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UniProtKB - Q6PGR4 (Q6PGR4_HUMAN)
Protein
Submitted name:
NCOR1 protein
Gene
NCOR1
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: NCOR1 proteinImported |
Gene namesi | Name:NCOR1Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 435 – 486 | SANTInterPro annotationAdd BLAST | 52 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 177 | DisorderedSequence analysisAdd BLAST | 177 | |
Regioni | 206 – 231 | DisorderedSequence analysisAdd BLAST | 26 | |
Regioni | 497 – 518 | DisorderedSequence analysisAdd BLAST | 22 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 308 – 328 | Sequence analysisAdd BLAST | 21 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1 – 39 | Polar residuesSequence analysisAdd BLAST | 39 | |
Compositional biasi | 47 – 69 | Polar residuesSequence analysisAdd BLAST | 23 | |
Compositional biasi | 100 – 115 | Basic and acidic residuesSequence analysisAdd BLAST | 16 | |
Compositional biasi | 162 – 177 | Polar residuesSequence analysisAdd BLAST | 16 | |
Compositional biasi | 504 – 518 | Basic and acidic residuesSequence analysisAdd BLAST | 15 |
Sequence similaritiesi
Belongs to the N-CoR nuclear receptor corepressors family.ARBA annotation
Keywords - Domaini
Coiled coilSequence analysisARBA annotationPhylogenomic databases
OrthoDBi | 1554997at2759 |
Family and domain databases
CDDi | cd00167, SANT, 1 hit |
InterProi | View protein in InterPro IPR009057, Homeobox-like_sf IPR031557, N-CoR_GPS2_interact IPR001005, SANT/Myb IPR017884, SANT_dom |
Pfami | View protein in Pfam PF15784, GPS2_interact, 1 hit |
SMARTi | View protein in SMART SM00717, SANT, 1 hit |
SUPFAMi | SSF46689, SSF46689, 1 hit |
PROSITEi | View protein in PROSITE PS51293, SANT, 1 hit |
i Sequence
Sequence statusi: Fragment.
Q6PGR4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSSSGYPPNQ GAFSTEQSRY PPHSVQYTFP NTRHQQEFAV PDYRSSHLEV
60 70 80 90 100
SQASQLLQQQ QQQQLRRRPS LLSEFHPGSD RPQERRTSYE PFHPGPSPVD
110 120 130 140 150
HDSLESKRPR LEQVSDSHFQ RVSAAVLPLV HPLPEGLRAS ADAKKDPAFG
160 170 180 190 200
GKHEAPSSPI SGQPCGDDQN ASPSKLSKEE LIQSMDRVDR EIAKVEQQIL
210 220 230 240 250
KLKKKQQQLE EEAAKPPEPE KPVSPPPVEQ KHRSIVQIIY DENRKKAEEA
260 270 280 290 300
HKIFEGLGPK VELPLYNQPS DTKVYHENIK TNQVMRKKLI LFFKRRNHAR
310 320 330 340 350
KQREQKICQR YDQLMEAWEK KVDRIENNPR RKAKESKTRE YYEKQFPEIR
360 370 380 390 400
KQREQQERFQ RVGQRGAGLS ATIARSEHEI SEIIDGLSEQ ENNEKQMRQL
410 420 430 440 450
SVIPPMMFDA EQRRVKFINM NGLMEDPMKV YKDRQFMNVW TDHEKEIFKD
460 470 480 490 500
KFIQHPKNFG LIASYLERKS VPDCVLYYYL TKKNENYKAL VRRNYGKRRG
510
RNQQIARPSQ EEKVKKKK
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 518 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC056862 mRNA Translation: AAH56862.1 |
RefSeqi | NP_001177367.1, NM_001190438.1 NP_001177369.1, NM_001190440.1 |
Genome annotation databases
GeneIDi | 9611 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC056862 mRNA Translation: AAH56862.1 |
RefSeqi | NP_001177367.1, NM_001190438.1 NP_001177369.1, NM_001190440.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | Q6PGR4 |
Protocols and materials databases
DNASUi | 9611 |
Genome annotation databases
GeneIDi | 9611 |
Organism-specific databases
CTDi | 9611 |
Phylogenomic databases
OrthoDBi | 1554997at2759 |
Miscellaneous databases
BioGRID-ORCSi | 9611, 57 hits in 1121 CRISPR screens |
ChiTaRSi | NCOR1, human |
GenomeRNAii | 9611 |
Gene expression databases
Genevisiblei | Q6PGR4, HS |
Family and domain databases
CDDi | cd00167, SANT, 1 hit |
InterProi | View protein in InterPro IPR009057, Homeobox-like_sf IPR031557, N-CoR_GPS2_interact IPR001005, SANT/Myb IPR017884, SANT_dom |
Pfami | View protein in Pfam PF15784, GPS2_interact, 1 hit |
SMARTi | View protein in SMART SM00717, SANT, 1 hit |
SUPFAMi | SSF46689, SSF46689, 1 hit |
PROSITEi | View protein in PROSITE PS51293, SANT, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Q6PGR4_HUMAN | |
Accessioni | Q6PGR4Primary (citable) accession number: Q6PGR4 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 5, 2004 |
Last sequence update: | July 5, 2004 | |
Last modified: | May 25, 2022 | |
This is version 100 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |