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Entry version 139 (02 Jun 2021)
Sequence version 2 (27 Jul 2011)
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Protein

Tripartite motif-containing protein 45

Gene

Trim45

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May act as a transcriptional repressor in mitogen-activated protein kinase signaling pathway.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi135Zinc 1PROSITE-ProRule annotation1
Metal bindingi138Zinc 1PROSITE-ProRule annotation1
Metal bindingi158Zinc 1PROSITE-ProRule annotation1
Metal bindingi162Zinc 1PROSITE-ProRule annotation1
Metal bindingi191Zinc 2PROSITE-ProRule annotation1
Metal bindingi194Zinc 2PROSITE-ProRule annotation1
Metal bindingi214Zinc 2PROSITE-ProRule annotation1
Metal bindingi219Zinc 2PROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri29 – 98RING-typePROSITE-ProRule annotationAdd BLAST70
Zinc fingeri130 – 176B box-type 1PROSITE-ProRule annotationAdd BLAST47
Zinc fingeri186 – 227B box-type 2PROSITE-ProRule annotationAdd BLAST42

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Tripartite motif-containing protein 45
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Trim45
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1918187, Trim45

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000562671 – 580Tripartite motif-containing protein 45Add BLAST580

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q6PFY8

PRoteomics IDEntifications database

More...
PRIDEi
Q6PFY8

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
298219 [Q6PFY8-1]
298220 [Q6PFY8-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q6PFY8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q6PFY8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000033233, Expressed in utricle of membranous labyrinth and 211 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q6PFY8, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000043389

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q6PFY8, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q6PFY8

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati394 – 497FilaminAdd BLAST104

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili249 – 329Sequence analysisAdd BLAST81

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TRIM/RBCC family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri29 – 98RING-typePROSITE-ProRule annotationAdd BLAST70
Zinc fingeri130 – 176B box-type 1PROSITE-ProRule annotationAdd BLAST47
Zinc fingeri186 – 227B box-type 2PROSITE-ProRule annotationAdd BLAST42

Keywords - Domaini

Coiled coil, Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2177, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154334

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_013137_14_8_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q6PFY8

Identification of Orthologs from Complete Genome Data

More...
OMAi
SCCGKFA

Database of Orthologous Groups

More...
OrthoDBi
489543at2759

TreeFam database of animal gene trees

More...
TreeFami
TF324196

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003649, Bbox_C
IPR017868, Filamin/ABP280_repeat-like
IPR001298, Filamin/ABP280_rpt
IPR013783, Ig-like_fold
IPR014756, Ig_E-set
IPR027370, Znf-RING_LisH
IPR000315, Znf_B-box
IPR001841, Znf_RING
IPR017907, Znf_RING_CS

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00630, Filamin, 1 hit
PF00643, zf-B_box, 1 hit
PF13445, zf-RING_UBOX, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00502, BBC, 1 hit
SM00336, BBOX, 2 hits
SM00557, IG_FLMN, 1 hit
SM00184, RING, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF81296, SSF81296, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50194, FILAMIN_REPEAT, 1 hit
PS50119, ZF_BBOX, 2 hits
PS00518, ZF_RING_1, 1 hit
PS50089, ZF_RING_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q6PFY8-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSEIRKPLLG FVHKLQDANA SGSSGKTHCP TCLRLFKVPR LLPCLHTVCT
60 70 80 90 100
TCLEKLDPFS VVDIRGGDSD TSSEGSVFQD PELCSLQPQI GILCPVCDAQ
110 120 130 140 150
VDLPLGGVKA LTVDHLAMND VLLENLRGEG QGLVCDLCSD REVEKRCQTC
160 170 180 190 200
KANLCHFCCQ AHRRQKKTTY HTMVDLKDLK GYSQVGKPIL CPSHPAEELR
210 220 230 240 250
LFCELCDRPV CRDCVVGEHR EHPYDFTSNV IHKHGDSVRE LLRDTQPHVE
260 270 280 290 300
ALEDALAQIK SVNNALQERV EAVAADVRTF SEGYIKAIEE HRDKLLQQLD
310 320 330 340 350
DIRIQRETAL QLQKAQLEQL LADMRTGVEF TEHLLTSGSD LEILITKGVV
360 370 380 390 400
VERLRKLNKV EYSARPGVNH KICFSPQEKA GQCQGYEVYG AINTQEVDPA
410 420 430 440 450
QCVLQGEDLH RAREKQTASF TLFCKDASGQ SMGRGGDNVH VEVVPKDKKD
460 470 480 490 500
SPIRTVVQDN KDGSYRVSYT PKEPGIYTVW VCIREQHVQG SPFNVTVRRK
510 520 530 540 550
HRPHPGVFHC CTFCSSGGQK AARCACGGTM PGGYLGCGHG HKGHPGRPHW
560 570 580
SCCGKFIEKS ECSFTSGQGA PRSLLRTVAL
Length:580
Mass (Da):64,257
Last modified:July 27, 2011 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE08709D87D640247
GO
Isoform 2 (identifier: Q6PFY8-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     532-580: GGYLGCGHGH...PRSLLRTVAL → ARRPKQQQAR...MMIITVLPSR

Show »
Length:757
Mass (Da):83,936
Checksum:iD374255E7AB632D9
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A2ACL2A2ACL2_MOUSE
Tripartite motif-containing protein...
Trim45
531Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti250E → G in AAH57358 (PubMed:15489334).Curated1
Sequence conflicti303R → L in BAC36409 (PubMed:16141072).Curated1
Isoform 2 (identifier: Q6PFY8-2)
Sequence conflicti534R → S in BAC36409 (PubMed:16141072).Curated1
Sequence conflicti535P → T in BAC36409 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_012001532 – 580GGYLG…RTVAL → ARRPKQQQARVRPFAASQVD TLAVATDTKATRAVHTGLAV GSSLRSPSARSRVGRAPRGV CLGPWRSDASWGQVGPGNPE ASITSAMQRTQSLSSSKETD RIKDEVLSLTSDFKCFLCGH LSCTMAECRPPLHRSSRQAA DLLHGKLSCFIRALRCLCHG TMSSWSREDFMPSFPLCCSL SGLPRARVSGLLLEDETPLA HHLFVVYFQWFPSTQFMMII TVLPSR in isoform 2. CuratedAdd BLAST49

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK150574 mRNA Translation: BAE29669.1
AK153571 mRNA Translation: BAE32104.1
AK076600 mRNA Translation: BAC36409.1
AL669872 Genomic DNA No translation available.
BC057358 mRNA Translation: AAH57358.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS17678.1 [Q6PFY8-1]
CCDS51018.1 [Q6PFY8-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001159424.1, NM_001165952.1 [Q6PFY8-1]
NP_001159425.1, NM_001165953.1 [Q6PFY8-2]
NP_919324.2, NM_194343.2 [Q6PFY8-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000037409; ENSMUSP00000043389; ENSMUSG00000033233 [Q6PFY8-1]
ENSMUST00000106980; ENSMUSP00000102593; ENSMUSG00000033233 [Q6PFY8-1]
ENSMUST00000134993; ENSMUSP00000115669; ENSMUSG00000033233 [Q6PFY8-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
229644

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:229644

UCSC genome browser

More...
UCSCi
uc008qqy.2, mouse [Q6PFY8-1]
uc008qqz.2, mouse [Q6PFY8-2]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK150574 mRNA Translation: BAE29669.1
AK153571 mRNA Translation: BAE32104.1
AK076600 mRNA Translation: BAC36409.1
AL669872 Genomic DNA No translation available.
BC057358 mRNA Translation: AAH57358.1
CCDSiCCDS17678.1 [Q6PFY8-1]
CCDS51018.1 [Q6PFY8-2]
RefSeqiNP_001159424.1, NM_001165952.1 [Q6PFY8-1]
NP_001159425.1, NM_001165953.1 [Q6PFY8-2]
NP_919324.2, NM_194343.2 [Q6PFY8-1]

3D structure databases

SMRiQ6PFY8
ModBaseiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000043389

PTM databases

iPTMnetiQ6PFY8
PhosphoSitePlusiQ6PFY8

Proteomic databases

PaxDbiQ6PFY8
PRIDEiQ6PFY8
ProteomicsDBi298219 [Q6PFY8-1]
298220 [Q6PFY8-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
33887, 224 antibodies

The DNASU plasmid repository

More...
DNASUi
229644

Genome annotation databases

EnsembliENSMUST00000037409; ENSMUSP00000043389; ENSMUSG00000033233 [Q6PFY8-1]
ENSMUST00000106980; ENSMUSP00000102593; ENSMUSG00000033233 [Q6PFY8-1]
ENSMUST00000134993; ENSMUSP00000115669; ENSMUSG00000033233 [Q6PFY8-2]
GeneIDi229644
KEGGimmu:229644
UCSCiuc008qqy.2, mouse [Q6PFY8-1]
uc008qqz.2, mouse [Q6PFY8-2]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
80263
MGIiMGI:1918187, Trim45

Phylogenomic databases

eggNOGiKOG2177, Eukaryota
GeneTreeiENSGT00940000154334
HOGENOMiCLU_013137_14_8_1
InParanoidiQ6PFY8
OMAiSCCGKFA
OrthoDBi489543at2759
TreeFamiTF324196

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
229644, 0 hits in 53 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Ptgfrn, mouse

Protein Ontology

More...
PROi
PR:Q6PFY8
RNActiQ6PFY8, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000033233, Expressed in utricle of membranous labyrinth and 211 other tissues
GenevisibleiQ6PFY8, MM

Family and domain databases

Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR003649, Bbox_C
IPR017868, Filamin/ABP280_repeat-like
IPR001298, Filamin/ABP280_rpt
IPR013783, Ig-like_fold
IPR014756, Ig_E-set
IPR027370, Znf-RING_LisH
IPR000315, Znf_B-box
IPR001841, Znf_RING
IPR017907, Znf_RING_CS
PfamiView protein in Pfam
PF00630, Filamin, 1 hit
PF00643, zf-B_box, 1 hit
PF13445, zf-RING_UBOX, 1 hit
SMARTiView protein in SMART
SM00502, BBC, 1 hit
SM00336, BBOX, 2 hits
SM00557, IG_FLMN, 1 hit
SM00184, RING, 1 hit
SUPFAMiSSF81296, SSF81296, 1 hit
PROSITEiView protein in PROSITE
PS50194, FILAMIN_REPEAT, 1 hit
PS50119, ZF_BBOX, 2 hits
PS00518, ZF_RING_1, 1 hit
PS50089, ZF_RING_2, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTRI45_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6PFY8
Secondary accession number(s): E9Q2K9, Q3U5H4, Q8BVT5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 23, 2004
Last sequence update: July 27, 2011
Last modified: June 2, 2021
This is version 139 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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