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Entry version 111 (07 Oct 2020)
Sequence version 1 (05 Jul 2004)
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Protein

Keratin-associated protein 26-1

Gene

KRTAP26-1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q6PEX3

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-6805567, Keratinization

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Keratin-associated protein 26-1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:KRTAP26-1
Synonyms:KAP26.1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 21

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000197683.4

Human Gene Nomenclature Database

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HGNCi
HGNC:33760, KRTAP26-1

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q6PEX3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Keratin

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162393763

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q6PEX3, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
KRTAP26-1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74737618

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002239161 – 210Keratin-associated protein 26-1Add BLAST210

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q6PEX3

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q6PEX3

PeptideAtlas

More...
PeptideAtlasi
Q6PEX3

PRoteomics IDEntifications database

More...
PRIDEi
Q6PEX3

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
67085

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Localized high up in the well differentiated portion of the hair follicle cuticle (about 10-15 cell layers above the apex of the dermal papilla).1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000197683, Expressed in placenta and 14 other tissues

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000197683, Group enriched (placenta, skin)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with hair keratins.

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Q6PEX3
With#Exp.IntAct
ACY3 [Q96HD9]3EBI-3957672,EBI-3916242
ARID5A [Q03989]3EBI-3957672,EBI-948603
C19orf54 - isoform 3 [Q5BKX5-3]3EBI-3957672,EBI-11976299
CARD10 [Q9BWT7]3EBI-3957672,EBI-3866279
CCNJL [F6RF56]3EBI-3957672,EBI-10177725
CELF5 [Q8N6W0]3EBI-3957672,EBI-12139335
CERCAM [Q5T4B2]3EBI-3957672,EBI-12261896
CFAP206 [Q8IYR0]3EBI-3957672,EBI-749051
COL8A1 [P27658]4EBI-3957672,EBI-747133
CYSRT1 [A8MQ03]3EBI-3957672,EBI-3867333
DAZAP2 [Q15038]3EBI-3957672,EBI-724310
DTX2 [Q86UW9]3EBI-3957672,EBI-740376
EFEMP2 [O95967]3EBI-3957672,EBI-743414
FAM168B - isoform 2 [A1KXE4-2]3EBI-3957672,EBI-12193763
FAM222B [Q8WU58]3EBI-3957672,EBI-2807642
GDPD5 [Q9HBR3]3EBI-3957672,EBI-10310206
GRN [P28799]8EBI-3957672,EBI-747754
HGS [A0A0S2Z4Q4]3EBI-3957672,EBI-16429135
HGS [O14964]3EBI-3957672,EBI-740220
HNF1B [P35680]3EBI-3957672,EBI-2798841
HOXA1 [P49639]8EBI-3957672,EBI-740785
ID3 [Q02535]3EBI-3957672,EBI-1387094
INTS11 [Q5TA45]3EBI-3957672,EBI-748258
KRT34 [O76011]3EBI-3957672,EBI-1047093
KRTAP1-1 [Q07627]3EBI-3957672,EBI-11959885
KRTAP10-5 [P60370]3EBI-3957672,EBI-10172150
KRTAP10-7 [P60409]3EBI-3957672,EBI-10172290
KRTAP10-9 [P60411]3EBI-3957672,EBI-10172052
KRTAP11-1 [Q8IUC1]3EBI-3957672,EBI-1052037
KRTAP12-1 [P59990]3EBI-3957672,EBI-10210845
KRTAP12-2 [P59991]6EBI-3957672,EBI-10176379
KRTAP13-2 [Q52LG2]3EBI-3957672,EBI-11953846
KRTAP19-6 [Q3LI70]3EBI-3957672,EBI-12805508
KRTAP19-7 [Q3SYF9]3EBI-3957672,EBI-10241353
KRTAP21-2 [Q3LI59]3EBI-3957672,EBI-18395721
KRTAP3-1 [Q9BYR8]3EBI-3957672,EBI-9996449
KRTAP3-2 [Q9BYR7]3EBI-3957672,EBI-751260
KRTAP4-12 [Q9BQ66]3EBI-3957672,EBI-739863
KRTAP4-2 [Q9BYR5]6EBI-3957672,EBI-10172511
KRTAP4-4 [Q9BYR3]3EBI-3957672,EBI-11958132
KRTAP4-7 [Q9BYR0]3EBI-3957672,EBI-10302547
KRTAP5-6 [Q6L8G9]6EBI-3957672,EBI-10250562
KRTAP6-1 [Q3LI64]3EBI-3957672,EBI-12111050
KRTAP6-2 [Q3LI66]6EBI-3957672,EBI-11962084
KRTAP8-1 [Q8IUC2]3EBI-3957672,EBI-10261141
KRTAP9-2 [Q9BYQ4]6EBI-3957672,EBI-1044640
KRTAP9-8 [Q9BYQ0]3EBI-3957672,EBI-11958364
LASP1 - isoform 2 [Q14847-2]3EBI-3957672,EBI-9088686
LCE2B [O14633]3EBI-3957672,EBI-11478468
MAPKBP1 [O60336]3EBI-3957672,EBI-947402
NHLRC4 [P0CG21]3EBI-3957672,EBI-12868744
NOTCH2NLA [Q7Z3S9]3EBI-3957672,EBI-945833
NOTCH2NLC [P0DPK4]3EBI-3957672,EBI-22310682
OTX1 [P32242]3EBI-3957672,EBI-740446
PITX1 [P78337]3EBI-3957672,EBI-748265
PLA2G10 [O15496]3EBI-3957672,EBI-726466
PM20D2 [Q8IYS1]3EBI-3957672,EBI-11339910
PRR35 [P0CG20]3EBI-3957672,EBI-11986293
PSMA3 [P25788]3EBI-3957672,EBI-348380
RASD1 [Q9Y272]3EBI-3957672,EBI-740818
RBPMS - isoform C [Q93062-3]3EBI-3957672,EBI-740343
RECK [Q6P9E2]3EBI-3957672,EBI-10253121
RHOXF2 [Q9BQY4]3EBI-3957672,EBI-372094
RNF208 [Q9H0X6]3EBI-3957672,EBI-751555
SF1 [Q15637]3EBI-3957672,EBI-744603
SIVA1 - isoform 2 [O15304-2]3EBI-3957672,EBI-12372219
SLC15A2 [Q16348]3EBI-3957672,EBI-12806032
SMARCC1 [Q92922]3EBI-3957672,EBI-355653
SMUG1 - isoform 2 [Q53HV7-2]3EBI-3957672,EBI-12275818
SPAG8 - isoform 2 [Q99932-2]3EBI-3957672,EBI-11959123
SPATA12 [Q7Z6I5]3EBI-3957672,EBI-10696971
STK16 [O75716]3EBI-3957672,EBI-749295
TEKT3 [Q9BXF9]3EBI-3957672,EBI-8644516
TEKT4 [Q8WW24]3EBI-3957672,EBI-750487
TEX37 [Q96LM6]3EBI-3957672,EBI-743976
TFAP2D [Q7Z6R9]3EBI-3957672,EBI-11952651
TFG [Q92734]3EBI-3957672,EBI-357061
TOX [O94900]3EBI-3957672,EBI-9088321
TRIM42 [Q8IWZ5]3EBI-3957672,EBI-5235829
TRIP13 [Q15645]3EBI-3957672,EBI-358993
TRIP6 [Q15654]3EBI-3957672,EBI-742327
VASN [Q6EMK4]3EBI-3957672,EBI-10249550
VENTX [O95231]3EBI-3957672,EBI-10191303
YTHDF1 [Q9BYJ9]3EBI-3957672,EBI-1051237
Hoxa1 [P09022] from Mus musculus.4EBI-3957672,EBI-3957603
tax [P03410] from Human T-cell leukemia virus 2.3EBI-3957672,EBI-9676218

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
132867, 93 interactors

Protein interaction database and analysis system

More...
IntActi
Q6PEX3, 90 interactors

Molecular INTeraction database

More...
MINTi
Q6PEX3

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000353742

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q6PEX3, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the PMG family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502SVJ1, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00730000111511

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_1312603_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q6PEX3

Identification of Orthologs from Complete Genome Data

More...
OMAi
CLAYRPQ

Database of Orthologous Groups

More...
OrthoDBi
1411177at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q6PEX3

TreeFam database of animal gene trees

More...
TreeFami
TF337331

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR007951, KRTAP_PMG

The PANTHER Classification System

More...
PANTHERi
PTHR19051, PTHR19051, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05287, PMG, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q6PEX3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSCPNYCSGN SNSGSLRTSR HIPLTSIDLC PTSVSCGDVL YLPTSSQDHT
60 70 80 90 100
WVTDNCQETC GEPTSCQPVH CETGNLETSC GSSTAYYVPR PCQGSSFLPA
110 120 130 140 150
SFFSSSCLPV SCRPQRYVSS GCRPLRPLLN SYQPIGDCVP NAYRPQFCLS
160 170 180 190 200
KSCQPQNLLT SGCQPSSCLA YRPQSLHVVS SSLRPLGPLF SGCQPLTHVF
210
STCRPSCSGL
Length:210
Mass (Da):22,554
Last modified:July 5, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7E4610AAF1044D6C
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_05347726S → Y. Corresponds to variant dbSNP:rs3804007Ensembl.1
Natural variantiVAR_053478188P → T. Corresponds to variant dbSNP:rs12483584Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB096936 mRNA Translation: BAE46351.1
AM941740 mRNA Translation: CAQ03502.1
BC057825 mRNA Translation: AAH57825.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS13588.1

NCBI Reference Sequences

More...
RefSeqi
NP_981950.1, NM_203405.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000360542; ENSP00000353742; ENSG00000197683

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
388818

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:388818

UCSC genome browser

More...
UCSCi
uc002ynw.5, human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB096936 mRNA Translation: BAE46351.1
AM941740 mRNA Translation: CAQ03502.1
BC057825 mRNA Translation: AAH57825.1
CCDSiCCDS13588.1
RefSeqiNP_981950.1, NM_203405.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi132867, 93 interactors
IntActiQ6PEX3, 90 interactors
MINTiQ6PEX3
STRINGi9606.ENSP00000353742

Polymorphism and mutation databases

BioMutaiKRTAP26-1
DMDMi74737618

Proteomic databases

MassIVEiQ6PEX3
PaxDbiQ6PEX3
PeptideAtlasiQ6PEX3
PRIDEiQ6PEX3
ProteomicsDBi67085

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
76496, 28 antibodies

The DNASU plasmid repository

More...
DNASUi
388818

Genome annotation databases

EnsembliENST00000360542; ENSP00000353742; ENSG00000197683
GeneIDi388818
KEGGihsa:388818
UCSCiuc002ynw.5, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
388818
EuPathDBiHostDB:ENSG00000197683.4

GeneCards: human genes, protein and diseases

More...
GeneCardsi
KRTAP26-1
HGNCiHGNC:33760, KRTAP26-1
HPAiENSG00000197683, Group enriched (placenta, skin)
neXtProtiNX_Q6PEX3
PharmGKBiPA162393763

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG502SVJ1, Eukaryota
GeneTreeiENSGT00730000111511
HOGENOMiCLU_1312603_0_0_1
InParanoidiQ6PEX3
OMAiCLAYRPQ
OrthoDBi1411177at2759
PhylomeDBiQ6PEX3
TreeFamiTF337331

Enzyme and pathway databases

PathwayCommonsiQ6PEX3
ReactomeiR-HSA-6805567, Keratinization

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
388818, 2 hits in 864 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
388818
PharosiQ6PEX3, Tdark

Protein Ontology

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PROi
PR:Q6PEX3
RNActiQ6PEX3, protein

Gene expression databases

BgeeiENSG00000197683, Expressed in placenta and 14 other tissues

Family and domain databases

InterProiView protein in InterPro
IPR007951, KRTAP_PMG
PANTHERiPTHR19051, PTHR19051, 1 hit
PfamiView protein in Pfam
PF05287, PMG, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiKR261_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6PEX3
Secondary accession number(s): B0RZD3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 21, 2006
Last sequence update: July 5, 2004
Last modified: October 7, 2020
This is version 111 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 21
    Human chromosome 21: entries, gene names and cross-references to MIM
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. SIMILARITY comments
    Index of protein domains and families
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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