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UniProtKB - Q6P9Y7 (ZFP82_MOUSE)
Protein
Zinc finger protein 82
Gene
Zfp82
Organism
Mus musculus (Mouse)
Status
Functioni
May be involved in transcriptional regulation.
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 168 – 190 | C2H2-type 1PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 196 – 218 | C2H2-type 2PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 224 – 246 | C2H2-type 3PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 252 – 274 | C2H2-type 4PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 280 – 302 | C2H2-type 5; degeneratePROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 308 – 330 | C2H2-type 6PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 336 – 358 | C2H2-type 7PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 364 – 386 | C2H2-type 8PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 392 – 414 | C2H2-type 9PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 420 – 442 | C2H2-type 10PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 448 – 470 | C2H2-type 11PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 476 – 498 | C2H2-type 12PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 504 – 526 | C2H2-type 13PROSITE-ProRule annotationAdd BLAST | 23 |
GO - Molecular functioni
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: GO_Central
- metal ion binding Source: UniProtKB-KW
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: GO_Central
GO - Biological processi
- regulation of transcription by RNA polymerase II Source: GO_Central
Keywordsi
Molecular function | DNA-binding |
Biological process | Transcription, Transcription regulation |
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Recommended name: Zinc finger protein 82Short name: Zfp-82 Alternative name(s): Zinc finger protein 545 |
Gene namesi | Name:Zfp82 Synonyms:Kiaa1948, Znf545 |
Organismi | Mus musculus (Mouse) |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:1890753, Zfp82 |
VEuPathDBi | HostDB:ENSMUSG00000098022 |
Subcellular locationi
Nucleus
- Nucleus Curated
Nucleus
- nucleus Source: GO_Central
Keywords - Cellular componenti
NucleusPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000233165 | 1 – 530 | Zinc finger protein 82Add BLAST | 530 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Cross-linki | 125 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity |
Keywords - PTMi
Isopeptide bond, Ubl conjugationProteomic databases
MaxQBi | Q6P9Y7 |
PaxDbi | Q6P9Y7 |
PRIDEi | Q6P9Y7 |
ProteomicsDBi | 274988 [Q6P9Y7-1] 274989 [Q6P9Y7-2] |
PTM databases
PhosphoSitePlusi | Q6P9Y7 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000098022, Expressed in testis and 77 other tissues |
Genevisiblei | Q6P9Y7, MM |
Interactioni
Protein-protein interaction databases
BioGRIDi | 236978, 2 interactors |
IntActi | Q6P9Y7, 2 interactors |
STRINGi | 10090.ENSMUSP00000079647 |
Miscellaneous databases
RNActi | Q6P9Y7, protein |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 6 – 77 | KRABPROSITE-ProRule annotationAdd BLAST | 72 |
Sequence similaritiesi
Belongs to the krueppel C2H2-type zinc-finger protein family.Curated
Zinc finger
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 168 – 190 | C2H2-type 1PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 196 – 218 | C2H2-type 2PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 224 – 246 | C2H2-type 3PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 252 – 274 | C2H2-type 4PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 280 – 302 | C2H2-type 5; degeneratePROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 308 – 330 | C2H2-type 6PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 336 – 358 | C2H2-type 7PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 364 – 386 | C2H2-type 8PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 392 – 414 | C2H2-type 9PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 420 – 442 | C2H2-type 10PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 448 – 470 | C2H2-type 11PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 476 – 498 | C2H2-type 12PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 504 – 526 | C2H2-type 13PROSITE-ProRule annotationAdd BLAST | 23 |
Keywords - Domaini
Repeat, Zinc-fingerPhylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000162531 |
HOGENOMi | CLU_002678_69_8_1 |
InParanoidi | Q6P9Y7 |
OMAi | QHQSIHV |
OrthoDBi | 1318335at2759 |
PhylomeDBi | Q6P9Y7 |
TreeFami | TF341817 |
Family and domain databases
CDDi | cd07765, KRAB_A-box, 1 hit |
InterProi | View protein in InterPro IPR001909, KRAB IPR036051, KRAB_dom_sf IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF01352, KRAB, 1 hit PF00096, zf-C2H2, 10 hits |
SMARTi | View protein in SMART SM00349, KRAB, 1 hit SM00355, ZnF_C2H2, 13 hits |
SUPFAMi | SSF109640, SSF109640, 1 hit SSF57667, SSF57667, 7 hits |
PROSITEi | View protein in PROSITE PS50805, KRAB, 1 hit PS00028, ZINC_FINGER_C2H2_1, 12 hits PS50157, ZINC_FINGER_C2H2_2, 13 hits |
s (3+)i Sequence
Sequence statusi: Complete.
This entry describes 3 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 3 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All
Isoform 1 (identifier: Q6P9Y7-1) [UniParc]FASTAAdd to basket
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MARVSVVFSD VSIAFSQEEW ESLDLEQRNL YKDVMMENYH NVASLGCFIS
60 70 80 90 100
KPDVISLLEQ GKEPWKVVRQ RKPCPDSETK DETNQVFSEN GIYEMNLSQW
110 120 130 140 150
KIMERIGNSG LKSLLLKNGW ESRRKQERQE DPQEGYLSQV RHTSERVSSY
160 170 180 190 200
EKRALTTRQR IHFVEKPYEC NECGKAFRVR QQLTFHHRIH TGEKPYECKE
210 220 230 240 250
CGMAFRQTAH LTRHQRLHSG EKLYECKECG QAFIYGPELR AHQKLHTGEK
260 270 280 290 300
PYTCRECGKA FRVRGQLTLH QRIHTGEKPY VCQECGKAFR QLAHLTRHQK
310 320 330 340 350
LNVVDRLYEC KECGKDFLCG SGLRVHHKLH TGEKPYECKD CGKAFRVRQQ
360 370 380 390 400
LTLHQRSHTG EKPYECTECG KTFSRGYHLI LHHRIHTGEK PYECKECWKA
410 420 430 440 450
FSRYSQLISH QSIHIGVKPY DCKDCGKAFR LLSQLTQHQS VHAGEKPYSC
460 470 480 490 500
KECGKSFRLR QKLALHQSIH TGEKPFECKE CRKAFRLNSS LIQHLRIHSG
510 520 530
EKPYECKECK KAFRQHSHLT HHLKVHTVKV
Computationally mapped potential isoform sequencesi
There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketS4R1G9 | S4R1G9_MOUSE | Zinc finger protein 82 | Zfp82 | 500 | Annotation score: | ||
S4R2K1 | S4R2K1_MOUSE | Zinc finger protein 82 | Zfp82 | 64 | Annotation score: | ||
S4R2H1 | S4R2H1_MOUSE | Zinc finger protein 82 | Zfp82 | 23 | Annotation score: |
Sequence cautioni
The sequence BAC29755 differs from that shown. Reason: Erroneous translation. Wrong choice of CDS.Curated
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_018083 | 68 – 76 | VRQRKPCPD → TMGDPGRTN in isoform 2. 1 Publication | 9 | |
Alternative sequenceiVSP_046230 | 76 – 83 | DSETKDET → ARRDGASL in isoform 3. 1 Publication | 8 | |
Alternative sequenceiVSP_046231 | 84 – 530 | Missing in isoform 3. 1 PublicationAdd BLAST | 447 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK037211 mRNA Translation: BAC29755.1 Sequence problems. BC060530 mRNA Translation: AAH60530.1 AK129467 mRNA Translation: BAC98277.1 |
CCDSi | CCDS39876.1 [Q6P9Y7-1] CCDS59724.1 [Q6P9Y7-3] |
RefSeqi | NP_001239448.1, NM_001252519.1 NP_001240314.1, NM_001253385.1 [Q6P9Y7-3] NP_808557.2, NM_177889.5 [Q6P9Y7-1] |
Genome annotation databases
Ensembli | ENSMUST00000080834; ENSMUSP00000079647; ENSMUSG00000098022 [Q6P9Y7-1] ENSMUST00000183190; ENSMUSP00000138469; ENSMUSG00000098022 [Q6P9Y7-3] |
GeneIDi | 330502 |
KEGGi | mmu:330502 |
UCSCi | uc009gcz.2, mouse [Q6P9Y7-1] uc009gdc.2, mouse [Q6P9Y7-3] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK037211 mRNA Translation: BAC29755.1 Sequence problems. BC060530 mRNA Translation: AAH60530.1 AK129467 mRNA Translation: BAC98277.1 |
CCDSi | CCDS39876.1 [Q6P9Y7-1] CCDS59724.1 [Q6P9Y7-3] |
RefSeqi | NP_001239448.1, NM_001252519.1 NP_001240314.1, NM_001253385.1 [Q6P9Y7-3] NP_808557.2, NM_177889.5 [Q6P9Y7-1] |
3D structure databases
SMRi | Q6P9Y7 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 236978, 2 interactors |
IntActi | Q6P9Y7, 2 interactors |
STRINGi | 10090.ENSMUSP00000079647 |
PTM databases
PhosphoSitePlusi | Q6P9Y7 |
Proteomic databases
MaxQBi | Q6P9Y7 |
PaxDbi | Q6P9Y7 |
PRIDEi | Q6P9Y7 |
ProteomicsDBi | 274988 [Q6P9Y7-1] 274989 [Q6P9Y7-2] |
Protocols and materials databases
Antibodypediai | 16307, 130 antibodies from 20 providers |
DNASUi | 330502 |
Genome annotation databases
Ensembli | ENSMUST00000080834; ENSMUSP00000079647; ENSMUSG00000098022 [Q6P9Y7-1] ENSMUST00000183190; ENSMUSP00000138469; ENSMUSG00000098022 [Q6P9Y7-3] |
GeneIDi | 330502 |
KEGGi | mmu:330502 |
UCSCi | uc009gcz.2, mouse [Q6P9Y7-1] uc009gdc.2, mouse [Q6P9Y7-3] |
Organism-specific databases
CTDi | 284406 |
MGIi | MGI:1890753, Zfp82 |
VEuPathDBi | HostDB:ENSMUSG00000098022 |
Rougei | Search... |
Phylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000162531 |
HOGENOMi | CLU_002678_69_8_1 |
InParanoidi | Q6P9Y7 |
OMAi | QHQSIHV |
OrthoDBi | 1318335at2759 |
PhylomeDBi | Q6P9Y7 |
TreeFami | TF341817 |
Miscellaneous databases
BioGRID-ORCSi | 330502, 2 hits in 66 CRISPR screens |
ChiTaRSi | Zfp82, mouse |
PROi | PR:Q6P9Y7 |
RNActi | Q6P9Y7, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000098022, Expressed in testis and 77 other tissues |
Genevisiblei | Q6P9Y7, MM |
Family and domain databases
CDDi | cd07765, KRAB_A-box, 1 hit |
InterProi | View protein in InterPro IPR001909, KRAB IPR036051, KRAB_dom_sf IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF01352, KRAB, 1 hit PF00096, zf-C2H2, 10 hits |
SMARTi | View protein in SMART SM00349, KRAB, 1 hit SM00355, ZnF_C2H2, 13 hits |
SUPFAMi | SSF109640, SSF109640, 1 hit SSF57667, SSF57667, 7 hits |
PROSITEi | View protein in PROSITE PS50805, KRAB, 1 hit PS00028, ZINC_FINGER_C2H2_1, 12 hits PS50157, ZINC_FINGER_C2H2_2, 13 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | ZFP82_MOUSE | |
Accessioni | Q6P9Y7Primary (citable) accession number: Q6P9Y7 Secondary accession number(s): Q6ZPG0, Q8BIP1 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 2, 2006 |
Last sequence update: | July 5, 2004 | |
Last modified: | February 23, 2022 | |
This is version 138 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot - SIMILARITY comments
Index of protein domains and families