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UniProtKB - Q6PGF5 (Q6PGF5_MOUSE)

Entry version 131 (19 Jan 2022)
Sequence version 1 (05 Jul 2004)
Previous versions | rss
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Protein
Submitted name:

BMS1 homolog, ribosome assembly protein (Yeast)

Gene

Bms1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processRibosome biogenesisARBA annotation

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-MMU-6791226, Major pathway of rRNA processing in the nucleolus and cytosol

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
BMS1 homolog, ribosome assembly protein (Yeast)Imported
Submitted name:
BMS1, ribosome biogenesis factorImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Bms1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...MGIi		MGI:2446132, Bms1

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSMUSG00000030138

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

NucleusARBA annotation

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		335372

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSMUSG00000030138, Expressed in primary oocyte and 312 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...IntActi		Q6PGF5, 1 interactor

STRING: functional protein association networks

More...STRINGi		10090.ENSMUSP00000032237

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini80 – 245Bms1-type GInterPro annotationAdd BLAST166

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 42DisorderedSequence analysisAdd BLAST42
Regioni399 – 665DisorderedSequence analysisAdd BLAST267
Regioni783 – 829DisorderedSequence analysisAdd BLAST47
Regioni1224 – 1284DisorderedSequence analysisAdd BLAST61

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1 – 20Basic residuesSequence analysisAdd BLAST20
Compositional biasi21 – 42Basic and acidic residuesSequence analysisAdd BLAST22
Compositional biasi412 – 438Basic and acidic residuesSequence analysisAdd BLAST27
Compositional biasi439 – 476Acidic residuesSequence analysisAdd BLAST38
Compositional biasi516 – 533Acidic residuesSequence analysisAdd BLAST18
Compositional biasi595 – 609Acidic residuesSequence analysisAdd BLAST15
Compositional biasi610 – 625Basic and acidic residuesSequence analysisAdd BLAST16
Compositional biasi642 – 659Basic and acidic residuesSequence analysisAdd BLAST18
Compositional biasi788 – 804Basic and acidic residuesSequence analysisAdd BLAST17
Compositional biasi1236 – 1284Basic and acidic residuesSequence analysisAdd BLAST49

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1951, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000153195

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_002486_0_1_1

Identification of Orthologs from Complete Genome Data

More...OMAi		QMEQQEF

Database of Orthologous Groups

More...OrthoDBi		463678at2759

TreeFam database of animal gene trees

More...TreeFami		TF105751

Family and domain databases

Conserved Domains Database

More...CDDi		cd01882, BMS1, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.40.50.300, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR012948, AARP2CN
IPR039761, Bms1/Tsr1
IPR037875, Bms1_N
IPR007034, BMS1_TSR1_C
IPR030387, G_Bms1/Tsr1_dom
IPR027417, P-loop_NTPase

The PANTHER Classification System

More...PANTHERi		PTHR12858, PTHR12858, 2 hits

Pfam protein domain database

More...Pfami		View protein in Pfam
PF08142, AARP2CN, 1 hit
PF04950, RIBIOP_C, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00785, AARP2CN, 1 hit
SM01362, DUF663, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF52540, SSF52540, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51714, G_BMS1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q6PGF5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
METKDHKKHR KKHSGPKAEK KKKRHLQDLQ LGDEEDARKR NPKAFAVQSA 
        60         70         80         90        100
VRMARSFHRT QDLKTKKHHI PVVDRTPLEP PPIVVVVMGP PKVGKSTLIR 
       110        120        130        140        150
CLIRNFTRQK LSEIRGPVTI VSGKKRRLTI IECGCDINVM IDLAKVADLV 
       160        170        180        190        200
LMLIDASFGF EMETFEFLNI CQVHGFPKIM GVLTHLDSFK HNKQLKKTKK 
       210        220        230        240        250
RLKHRFWTEV YPGAKLFYLS GMVHGEYQNQ EIHNLGRFIT VMKFRPLTWQ 
       260        270        280        290        300
TSHPYILADR MEDLTNPEAI RTNVKCDRKV SLYGYLRGAY LKNNSQIHMP 
       310        320        330        340        350
GVGDFVASDV SFLPDPCALP EQQKKRCLNE KEKLVYAPLS GVGGVLYDKD 
       360        370        380        390        400
AVYVDLGGSH GFQAAEETGP THELVQSLIS THASIDAKMA SSRVTLFSDS 
       410        420        430        440        450
KPLGSEDIDN QGLWMPKEEK QVDVETGRVR RKAIFGDTED ESGDEESEDE 
       460        470        480        490        500
EDMSEADGME PGSSDDEAEE AEEEGAESSS GNYMMGRGRK RPKLEEQEED 
       510        520        530        540        550
SEADSPAFAD SDDDLERSSG GEEEAEEADE SSADGASTGE RDAGECGSVG 
       560        570        580        590        600
EASEESPSAA HQWRPHADAQ KPSPVRKAAL TTSDSGHCTA EEAFPSEDES 
       610        620        630        640        650
EDSELSAEEE DSDHREVRGK LAHPLRDSGQ KPASESLVDE TSDIESLLKE 
       660        670        680        690        700
EEEYKEDNSS SVETSGALKW KEDLSRKAAE AFLRQQQAAP NLRKLIYGTV 
       710        720        730        740        750
TEDNEDEDGD PAEELGGLFH VSQPDRGCKH KADSLDCSRF PVEAPHDWDL 
       760        770        780        790        800
EEVMNSIRDC FVTGKWEDDK DAAKILAEEE ELYGDFEDLE TGDVHKGKPG 
       810        820        830        840        850
PDTQSEDIEE EEVKEETDPS EEESARKKHL DKKRKLKELF DAEYDEGEST 
       860        870        880        890        900
YFDDLKGEMQ RQAQLNQAEF EDQEDETRVQ YEGFRPGMYV RIEIENIPCE 
       910        920        930        940        950
FVQNFDPHYP IILGGLGNSE GTVGYVQMRI KKHRWYKKIL KSRDPIIFSV 
       960        970        980        990       1000
GWRRFQTIPL YYIEDHNGRQ RLLKYTPQHM HCGATFWGPI TPQGTGFLAI 
      1010       1020       1030       1040       1050
QSVSGVMPEF RIAATGVVLD LDKSIKIVKK LKLTGFPFKI FKNTSFIKGM 
      1060       1070       1080       1090       1100
FNSALEVAKF EGAVIRTVSG IRGQIKKALR APEGAFRASF EDKLLMSDIV 
      1110       1120       1130       1140       1150
FMRTWYPVSI PAFYNPVTSL LKPVGEKDTW SGMRTTHQLR LAHGIKLKAN 
      1160       1170       1180       1190       1200
KDSLYKPILR QKKHFNSLHI PKALQKALPF KNKPKTQAKA GKVPRDRQRP 
      1210       1220       1230       1240       1250
AVIREPHERK VLALLDALST IHSQKMKKAK EQRRLHNKEH VKMKQKEEED 
      1260       1270       1280 
KLRRQKDLRK KLFRMQGQKE KRSQKSSLRG AEDT
Length:1,284
Mass (Da):145,414
Last modified:July 5, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i55C8EF135F8F8B28
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
BC057054 mRNA Translation: AAH57054.1

NCBI Reference Sequences

More...RefSeqi		NP_919320.1, NM_194339.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSMUST00000032237; ENSMUSP00000032237; ENSMUSG00000030138

Database of genes from NCBI RefSeq genomes

More...GeneIDi		213895

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		mmu:213895

UCSC genome browser

More...UCSCi		uc009dlo.1, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC057054 mRNA Translation: AAH57054.1
RefSeqiNP_919320.1, NM_194339.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

IntActiQ6PGF5, 1 interactor
STRINGi10090.ENSMUSP00000032237

Proteomic databases

ProteomicsDBi335372

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		13377, 75 antibodies from 23 providers

The DNASU plasmid repository

More...DNASUi		213895

Genome annotation databases

EnsembliENSMUST00000032237; ENSMUSP00000032237; ENSMUSG00000030138
GeneIDi213895
KEGGimmu:213895
UCSCiuc009dlo.1, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		9790
MGIiMGI:2446132, Bms1
VEuPathDBiHostDB:ENSMUSG00000030138

Phylogenomic databases

eggNOGiKOG1951, Eukaryota
GeneTreeiENSGT00940000153195
HOGENOMiCLU_002486_0_1_1
OMAiQMEQQEF
OrthoDBi463678at2759
TreeFamiTF105751

Enzyme and pathway databases

ReactomeiR-MMU-6791226, Major pathway of rRNA processing in the nucleolus and cytosol

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		213895, 24 hits in 64 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		Bms1, mouse

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSMUSG00000030138, Expressed in primary oocyte and 312 other tissues

Family and domain databases

CDDicd01882, BMS1, 1 hit
Gene3Di3.40.50.300, 1 hit
InterProiView protein in InterPro
IPR012948, AARP2CN
IPR039761, Bms1/Tsr1
IPR037875, Bms1_N
IPR007034, BMS1_TSR1_C
IPR030387, G_Bms1/Tsr1_dom
IPR027417, P-loop_NTPase
PANTHERiPTHR12858, PTHR12858, 2 hits
PfamiView protein in Pfam
PF08142, AARP2CN, 1 hit
PF04950, RIBIOP_C, 1 hit
SMARTiView protein in SMART
SM00785, AARP2CN, 1 hit
SM01362, DUF663, 1 hit
SUPFAMiSSF52540, SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS51714, G_BMS1, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ6PGF5_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6PGF5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: January 19, 2022
This is version 131 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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