UniProtKB - Q6PD56 (Q6PD56_HUMAN)
Protein
Submitted name:
ITSN1 protein
Gene
ITSN1
Organism
Homo sapiens (Human)
Status
Functioni
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Calcium bindingi | 66 – 77 | PROSITE-ProRule annotationAdd BLAST | 12 | |
Calcium bindingi | 267 – 278 | PROSITE-ProRule annotationAdd BLAST | 12 |
GO - Molecular functioni
- calcium ion binding Source: InterPro
Keywordsi
Ligand | CalciumPROSITE-ProRule annotation, Metal-bindingARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: ITSN1 proteinImported |
Gene namesi | Name:ITSN1Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 21 – 100 | EHInterPro annotationAdd BLAST | 80 | |
Domaini | 53 – 88 | EF-handInterPro annotationAdd BLAST | 36 | |
Domaini | 221 – 310 | EHInterPro annotationAdd BLAST | 90 | |
Domaini | 254 – 289 | EF-handInterPro annotationAdd BLAST | 36 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 322 – 348 | DisorderedSequence analysisAdd BLAST | 27 | |
Regioni | 615 – 634 | DisorderedSequence analysisAdd BLAST | 20 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 355 – 509 | Sequence analysisAdd BLAST | 155 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 330 – 348 | PolyampholyteSequence analysisAdd BLAST | 19 |
Keywords - Domaini
Coiled coilSequence analysisFamily and domain databases
CDDi | cd00052, EH, 2 hits |
InterProi | View protein in InterPro IPR011992, EF-hand-dom_pair IPR018247, EF_Hand_1_Ca_BS IPR002048, EF_hand_dom IPR000261, EH_dom |
Pfami | View protein in Pfam PF12763, EF-hand_4, 2 hits |
SMARTi | View protein in SMART SM00054, EFh, 2 hits SM00027, EH, 2 hits |
SUPFAMi | SSF47473, SSF47473, 2 hits |
PROSITEi | View protein in PROSITE PS00018, EF_HAND_1, 2 hits PS50222, EF_HAND_2, 2 hits PS50031, EH, 2 hits |
i Sequence
Sequence statusi: Fragment.
Q6PD56-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAQFPTPFGG SLDIWAITVE ERAKHDQQFH SLKPISGFIT GDQARNFFFQ
60 70 80 90 100
SGLPQPVLAQ IWALADMNND GRMDQVEFSI AMKLIKLKLQ GYQLPSALPP
110 120 130 140 150
VMKQQPVAIS SAPAFGMGGI ASMPPLTAVA PVPMGSIPVV GMSPTLVSSV
160 170 180 190 200
PTAAVPPLAN GAPPVIQPLP AFAHPAATLP KSSSFSRSGP GSQLNTKLQK
210 220 230 240 250
AQSFDVASVP PVAEWAVPQS SRLKYRQLFN SHDKTMSGHL TGPQARTILM
260 270 280 290 300
QSSLPQAQLA SIWNLSDIDQ DGKLTAEEFI LAMHLIDVAM SGQPLPPVLP
310 320 330 340 350
PEYIPPSFRR VRSGSGISVI SSTSVDQRLP EEPVLEDEQQ QLEKKLPVTF
360 370 380 390 400
EDKKRENFER GNLELEKRRQ ALLEQQRKEQ ERLAQLERAE QERKERERQE
410 420 430 440 450
QERKRQLELE KQLEKQRELE RQREEERRKE IERREAAKRE LERQRQLEWE
460 470 480 490 500
RNRRQELLNQ RNKEQEDIVV LKAKKKTLEF ELEALNDKKH QLEGKLQDIR
510 520 530 540 550
CRLTTQRQEI ESTNKSRELR IAEITHLQQQ LQESQQMLGR LIPEKQILND
560 570 580 590 600
QLKQVQQNSL HRDSLVTLKR ALEAKELARQ HLRDQLDEVE KETRSKLQEI
610 620 630
DIFNNQLKEL REIHNKQQLQ KQKSMEAERL KKKK
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 634 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC058925 mRNA Translation: AAH58925.1 |
RefSeqi | NP_001001132.1, NM_001001132.1 NP_003015.2, NM_003024.2 |
Genome annotation databases
GeneIDi | 6453 |
KEGGi | hsa:6453 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC058925 mRNA Translation: AAH58925.1 |
RefSeqi | NP_001001132.1, NM_001001132.1 NP_003015.2, NM_003024.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | Q6PD56 |
Protocols and materials databases
DNASUi | 6453 |
Genome annotation databases
GeneIDi | 6453 |
KEGGi | hsa:6453 |
Organism-specific databases
CTDi | 6453 |
PharmGKBi | PA29981 |
Miscellaneous databases
BioGRID-ORCSi | 6453, 7 hits in 996 CRISPR screens |
ChiTaRSi | ITSN1, human |
GenomeRNAii | 6453 |
Gene expression databases
Genevisiblei | Q6PD56, HS |
Family and domain databases
CDDi | cd00052, EH, 2 hits |
InterProi | View protein in InterPro IPR011992, EF-hand-dom_pair IPR018247, EF_Hand_1_Ca_BS IPR002048, EF_hand_dom IPR000261, EH_dom |
Pfami | View protein in Pfam PF12763, EF-hand_4, 2 hits |
SMARTi | View protein in SMART SM00054, EFh, 2 hits SM00027, EH, 2 hits |
SUPFAMi | SSF47473, SSF47473, 2 hits |
PROSITEi | View protein in PROSITE PS00018, EF_HAND_1, 2 hits PS50222, EF_HAND_2, 2 hits PS50031, EH, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q6PD56_HUMAN | |
Accessioni | Q6PD56Primary (citable) accession number: Q6PD56 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 5, 2004 |
Last sequence update: | July 5, 2004 | |
Last modified: | April 7, 2021 | |
This is version 96 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |