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Protein

60S ribosomal protein L10

Gene

Rpl10

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Component of the large ribosomal subunit. Plays a role in the formation of actively translating ribosomes. May play a role in the embryonic brain development.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDevelopmental protein, Ribonucleoprotein, Ribosomal protein
Biological processTranslation regulation

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L10Curated
Alternative name(s):
Ribosomal protein L10Imported
Gene namesi
Name:Rpl10Imported
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome X

Organism-specific databases

RGDi621178 Rpl10

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved1 Publication
ChainiPRO_00001471102 – 21460S ribosomal protein L10Add BLAST213

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei32CitrullineBy similarity1
Cross-linki175Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki188Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)By similarity

Post-translational modificationi

Citrullinated by PADI4.By similarity

Keywords - PTMi

Citrullination, Isopeptide bond, Ubl conjugation

Proteomic databases

PaxDbiQ6PDV7
PRIDEiQ6PDV7

PTM databases

iPTMnetiQ6PDV7
PhosphoSitePlusiQ6PDV7

Expressioni

Gene expression databases

BgeeiENSRNOG00000056765
GenevisibleiQ6PDV7 RN

Interactioni

Subunit structurei

Component of the large ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S).By similarity

Protein-protein interaction databases

IntActiQ6PDV7, 1 interactor
STRINGi10116.ENSRNOP00000053123

Structurei

3D structure databases

ProteinModelPortaliQ6PDV7
SMRiQ6PDV7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG0857 Eukaryota
COG0197 LUCA
GeneTreeiENSGT00390000003897
HOGENOMiHOG000223754
HOVERGENiHBG002287
InParanoidiQ6PDV7
KOiK02866
OMAiPYTRKEY
OrthoDBiEOG091G0H9M
PhylomeDBiQ6PDV7
TreeFamiTF300082

Family and domain databases

CDDicd01433 Ribosomal_L16_L10e, 1 hit
Gene3Di3.90.1170.10, 1 hit
InterProiView protein in InterPro
IPR001197 Ribosomal_L10e
IPR016180 Ribosomal_L10e/L16
IPR036920 Ribosomal_L10e/L16_sf
IPR018255 Ribosomal_L10e_CS
PANTHERiPTHR11726 PTHR11726, 1 hit
PfamiView protein in Pfam
PF00252 Ribosomal_L16, 1 hit
PIRSFiPIRSF005590 Ribosomal_L10, 1 hit
SUPFAMiSSF54686 SSF54686, 1 hit
TIGRFAMsiTIGR00279 uL16_euk_arch, 1 hit
PROSITEiView protein in PROSITE
PS01257 RIBOSOMAL_L10E, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q6PDV7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGRRPARCYR YCKNKPYPKS RFCRGVPDAK IRIFDLGRKK AKVDEFPLCG
60 70 80 90 100
HMVSDEYEQL SSEALEAARI CANKYMVKSC GKDGFHIRVR LHPFHVIRIN
110 120 130 140 150
KMLSCAGADR LQTGMRGAFG KPQGTVARVH IGQVIMSIRT KLQNKEHVIE
160 170 180 190 200
ALRRAKFKFP GRQKIHISKK WGFTKFNADE FEDMVAEKRL IPDGCGVKYI
210
PNRGPLDKWR ALHS
Length:214
Mass (Da):24,604
Last modified:January 23, 2007 - v3
Checksum:i0860CECC91DF74FE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X87106 mRNA Translation: CAA60587.1
BC058467 mRNA Translation: AAH58467.1
PIRiJC4911
RefSeqiNP_112362.1, NM_031100.1
UniGeneiRn.102157

Genome annotation databases

EnsembliENSRNOT00000083951; ENSRNOP00000070105; ENSRNOG00000056765
GeneIDi81764
KEGGirno:81764

Similar proteinsi

Entry informationi

Entry nameiRL10_RAT
AccessioniPrimary (citable) accession number: Q6PDV7
Secondary accession number(s): P45634
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2004
Last sequence update: January 23, 2007
Last modified: May 23, 2018
This is version 112 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

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