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Protein
Submitted name:

Lysosomal multispanning membrane protein 5

Gene

Laptm5

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Lysosomal multispanning membrane protein 5Imported
Submitted name:
Lysosomal protein transmembrane 5Imported
Submitted name:
Lysosomal-associated protein transmembrane 5Imported
Gene namesi
Name:Laptm5Imported
ORF Names:rCG_30789Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 5

Organism-specific databases

RGDi621838 Laptm5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei20 – 41HelicalSequence analysisAdd BLAST22
Transmembranei62 – 85HelicalSequence analysisAdd BLAST24
Transmembranei91 – 115HelicalSequence analysisAdd BLAST25
Transmembranei183 – 205HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSRNOG00000011054 Expressed in 10 organ(s), highest expression level in spleen

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000015198

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IFZA Eukaryota
ENOG410YPPU LUCA
GeneTreeiENSGT00390000012862
HOGENOMiHOG000113282
HOVERGENiHBG052307
KOiK12387
OMAiSQFIKMM
OrthoDBiEOG091G0JRF
TreeFamiTF330843

Family and domain databases

InterProiView protein in InterPro
IPR004687 LAPTM4/5
IPR018396 LAPTM_4A/5
IPR018397 Lysosomal-assoc_TM_prot5
PANTHERiPTHR12479:SF2 PTHR12479:SF2, 3 hits
PfamiView protein in Pfam
PF03821 Mtp, 1 hit
TIGRFAMsiTIGR00799 mtp, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q6P9Z7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASRAVPVRQ TCCCFNVRVA TVALAIYHIV MSVLLFIEHV VEVARGKVSC
60 70 80 90 100
RFSKMPYLRL ADLLSSFLLI GVLFIISLSL LFGVVKNREK YLIPFLSLQI
110 120 130 140 150
MDFLLCLLTL LGSYIELPAY LKFARPRPGP SKVPLMTLQL LDFCLSILTL
160 170 180 190 200
CSSYMEVPTY LNFKSMNHMN YLPSQEGMPR SQFINMMLIF SVAFITVLIL
210 220 230 240 250
KVYMFKCVWT CYRFMKHMNS AVEDSSSKLF LKVALPSYEE ALSLPTKTPE
260
GDLAPPPYSE V
Length:261
Mass (Da):29,648
Last modified:July 5, 2004 - v1
Checksum:i5743EABCBE214DDE
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0G2K184A0A0G2K184_RAT
Lysosomal protein transmembrane 5
Laptm5
257Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07050048 Genomic DNA No translation available.
BC060517 mRNA Translation: AAH60517.1
CH473968 Genomic DNA Translation: EDL80601.1
RefSeqiNP_445990.2, NM_053538.2
UniGeneiRn.24799

Genome annotation databases

EnsembliENSRNOT00000015198; ENSRNOP00000015198; ENSRNOG00000011054
GeneIDi89783
KEGGirno:89783

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07050048 Genomic DNA No translation available.
BC060517 mRNA Translation: AAH60517.1
CH473968 Genomic DNA Translation: EDL80601.1
RefSeqiNP_445990.2, NM_053538.2
UniGeneiRn.24799

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000015198

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000015198; ENSRNOP00000015198; ENSRNOG00000011054
GeneIDi89783
KEGGirno:89783

Organism-specific databases

CTDi7805
RGDi621838 Laptm5

Phylogenomic databases

eggNOGiENOG410IFZA Eukaryota
ENOG410YPPU LUCA
GeneTreeiENSGT00390000012862
HOGENOMiHOG000113282
HOVERGENiHBG052307
KOiK12387
OMAiSQFIKMM
OrthoDBiEOG091G0JRF
TreeFamiTF330843

Gene expression databases

BgeeiENSRNOG00000011054 Expressed in 10 organ(s), highest expression level in spleen

Family and domain databases

InterProiView protein in InterPro
IPR004687 LAPTM4/5
IPR018396 LAPTM_4A/5
IPR018397 Lysosomal-assoc_TM_prot5
PANTHERiPTHR12479:SF2 PTHR12479:SF2, 3 hits
PfamiView protein in Pfam
PF03821 Mtp, 1 hit
TIGRFAMsiTIGR00799 mtp, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ6P9Z7_RAT
AccessioniPrimary (citable) accession number: Q6P9Z7
Secondary accession number(s): F1LN25
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: November 7, 2018
This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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