UniProtKB - Q6PC69 (RL10A_DANRE)
Protein
60S ribosomal protein L10a
Gene
rpl10a
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Functioni
Component of the large ribosomal subunit.By similarity
GO - Molecular functioni
- RNA binding Source: GO_Central
- structural constituent of ribosome Source: InterPro
GO - Biological processi
- maturation of LSU-rRNA Source: GO_Central
- translation Source: InterPro
Keywordsi
Molecular function | Ribonucleoprotein, Ribosomal protein |
Enzyme and pathway databases
Reactomei | R-DRE-156827, L13a-mediated translational silencing of Ceruloplasmin expression R-DRE-1799339, SRP-dependent cotranslational protein targeting to membrane R-DRE-6791226, Major pathway of rRNA processing in the nucleolus and cytosol R-DRE-72706, GTP hydrolysis and joining of the 60S ribosomal subunit R-DRE-975956, Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-DRE-975957, Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) |
Names & Taxonomyi
Protein namesi | Recommended name: 60S ribosomal protein L10a |
Gene namesi | Name:rpl10a ORF Names:zgc:73082 |
Organismi | Danio rerio (Zebrafish) (Brachydanio rerio) |
Taxonomic identifieri | 7955 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio |
Proteomesi |
|
Organism-specific databases
ZFINi | ZDB-GENE-030131-2025, rpl10a |
Subcellular locationi
Cytosol
- cytosolic large ribosomal subunit Source: GO_Central
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000125824 | 1 – 216 | 60S ribosomal protein L10aAdd BLAST | 216 |
Proteomic databases
PaxDbi | Q6PC69 |
PRIDEi | Q6PC69 |
Expressioni
Gene expression databases
Bgeei | ENSDARG00000042905, Expressed in pharyngeal gill and 33 other tissues |
ExpressionAtlasi | Q6PC69, baseline |
Interactioni
Subunit structurei
Component of the large ribosomal subunit.
By similarityProtein-protein interaction databases
STRINGi | 7955.ENSDARP00000062982 |
Family & Domainsi
Sequence similaritiesi
Belongs to the universal ribosomal protein uL1 family.Curated
Phylogenomic databases
eggNOGi | KOG1570, Eukaryota |
GeneTreei | ENSGT00390000008767 |
HOGENOMi | CLU_062853_3_0_1 |
InParanoidi | Q6PC69 |
OMAi | TMAINFL |
OrthoDBi | 1172076at2759 |
PhylomeDBi | Q6PC69 |
TreeFami | TF300791 |
Family and domain databases
CDDi | cd00403, Ribosomal_L1, 1 hit |
Gene3Di | 3.40.50.790, 1 hit |
InterProi | View protein in InterPro IPR002143, Ribosomal_L1 IPR023674, Ribosomal_L1-like IPR028364, Ribosomal_L1/biogenesis IPR016095, Ribosomal_L1_3-a/b-sand IPR023673, Ribosomal_L1_CS |
Pfami | View protein in Pfam PF00687, Ribosomal_L1, 1 hit |
PIRSFi | PIRSF002155, Ribosomal_L1, 1 hit |
SUPFAMi | SSF56808, SSF56808, 1 hit |
PROSITEi | View protein in PROSITE PS01199, RIBOSOMAL_L1, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
Q6PC69-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSKVSRDTLY EAVKEVQAGS RRKKRKFLET VELQISLKNY DPQKDKRFSG
60 70 80 90 100
TVRLKTTPRP KFSVCVLGDQ QHCDEAKAAE LPHMDIEALK KLNKNKKLVK
110 120 130 140 150
KLAKKYDAFL ASESLIKQIP RILGPGLNKA GKFPSLLTHN ENLGTKVDEV
160 170 180 190 200
KSTIKFQMKK VLCLAVAVGH VKMSEEELVY NIHLAVNFLV SLLKKNWQNV
210
RALYIKSTMG KPQRLY
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A2R8Q8M5 | A0A2R8Q8M5_DANRE | Ribosomal protein | rpl10a | 164 | Annotation score: | ||
E9QFD9 | E9QFD9_DANRE | 60S ribosomal protein L10a | rpl10a | 67 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 61 | K → Q in AAH71510 (Ref. 1) Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC059454 mRNA Translation: AAH59454.1 BC071510 mRNA Translation: AAH71510.1 |
RefSeqi | NP_955930.1, NM_199636.1 |
Genome annotation databases
Ensembli | ENSDART00000062983; ENSDARP00000062982; ENSDARG00000042905 |
GeneIDi | 323305 |
KEGGi | dre:323305 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC059454 mRNA Translation: AAH59454.1 BC071510 mRNA Translation: AAH71510.1 |
RefSeqi | NP_955930.1, NM_199636.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 7955.ENSDARP00000062982 |
Proteomic databases
PaxDbi | Q6PC69 |
PRIDEi | Q6PC69 |
Genome annotation databases
Ensembli | ENSDART00000062983; ENSDARP00000062982; ENSDARG00000042905 |
GeneIDi | 323305 |
KEGGi | dre:323305 |
Organism-specific databases
CTDi | 4736 |
ZFINi | ZDB-GENE-030131-2025, rpl10a |
Phylogenomic databases
eggNOGi | KOG1570, Eukaryota |
GeneTreei | ENSGT00390000008767 |
HOGENOMi | CLU_062853_3_0_1 |
InParanoidi | Q6PC69 |
OMAi | TMAINFL |
OrthoDBi | 1172076at2759 |
PhylomeDBi | Q6PC69 |
TreeFami | TF300791 |
Enzyme and pathway databases
Reactomei | R-DRE-156827, L13a-mediated translational silencing of Ceruloplasmin expression R-DRE-1799339, SRP-dependent cotranslational protein targeting to membrane R-DRE-6791226, Major pathway of rRNA processing in the nucleolus and cytosol R-DRE-72706, GTP hydrolysis and joining of the 60S ribosomal subunit R-DRE-975956, Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-DRE-975957, Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) |
Miscellaneous databases
PROi | PR:Q6PC69 |
Gene expression databases
Bgeei | ENSDARG00000042905, Expressed in pharyngeal gill and 33 other tissues |
ExpressionAtlasi | Q6PC69, baseline |
Family and domain databases
CDDi | cd00403, Ribosomal_L1, 1 hit |
Gene3Di | 3.40.50.790, 1 hit |
InterProi | View protein in InterPro IPR002143, Ribosomal_L1 IPR023674, Ribosomal_L1-like IPR028364, Ribosomal_L1/biogenesis IPR016095, Ribosomal_L1_3-a/b-sand IPR023673, Ribosomal_L1_CS |
Pfami | View protein in Pfam PF00687, Ribosomal_L1, 1 hit |
PIRSFi | PIRSF002155, Ribosomal_L1, 1 hit |
SUPFAMi | SSF56808, SSF56808, 1 hit |
PROSITEi | View protein in PROSITE PS01199, RIBOSOMAL_L1, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | RL10A_DANRE | |
Accessioni | Q6PC69Primary (citable) accession number: Q6PC69 Secondary accession number(s): Q6IQA0 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | August 31, 2004 |
Last sequence update: | July 5, 2004 | |
Last modified: | December 2, 2020 | |
This is version 94 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families - Ribosomal proteins
Ribosomal proteins families and list of entries