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Entry version 98 (07 Apr 2021)
Sequence version 1 (05 Jul 2004)
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Protein

Holliday junction recognition protein

Gene

Hjurp

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. Prevents CENPA-H4 tetramerization and prevents premature DNA binding by the CENPA-H4 tetramer. Directly binds Holliday junctions.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionChaperone, DNA-binding
Biological processCell cycle

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-606279, Deposition of new CENPA-containing nucleosomes at the centromere

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Holliday junction recognition protein
Alternative name(s):
Fetal liver expressing gene 1 protein homolog
Short name:
mFleg1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Hjurp
Synonyms:Fleg1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2685821, Hjurp

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Centromere, Chromosome, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003781541 – 667Holliday junction recognition proteinAdd BLAST667

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei169PhosphoserineBy similarity1
Modified residuei185PhosphoserineBy similarity1
Modified residuei195PhosphoserineBy similarity1
Modified residuei388PhosphoserineCombined sources1
Modified residuei424PhosphoserineBy similarity1
Modified residuei449PhosphoserineBy similarity1
Modified residuei462PhosphoserineBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki554Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei567PhosphoserineBy similarity1
Modified residuei613PhosphoserineBy similarity1

Keywords - PTMi

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q6PG16

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q6PG16

PRoteomics IDEntifications database

More...
PRIDEi
Q6PG16

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
273143 [Q6PG16-1]
273144 [Q6PG16-2]
273145 [Q6PG16-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q6PG16

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q6PG16

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with CENPA (via CATD domain); the interaction is direct and specific for CENPA since it does not interact with H3.1- or H3.3-containing nucleosomes. Heterotrimer composed of HJURP, CENPA and histone H4, where HJURP interacts with the dimer formed by CENPA and histone H4 and prevents tetramerization of CENPA and H4.

Identified in a centromere complex containing histones H2A, H2B and H4, and at least CENPA, CENPB, CENPC, CENPT, CENPN, HJURP, SUPT16H, SSRP1 and RSF1.

Interacts with 14-3-3 family members in a phosphorylation-dependent manner.

Interacts with MSH5 and NBN.

By similarity

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
237854, 3 interactors

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000054263

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q6PG16, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q6PG16

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502SJZT, Eukaryota

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q6PG16

Database of Orthologous Groups

More...
OrthoDBi
426984at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q6PG16

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR021052, HJURP
IPR022102, HJURP_C
IPR018465, Scm3/HJURP

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12347, HJURP_C, 2 hits
PF12346, HJURP_mid, 1 hit
PF10384, Scm3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q6PG16-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MESMGRQDRR LHQQLKESSS RFQTLMKRLI AKYNQPFEDD PLVEMRTLTY
60 70 80 90 100
ETPQGLRVWG GKLMKKEDKE YTQVIDRLNG QAPEGDSESS GADTSLEENW
110 120 130 140 150
PSCSSAMREA SGDPRQRQPA VPGNTLETDL RRKYLTQVDI LPQDEEYFKN
160 170 180 190 200
AEKRGGKDTV MTWVPSVTSS VTPASGCQDA ISAKSSGGPE VSALSSRGQG
210 220 230 240 250
PSYPCPADMA IVARSDGLSL LGTSSNSVSS QSFEVDDLCN VTISDLYEGM
260 270 280 290 300
MHSMSRLLRS KPSCIISTKT YINQSWKLRR RPSRKQGLHK NRTHCPRSKP
310 320 330 340 350
SQRSARKGPA SCSEPGKEAG ILRDYGNLLH VAPHKTGLEL KSVSLEGSKR
360 370 380 390 400
QVHKSSPAWK ELQMMPQKDL DLNRERENRV MTLQWLISPV KVVPRPRMLP
410 420 430 440 450
SQVEKWYREI KIKFDKLHQE YCLSSGKQPR LTDPTESWAV DVYRSGSKSP
460 470 480 490 500
GSRQDVETCR PSSPFGREKT ERPGEALEDL RGNGKSVKTK SCLLRSCPSP
510 520 530 540 550
EGSPSRSPSH SQLSSGLQEH NSEPTGKAVW PSTAISAPSI GSPGCGKDNY
560 570 580 590 600
YELKKEFNRL YQKYCLSPQR AKVTSCGRVS PMKAAAALPC QSEHLKRLNP
610 620 630 640 650
DSPQQSSQKR SISPGCHRRV LQDSTAQTAS TLVRDSWLPT KRCKLSYPVA
660
CAHQAKFHDT SGASGWP
Length:667
Mass (Da):74,199
Last modified:July 5, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i258747B28A1123C9
GO
Isoform 2 (identifier: Q6PG16-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     286-302: Missing.

Show »
Length:650
Mass (Da):72,243
Checksum:i2F5259C4C49B91B1
GO
Isoform 3 (identifier: Q6PG16-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     74-149: Missing.

Show »
Length:591
Mass (Da):65,763
Checksum:iC0F34D5D7552D7A3
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9QKG8E9QKG8_MOUSE
Holliday junction recognition prote...
Hjurp
667Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9Q4T0E9Q4T0_MOUSE
Holliday junction recognition prote...
Hjurp
591Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6RI36D6RI36_MOUSE
Holliday junction recognition prote...
Hjurp
89Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6XR06F6XR06_MOUSE
Holliday junction recognition prote...
Hjurp
76Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti12H → Q in BAC31301 (PubMed:16141072).Curated1
Sequence conflicti12H → Q in AAI31920 (PubMed:15489334).Curated1
Sequence conflicti16K → N in BAC31301 (PubMed:16141072).Curated1
Sequence conflicti16K → N in AAI31920 (PubMed:15489334).Curated1
Sequence conflicti19S → R in BAC31301 (PubMed:16141072).Curated1
Sequence conflicti19S → R in AAI31920 (PubMed:15489334).Curated1
Sequence conflicti46R → T in BAC31301 (PubMed:16141072).Curated1
Sequence conflicti46R → T in AAI31920 (PubMed:15489334).Curated1
Sequence conflicti190E → G in BAC31301 (PubMed:16141072).Curated1
Sequence conflicti190E → G in AAI31920 (PubMed:15489334).Curated1
Sequence conflicti245D → N in BAC31301 (PubMed:16141072).Curated1
Sequence conflicti245D → N in AAI31920 (PubMed:15489334).Curated1
Sequence conflicti262P → L in BAC31301 (PubMed:16141072).Curated1
Sequence conflicti262P → L in AAI31920 (PubMed:15489334).Curated1
Sequence conflicti315P → H in BAC31301 (PubMed:16141072).Curated1
Sequence conflicti315P → H in AAI31920 (PubMed:15489334).Curated1
Sequence conflicti355S → F in BAC31301 (PubMed:16141072).Curated1
Sequence conflicti355S → F in AAI31920 (PubMed:15489334).Curated1
Sequence conflicti380V → G in BAC31301 (PubMed:16141072).Curated1
Sequence conflicti380V → G in AAI31920 (PubMed:15489334).Curated1
Sequence conflicti539S → C in BAC31301 (PubMed:16141072).Curated1
Sequence conflicti539S → C in AAI31920 (PubMed:15489334).Curated1
Sequence conflicti551Y → D in BAD36742 (Ref. 1) Curated1
Sequence conflicti551Y → D in BAC31301 (PubMed:16141072).Curated1
Sequence conflicti551Y → D in AAI31920 (PubMed:15489334).Curated1
Sequence conflicti626A → P in BAC31301 (PubMed:16141072).Curated1
Sequence conflicti626A → P in AAI31920 (PubMed:15489334).Curated1
Sequence conflicti635 – 636DS → EP in BAC31301 (PubMed:16141072).Curated2
Sequence conflicti635 – 636DS → EP in AAI31920 (PubMed:15489334).Curated2
Sequence conflicti643C → R in BAC31301 (PubMed:16141072).Curated1
Sequence conflicti643C → R in AAI31920 (PubMed:15489334).Curated1
Sequence conflicti657 – 659FHD → SHN in BAC31301 (PubMed:16141072).Curated3
Sequence conflicti657 – 659FHD → SHN in AAI31920 (PubMed:15489334).Curated3

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_03751574 – 149Missing in isoform 3. 2 PublicationsAdd BLAST76
Alternative sequenceiVSP_037516286 – 302Missing in isoform 2. 1 PublicationAdd BLAST17

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB162219 mRNA Translation: BAD36742.1
AK042589 mRNA Translation: BAC31301.1
BC057309 mRNA Translation: AAH57309.1
BC131919 mRNA Translation: AAI31920.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS15144.1 [Q6PG16-1]

NCBI Reference Sequences

More...
RefSeqi
NP_766093.1, NM_172505.4
NP_941054.2, NM_198652.2
XP_006529783.1, XM_006529720.3

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
212427
381280

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:212427
mmu:381280

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB162219 mRNA Translation: BAD36742.1
AK042589 mRNA Translation: BAC31301.1
BC057309 mRNA Translation: AAH57309.1
BC131919 mRNA Translation: AAI31920.1
CCDSiCCDS15144.1 [Q6PG16-1]
RefSeqiNP_766093.1, NM_172505.4
NP_941054.2, NM_198652.2
XP_006529783.1, XM_006529720.3

3D structure databases

SMRiQ6PG16
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi237854, 3 interactors
STRINGi10090.ENSMUSP00000054263

PTM databases

iPTMnetiQ6PG16
PhosphoSitePlusiQ6PG16

Proteomic databases

jPOSTiQ6PG16
PaxDbiQ6PG16
PRIDEiQ6PG16
ProteomicsDBi273143 [Q6PG16-1]
273144 [Q6PG16-2]
273145 [Q6PG16-3]

Genome annotation databases

GeneIDi212427
381280
KEGGimmu:212427
mmu:381280

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
55355
MGIiMGI:2685821, Hjurp

Phylogenomic databases

eggNOGiENOG502SJZT, Eukaryota
InParanoidiQ6PG16
OrthoDBi426984at2759
PhylomeDBiQ6PG16

Enzyme and pathway databases

ReactomeiR-MMU-606279, Deposition of new CENPA-containing nucleosomes at the centromere

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
212427, 4 hits in 7 CRISPR screens
381280, 19 hits in 50 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Hjurp, mouse

Protein Ontology

More...
PROi
PR:Q6PG16
RNActiQ6PG16, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Family and domain databases

InterProiView protein in InterPro
IPR021052, HJURP
IPR022102, HJURP_C
IPR018465, Scm3/HJURP
PfamiView protein in Pfam
PF12347, HJURP_C, 2 hits
PF12346, HJURP_mid, 1 hit
PF10384, Scm3, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiHJURP_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6PG16
Secondary accession number(s): Q6BCZ4, Q8C9A7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 16, 2009
Last sequence update: July 5, 2004
Last modified: April 7, 2021
This is version 98 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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