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Entry version 157 (10 Feb 2021)
Sequence version 2 (17 Oct 2006)
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Protein

Zinc finger protein 613

Gene

ZNF613

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri204 – 226C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri232 – 254C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri260 – 282C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri288 – 310C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri316 – 338C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri344 – 366C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri372 – 394C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri400 – 422C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri428 – 450C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri456 – 478C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri484 – 506C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri512 – 535C2H2-type 12PROSITE-ProRule annotationAdd BLAST24

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q6PF04

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-212436, Generic Transcription Pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 613
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF613
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:25827, ZNF613

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q6PF04

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000176024.16

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
79898

Open Targets

More...
OpenTargetsi
ENSG00000176024

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134937067

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q6PF04, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZNF613

Domain mapping of disease mutations (DMDM)

More...
DMDMi
116242862

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002345971 – 617Zinc finger protein 613Add BLAST617

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q6PF04

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q6PF04

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q6PF04

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q6PF04

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q6PF04

PeptideAtlas

More...
PeptideAtlasi
Q6PF04

PRoteomics IDEntifications database

More...
PRIDEi
Q6PF04

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
67093 [Q6PF04-1]
67094 [Q6PF04-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q6PF04

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q6PF04

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000176024, Expressed in prostate gland and 119 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q6PF04, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q6PF04, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000176024, Tissue enhanced (prostate)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
122982, 5 interactors

Protein interaction database and analysis system

More...
IntActi
Q6PF04, 5 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000293471

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q6PF04, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q6PF04

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini8 – 78KRABPROSITE-ProRule annotationAdd BLAST71

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri204 – 226C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri232 – 254C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri260 – 282C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri288 – 310C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri316 – 338C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri344 – 366C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri372 – 394C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri400 – 422C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri428 – 450C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri456 – 478C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri484 – 506C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri512 – 535C2H2-type 12PROSITE-ProRule annotationAdd BLAST24

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
KOG1721, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000162851

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_002678_44_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q6PF04

Identification of Orthologs from Complete Genome Data

More...
OMAi
IKHQRTQ

Database of Orthologous Groups

More...
OrthoDBi
1318335at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q6PF04

TreeFam database of animal gene trees

More...
TreeFami
TF350804

Family and domain databases

Conserved Domains Database

More...
CDDi
cd07765, KRAB_A-box, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001909, KRAB
IPR036051, KRAB_dom_sf
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01352, KRAB, 1 hit
PF00096, zf-C2H2, 10 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00349, KRAB, 1 hit
SM00355, ZnF_C2H2, 12 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF109640, SSF109640, 1 hit
SSF57667, SSF57667, 7 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50805, KRAB, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 12 hits
PS50157, ZINC_FINGER_C2H2_2, 12 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q6PF04-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MIKSQESLTL EDVAVEFTWE EWQLLGPAQK DLYRDVMLEN YSNLVSVGYQ
60 70 80 90 100
ASKPDALFKL EQGEPWTVEN EIHSQICPEI KKVDNHLQMH SQKQRCLKRV
110 120 130 140 150
EQCHKHNAFG NIIHQRKSDF PLRQNHDTFD LHGKILKSNL SLVNQNKRYE
160 170 180 190 200
IKNSVGVNGD GKSFLHAKHE QFHNEMNFPE GGNSVNTNSQ FIKHQRTQNI
210 220 230 240 250
DKPHVCTECG KAFLKKSRLI YHQRVHTGEK PHGCSICGKA FSRKSGLTEH
260 270 280 290 300
QRNHTGEKPY ECTECDKAFR WKSQLNAHQK IHTGEKSYIC SDCGKGFIKK
310 320 330 340 350
SRLINHQRVH TGEKPHGCSL CGKAFSKRSR LTEHQRTHTG EKPYECTECD
360 370 380 390 400
KAFRWKSQLN AHQKAHTGEK SYICRDCGKG FIQKGNLIVH QRIHTGEKPY
410 420 430 440 450
ICNECGKGFI QKGNLLIHRR THTGEKPYVC NECGKGFSQK TCLISHQRFH
460 470 480 490 500
TGKTPFVCTE CGKSCSHKSG LINHQRIHTG EKPYTCSDCG KAFRDKSCLN
510 520 530 540 550
RHRRTHTGER PYGCSDCGKA FSHLSCLVYH KGMLHAREKC VGSVKLENPC
560 570 580 590 600
SESHSLSHTR DLIQDKDSVN MVTLQMPSVA AQTSLTNSAF QAESKVAIVS
610
QPVARSSVSA DSRICTE
Length:617
Mass (Da):70,143
Last modified:October 17, 2006 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i44C6B14BB2060322
GO
Isoform 2 (identifier: Q6PF04-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-36: Missing.

Show »
Length:581
Mass (Da):65,893
Checksum:iEAB48B2340469FF7
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
M0QX19M0QX19_HUMAN
Zinc finger protein 613
ZNF613
94Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M0R2C1M0R2C1_HUMAN
Zinc finger protein 613
ZNF613
85Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1B0GUH8A0A1B0GUH8_HUMAN
Zinc finger protein 613
ZNF613
237Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_02809684D → N1 PublicationCorresponds to variant dbSNP:rs17854933Ensembl.1
Natural variantiVAR_02809793K → E. Corresponds to variant dbSNP:rs8106409Ensembl.1
Natural variantiVAR_028098135I → R. Corresponds to variant dbSNP:rs16983243Ensembl.1
Natural variantiVAR_057428163S → F. Corresponds to variant dbSNP:rs33998555Ensembl.1
Natural variantiVAR_057429611D → V. Corresponds to variant dbSNP:rs16983253Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0183881 – 36Missing in isoform 2. 1 PublicationAdd BLAST36

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK027565 mRNA Translation: BAB55201.1
BC057776 mRNA Translation: AAH57776.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS12844.1 [Q6PF04-2]
CCDS33089.1 [Q6PF04-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001026891.2, NM_001031721.3 [Q6PF04-1]
NP_079116.2, NM_024840.3 [Q6PF04-2]
XP_005259326.1, XM_005259269.3 [Q6PF04-1]
XP_011525635.1, XM_011527333.2 [Q6PF04-1]
XP_016882804.1, XM_017027315.1 [Q6PF04-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000293471; ENSP00000293471; ENSG00000176024 [Q6PF04-1]
ENST00000391794; ENSP00000375671; ENSG00000176024 [Q6PF04-2]

Database of genes from NCBI RefSeq genomes

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GeneIDi
79898

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:79898

UCSC genome browser

More...
UCSCi
uc002pxz.3, human [Q6PF04-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK027565 mRNA Translation: BAB55201.1
BC057776 mRNA Translation: AAH57776.1
CCDSiCCDS12844.1 [Q6PF04-2]
CCDS33089.1 [Q6PF04-1]
RefSeqiNP_001026891.2, NM_001031721.3 [Q6PF04-1]
NP_079116.2, NM_024840.3 [Q6PF04-2]
XP_005259326.1, XM_005259269.3 [Q6PF04-1]
XP_011525635.1, XM_011527333.2 [Q6PF04-1]
XP_016882804.1, XM_017027315.1 [Q6PF04-2]

3D structure databases

SMRiQ6PF04
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi122982, 5 interactors
IntActiQ6PF04, 5 interactors
STRINGi9606.ENSP00000293471

PTM databases

iPTMnetiQ6PF04
PhosphoSitePlusiQ6PF04

Genetic variation databases

BioMutaiZNF613
DMDMi116242862

Proteomic databases

EPDiQ6PF04
jPOSTiQ6PF04
MassIVEiQ6PF04
MaxQBiQ6PF04
PaxDbiQ6PF04
PeptideAtlasiQ6PF04
PRIDEiQ6PF04
ProteomicsDBi67093 [Q6PF04-1]
67094 [Q6PF04-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
19057, 97 antibodies

Genome annotation databases

EnsembliENST00000293471; ENSP00000293471; ENSG00000176024 [Q6PF04-1]
ENST00000391794; ENSP00000375671; ENSG00000176024 [Q6PF04-2]
GeneIDi79898
KEGGihsa:79898
UCSCiuc002pxz.3, human [Q6PF04-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
79898
DisGeNETi79898

GeneCards: human genes, protein and diseases

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GeneCardsi
ZNF613
HGNCiHGNC:25827, ZNF613
HPAiENSG00000176024, Tissue enhanced (prostate)
neXtProtiNX_Q6PF04
OpenTargetsiENSG00000176024
PharmGKBiPA134937067
VEuPathDBiHostDB:ENSG00000176024.16

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG1721, Eukaryota
GeneTreeiENSGT00940000162851
HOGENOMiCLU_002678_44_0_1
InParanoidiQ6PF04
OMAiIKHQRTQ
OrthoDBi1318335at2759
PhylomeDBiQ6PF04
TreeFamiTF350804

Enzyme and pathway databases

PathwayCommonsiQ6PF04
ReactomeiR-HSA-212436, Generic Transcription Pathway

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
79898, 5 hits in 898 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
ZNF613, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
79898
PharosiQ6PF04, Tdark

Protein Ontology

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PROi
PR:Q6PF04
RNActiQ6PF04, protein

Gene expression databases

BgeeiENSG00000176024, Expressed in prostate gland and 119 other tissues
ExpressionAtlasiQ6PF04, baseline and differential
GenevisibleiQ6PF04, HS

Family and domain databases

CDDicd07765, KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909, KRAB
IPR036051, KRAB_dom_sf
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF01352, KRAB, 1 hit
PF00096, zf-C2H2, 10 hits
SMARTiView protein in SMART
SM00349, KRAB, 1 hit
SM00355, ZnF_C2H2, 12 hits
SUPFAMiSSF109640, SSF109640, 1 hit
SSF57667, SSF57667, 7 hits
PROSITEiView protein in PROSITE
PS50805, KRAB, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 12 hits
PS50157, ZINC_FINGER_C2H2_2, 12 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN613_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6PF04
Secondary accession number(s): Q96SS9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 16, 2006
Last sequence update: October 17, 2006
Last modified: February 10, 2021
This is version 157 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. SIMILARITY comments
    Index of protein domains and families
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