UniProtKB - Q6PD05 (ZN821_MOUSE)
Protein
Zinc finger protein 821
Gene
Znf821
Organism
Mus musculus (Mouse)
Status
Functioni
May be involved in transcriptional regulation.
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 117 – 141 | C2H2-type 1PROSITE-ProRule annotationAdd BLAST | 25 | |
Zinc fingeri | 151 – 173 | C2H2-type 2PROSITE-ProRule annotationAdd BLAST | 23 |
GO - Molecular functioni
- DNA-binding transcription factor activity Source: GO_Central
- metal ion binding Source: UniProtKB-KW
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: GO_Central
- sequence-specific double-stranded DNA binding Source: MGI
GO - Biological processi
- regulation of transcription by RNA polymerase II Source: GO_Central
Keywordsi
Molecular function | DNA-binding |
Biological process | Transcription, Transcription regulation |
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Recommended name: Zinc finger protein 821 |
Gene namesi | Name:Znf821 Synonyms:Zfp821 |
Organismi | Mus musculus (Mouse) |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:1923121, Zfp821 |
Subcellular locationi
Nucleus
- Nucleus Curated
Nucleus
- nuclear chromatin Source: GO_Central
Keywords - Cellular componenti
NucleusPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000317290 | 1 – 413 | Zinc finger protein 821Add BLAST | 413 |
Proteomic databases
PaxDbi | Q6PD05 |
PRIDEi | Q6PD05 |
PTM databases
iPTMneti | Q6PD05 |
PhosphoSitePlusi | Q6PD05 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000031728, Expressed in cochlea and 239 other tissues |
ExpressionAtlasi | Q6PD05, baseline and differential |
Genevisiblei | Q6PD05, MM |
Interactioni
Protein-protein interaction databases
BioGRIDi | 217810, 1 interactor |
STRINGi | 10090.ENSMUSP00000034163 |
Miscellaneous databases
RNActi | Q6PD05, protein |
Family & Domainsi
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 260 – 367 | Sequence analysisAdd BLAST | 108 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 53 – 58 | Poly-Ser | 6 |
Sequence similaritiesi
Belongs to the krueppel C2H2-type zinc-finger protein family.Curated
Zinc finger
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 117 – 141 | C2H2-type 1PROSITE-ProRule annotationAdd BLAST | 25 | |
Zinc fingeri | 151 – 173 | C2H2-type 2PROSITE-ProRule annotationAdd BLAST | 23 |
Keywords - Domaini
Coiled coil, Repeat, Zinc-fingerPhylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000159421 |
HOGENOMi | CLU_048218_0_0_1 |
InParanoidi | Q6PD05 |
OrthoDBi | 901424at2759 |
TreeFami | TF326851 |
Family and domain databases
InterProi | View protein in InterPro IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
SMARTi | View protein in SMART SM00355, ZnF_C2H2, 2 hits |
SUPFAMi | SSF57667, SSF57667, 1 hit |
PROSITEi | View protein in PROSITE PS00028, ZINC_FINGER_C2H2_1, 2 hits PS50157, ZINC_FINGER_C2H2_2, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
Q6PD05-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSRRKQTNPN KVHWDQVFAG LEEQARQAMM KTDFPGDLGS QRQAIQQLRD
60 70 80 90 100
QDSSSSDSEG DEEETTQDEV SSHTSEEDGG VVKVEKELET AEAPVSSGDA
110 120 130 140 150
LAEREVTENL NSDPLLQLCQ CPLCQLDCGS REQLIAHVYQ HTAAVVSAKS
160 170 180 190 200
YMCPVCGRAL SSPGSLGRHL LIHSEDQRSN CAVCGARFTS HATFNSEKLP
210 220 230 240 250
QVLNMESVPQ VHSEGPSSAE GKDIACSPPV YPAGILLVCN NCAAYRKLLE
260 270 280 290 300
TQTPSVRKWA LRRQNEPLEV RLQRLERERT AKKSRRDNET PEEREVRRMR
310 320 330 340 350
DREAKRLQRM QETDEQRARR LQRDREAMRL KRANETPEKR QARLIREREA
360 370 380 390 400
KRLKRRLEKM DMMLRAQFGQ DPSAMAALAA EMNFFQLPVS GVELDSQLLG
410
KMAFEEQNNS SLH
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A1D5RLA9 | A0A1D5RLA9_MOUSE | Zinc finger protein 821 | Zfp821 | 404 | Annotation score: | ||
A0A1D5RLE5 | A0A1D5RLE5_MOUSE | Zinc finger protein 821 | Zfp821 | 262 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 215 | G → V in BAE22853 (PubMed:16141072).Curated | 1 | |
Sequence conflicti | 271 | R → T in AAH59014 (PubMed:15489334).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC132138 Genomic DNA No translation available. BC059014 mRNA Translation: AAH59014.1 AK136168 mRNA Translation: BAE22853.1 |
CCDSi | CCDS40473.1 |
RefSeqi | NP_001161418.1, NM_001167946.2 NP_001273322.1, NM_001286393.1 NP_083744.2, NM_029468.3 XP_011246835.1, XM_011248533.2 XP_011246836.1, XM_011248534.2 XP_011246837.1, XM_011248535.1 XP_011246838.1, XM_011248536.2 XP_017168486.1, XM_017312997.1 |
Genome annotation databases
Ensembli | ENSMUST00000034163; ENSMUSP00000034163; ENSMUSG00000031728 ENSMUST00000212000; ENSMUSP00000148348; ENSMUSG00000031728 |
GeneIDi | 75871 |
KEGGi | mmu:75871 |
UCSCi | uc009njb.1, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC132138 Genomic DNA No translation available. BC059014 mRNA Translation: AAH59014.1 AK136168 mRNA Translation: BAE22853.1 |
CCDSi | CCDS40473.1 |
RefSeqi | NP_001161418.1, NM_001167946.2 NP_001273322.1, NM_001286393.1 NP_083744.2, NM_029468.3 XP_011246835.1, XM_011248533.2 XP_011246836.1, XM_011248534.2 XP_011246837.1, XM_011248535.1 XP_011246838.1, XM_011248536.2 XP_017168486.1, XM_017312997.1 |
3D structure databases
SMRi | Q6PD05 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 217810, 1 interactor |
STRINGi | 10090.ENSMUSP00000034163 |
PTM databases
iPTMneti | Q6PD05 |
PhosphoSitePlusi | Q6PD05 |
Proteomic databases
PaxDbi | Q6PD05 |
PRIDEi | Q6PD05 |
Protocols and materials databases
Antibodypediai | 16662, 91 antibodies |
Genome annotation databases
Ensembli | ENSMUST00000034163; ENSMUSP00000034163; ENSMUSG00000031728 ENSMUST00000212000; ENSMUSP00000148348; ENSMUSG00000031728 |
GeneIDi | 75871 |
KEGGi | mmu:75871 |
UCSCi | uc009njb.1, mouse |
Organism-specific databases
CTDi | 75871 |
MGIi | MGI:1923121, Zfp821 |
Phylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000159421 |
HOGENOMi | CLU_048218_0_0_1 |
InParanoidi | Q6PD05 |
OrthoDBi | 901424at2759 |
TreeFami | TF326851 |
Miscellaneous databases
BioGRID-ORCSi | 75871, 1 hit in 17 CRISPR screens |
ChiTaRSi | Zfp821, mouse |
PROi | PR:Q6PD05 |
RNActi | Q6PD05, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000031728, Expressed in cochlea and 239 other tissues |
ExpressionAtlasi | Q6PD05, baseline and differential |
Genevisiblei | Q6PD05, MM |
Family and domain databases
InterProi | View protein in InterPro IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
SMARTi | View protein in SMART SM00355, ZnF_C2H2, 2 hits |
SUPFAMi | SSF57667, SSF57667, 1 hit |
PROSITEi | View protein in PROSITE PS00028, ZINC_FINGER_C2H2_1, 2 hits PS50157, ZINC_FINGER_C2H2_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | ZN821_MOUSE | |
Accessioni | Q6PD05Primary (citable) accession number: Q6PD05 Secondary accession number(s): E9Q0F1, Q3UWR1 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 5, 2008 |
Last sequence update: | July 27, 2011 | |
Last modified: | December 2, 2020 | |
This is version 130 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot - SIMILARITY comments
Index of protein domains and families