressioni
Gene expression databases
Bgeei | ENSG00000155330, Expressed in prostate gland and 197 other tissues |
ExpressionAtlasi | Q6PH81, baseline and differential |
Genevisiblei | Q6PH81, HS |
Organism-specific databases
HPAi | ENSG00000155330, Low tissue specificity |
Interactioni
Binary interactionsi
Hide detailsQ6PH81
With | #Exp. | IntAct |
---|---|---|
HDAC1 [Q13547] | 4 | EBI-6598617,EBI-301834 |
MAGEA12 [P43365] | 6 | EBI-6598617,EBI-749530 |
SRRM4 [A7MD48] | 3 | EBI-6598617,EBI-3867173 |
Protein-protein interaction databases
BioGRIDi | 132622, 26 interactors |
IntActi | Q6PH81, 22 interactors |
STRINGi | 9606.ENSP00000285697 |
Miscellaneous databases
RNActi | Q6PH81, protein |
Family & Domainsi
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 104 – 132 | Sequence analysisAdd BLAST | 29 |
Sequence similaritiesi
Belongs to the UPF0547 family.Curated
Keywords - Domaini
Coiled coilPhylogenomic databases
eggNOGi | ENOG502RY8J, Eukaryota |
GeneTreei | ENSGT00390000009505 |
HOGENOMi | CLU_2399051_0_0_1 |
InParanoidi | Q6PH81 |
OMAi | STNDMEN |
OrthoDBi | 1563136at2759 |
PhylomeDBi | Q6PH81 |
TreeFami | TF331719 |
Family and domain databases
InterProi | View protein in InterPro IPR040246, C16orf87-like IPR018886, UPF0547 |
PANTHERi | PTHR31101, PTHR31101, 1 hit |
Pfami | View protein in Pfam PF10571, UPF0547, 1 hit |
s (2+)i Sequence
Sequence statusi: Complete.
This entry describes 2 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All
Isoform 1 (identifier: Q6PH81-1) [UniParc]FASTAAdd to basket
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MSATRAKKVK MATKSCPECD QQVPVACKSC PCGYIFISRK LLNAKHSEKS
60 70 80 90 100
PPSTENKHEA KRRRTERVRR EKINSTVNKD LENRKRSRSN SHSDHIRRGR
110 120 130 140 150
GRPKSASAKK HEEEREKQEK EIDIYANLSD EKAFVFSVAL AEINRKIINQ
RLIL
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketH3BQL3 | H3BQL3_HUMAN | UPF0547 protein C16orf87 | C16orf87 | 161 | Annotation score: |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_032670 | 55 – 115 | Missing in isoform 2. 1 PublicationAdd BLAST | 61 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX647945 mRNA Translation: CAH56192.1 CH471092 Genomic DNA Translation: EAW82689.1 BC056676 mRNA Translation: AAH56676.1 |
CCDSi | CCDS10724.1 [Q6PH81-1] CCDS86522.1 [Q6PH81-2] |
RefSeqi | NP_001001436.1, NM_001001436.3 [Q6PH81-1] NP_001335589.1, NM_001348660.1 [Q6PH81-2] |
Genome annotation databases
Ensembli | ENST00000285697; ENSP00000285697; ENSG00000155330 [Q6PH81-1] ENST00000394806; ENSP00000378285; ENSG00000155330 [Q6PH81-2] |
GeneIDi | 388272 |
KEGGi | hsa:388272 |
UCSCi | uc002eek.2, human [Q6PH81-1] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX647945 mRNA Translation: CAH56192.1 CH471092 Genomic DNA Translation: EAW82689.1 BC056676 mRNA Translation: AAH56676.1 |
CCDSi | CCDS10724.1 [Q6PH81-1] CCDS86522.1 [Q6PH81-2] |
RefSeqi | NP_001001436.1, NM_001001436.3 [Q6PH81-1] NP_001335589.1, NM_001348660.1 [Q6PH81-2] |
3D structure databases
SMRi | Q6PH81 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 132622, 26 interactors |
IntActi | Q6PH81, 22 interactors |
STRINGi | 9606.ENSP00000285697 |
PTM databases
iPTMneti | Q6PH81 |
PhosphoSitePlusi | Q6PH81 |
Polymorphism and mutation databases
BioMutai | C16orf87 |
DMDMi | 74737667 |
Proteomic databases
EPDi | Q6PH81 |
jPOSTi | Q6PH81 |
MassIVEi | Q6PH81 |
MaxQBi | Q6PH81 |
PaxDbi | Q6PH81 |
PeptideAtlasi | Q6PH81 |
PRIDEi | Q6PH81 |
ProteomicsDBi | 67121 [Q6PH81-1] 67122 [Q6PH81-2] |
Protocols and materials databases
Antibodypediai | 52031, 45 antibodies |
DNASUi | 388272 |
Genome annotation databases
Ensembli | ENST00000285697; ENSP00000285697; ENSG00000155330 [Q6PH81-1] ENST00000394806; ENSP00000378285; ENSG00000155330 [Q6PH81-2] |
GeneIDi | 388272 |
KEGGi | hsa:388272 |
UCSCi | uc002eek.2, human [Q6PH81-1] |
Organism-specific databases
CTDi | 388272 |
DisGeNETi | 388272 |
EuPathDBi | HostDB:ENSG00000155330.9 |
GeneCardsi | C16orf87 |
HGNCi | HGNC:33754, C16orf87 |
HPAi | ENSG00000155330, Low tissue specificity |
neXtProti | NX_Q6PH81 |
OpenTargetsi | ENSG00000155330 |
PharmGKBi | PA162378458 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | ENOG502RY8J, Eukaryota |
GeneTreei | ENSGT00390000009505 |
HOGENOMi | CLU_2399051_0_0_1 |
InParanoidi | Q6PH81 |
OMAi | STNDMEN |
OrthoDBi | 1563136at2759 |
PhylomeDBi | Q6PH81 |
TreeFami | TF331719 |
Enzyme and pathway databases
PathwayCommonsi | Q6PH81 |
Miscellaneous databases
BioGRID-ORCSi | 388272, 10 hits in 836 CRISPR screens |
ChiTaRSi | C16orf87, human |
GenomeRNAii | 388272 |
Pharosi | Q6PH81, Tdark |
PROi | PR:Q6PH81 |
RNActi | Q6PH81, protein |
Gene expression databases
Bgeei | ENSG00000155330, Expressed in prostate gland and 197 other tissues |
ExpressionAtlasi | Q6PH81, baseline and differential |
Genevisiblei | Q6PH81, HS |
Family and domain databases
InterProi | View protein in InterPro IPR040246, C16orf87-like IPR018886, UPF0547 |
PANTHERi | PTHR31101, PTHR31101, 1 hit |
Pfami | View protein in Pfam PF10571, UPF0547, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | CP087_HUMAN | |
Accessioni | Q6PH81Primary (citable) accession number: Q6PH81 Secondary accession number(s): Q63HN9 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 8, 2008 |
Last sequence update: | July 5, 2004 | |
Last modified: | December 2, 2020 | |
This is version 127 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Uncharacterized protein families (UPF)
List of uncharacterized protein family (UPF) entries - SIMILARITY comments
Index of protein domains and families - Human chromosome 16
Human chromosome 16: entries, gene names and cross-references to MIM