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Entry version 143 (07 Apr 2021)
Sequence version 2 (02 Oct 2007)
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Protein

Zinc finger protein 530

Gene

ZNF530

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri239 – 261C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri267 – 289C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri295 – 317C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri323 – 345C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri351 – 373C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri379 – 401C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri407 – 429C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri435 – 457C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri463 – 485C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri491 – 513C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri519 – 541C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri547 – 569C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri575 – 597C2H2-type 13PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q6P9A1

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-212436, Generic Transcription Pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 530
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF530
Synonyms:KIAA1508
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:29297, ZNF530

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q6P9A1

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000183647.10

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
348327

Open Targets

More...
OpenTargetsi
ENSG00000183647

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134892909

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q6P9A1, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZNF530

Domain mapping of disease mutations (DMDM)

More...
DMDMi
158706493

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003049971 – 599Zinc finger protein 530Add BLAST599

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q6P9A1

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q6P9A1

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q6P9A1

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q6P9A1

PeptideAtlas

More...
PeptideAtlasi
Q6P9A1

PRoteomics IDEntifications database

More...
PRIDEi
Q6P9A1

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
67030

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q6P9A1

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q6P9A1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000183647, Expressed in secondary oocyte and 128 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q6P9A1, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q6P9A1, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000183647, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
131520, 1 interactor

Protein interaction database and analysis system

More...
IntActi
Q6P9A1, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000332861

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q6P9A1, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q6P9A1

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini14 – 94KRABPROSITE-ProRule annotationAdd BLAST81

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri239 – 261C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri267 – 289C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri295 – 317C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri323 – 345C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri351 – 373C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri379 – 401C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri407 – 429C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri435 – 457C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri463 – 485C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri491 – 513C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri519 – 541C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri547 – 569C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri575 – 597C2H2-type 13PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1721, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000164722

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_002678_57_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q6P9A1

Identification of Orthologs from Complete Genome Data

More...
OMAi
CEICTPV

Database of Orthologous Groups

More...
OrthoDBi
1318335at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q6P9A1

TreeFam database of animal gene trees

More...
TreeFami
TF339848

Family and domain databases

Conserved Domains Database

More...
CDDi
cd07765, KRAB_A-box, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001909, KRAB
IPR036051, KRAB_dom_sf
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01352, KRAB, 1 hit
PF00096, zf-C2H2, 11 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00349, KRAB, 1 hit
SM00355, ZnF_C2H2, 13 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF109640, SSF109640, 1 hit
SSF57667, SSF57667, 8 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50805, KRAB, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 13 hits
PS50157, ZINC_FINGER_C2H2_2, 13 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q6P9A1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAALRAPTQ QVFVAFEDVA IYFSQEEWEL LDEMQRLLYR DVMLENFAVM
60 70 80 90 100
ASLGCWCGAV DEGTPSAESV SVEELSQGRT PKADTSTDKS HPCEICTPVL
110 120 130 140 150
RDILQMIELH ASPCGQKLYL GGASRDFWMS SNLHQLQKLD NGEKLFKVDG
160 170 180 190 200
DQASFMMNCR FHVSGKPFTF GEVGRDFSAT SGLLQHQVTP TIERPHSRIR
210 220 230 240 250
HLRVPTGRKP LKYTESRKSF REKSVFIQHQ RADSGERPYK CSECGKSFSQ
260 270 280 290 300
SSGFLRHRKA HGRTRTHECS ECGKSFSRKT HLTQHQRVHT GERPYDCSEC
310 320 330 340 350
GKSFRQVSVL IQHQRVHTGE RPYECSECGK SFSHSTNLYR HRSAHTSTRP
360 370 380 390 400
YECSECGKSF SHSTNLFRHW RVHTGVRPYE CSECGKAFSC NIYLIHHQRF
410 420 430 440 450
HTGERPYVCS ECGKSFGQKS VLIQHQRVHT GERPYECSEC GKVFSQSSGL
460 470 480 490 500
FRHRRAHTKT KPYECSECEK SFSCKTDLIR HQTVHTGERP YECSVCGKSF
510 520 530 540 550
IRKTHLIRHQ TVHTNERPYE CDECGKSYSQ SSALLQHRRV HTGERPYECR
560 570 580 590
ECGKSFTRKN HLIQHKTVHT GERPYECSEC GKSFSQSSGL LRHRRVHVQ
Length:599
Mass (Da):68,837
Last modified:October 2, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4A1E04810B74CEF2
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
M0R0Y5M0R0Y5_HUMAN
Zinc finger protein 530
ZNF530
28Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M0R1P0M0R1P0_HUMAN
Zinc finger protein 530
ZNF530
32Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAC24609 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence BAA96032 differs from that shown. Intron retention.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_03514464T → A1 PublicationCorresponds to variant dbSNP:rs9677004Ensembl.1
Natural variantiVAR_035145110H → Q2 PublicationsCorresponds to variant dbSNP:rs2360543Ensembl.1
Natural variantiVAR_035146124S → P1 PublicationCorresponds to variant dbSNP:rs17855076Ensembl.1
Natural variantiVAR_035147169T → M. Corresponds to variant dbSNP:rs11883343Ensembl.1
Natural variantiVAR_035148262G → S. Corresponds to variant dbSNP:rs9676259Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC003682 Genomic DNA Translation: AAC24609.1 Sequence problems.
BC060865 mRNA Translation: AAH60865.1
AB040941 mRNA Translation: BAA96032.1 Sequence problems.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS12955.1

NCBI Reference Sequences

More...
RefSeqi
NP_001308910.1, NM_001321981.1
NP_065931.3, NM_020880.4

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000332854; ENSP00000332861; ENSG00000183647
ENST00000600619; ENSP00000472564; ENSG00000183647

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
348327

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:348327

UCSC genome browser

More...
UCSCi
uc002qpk.3, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC003682 Genomic DNA Translation: AAC24609.1 Sequence problems.
BC060865 mRNA Translation: AAH60865.1
AB040941 mRNA Translation: BAA96032.1 Sequence problems.
CCDSiCCDS12955.1
RefSeqiNP_001308910.1, NM_001321981.1
NP_065931.3, NM_020880.4

3D structure databases

SMRiQ6P9A1
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi131520, 1 interactor
IntActiQ6P9A1, 1 interactor
STRINGi9606.ENSP00000332861

PTM databases

iPTMnetiQ6P9A1
PhosphoSitePlusiQ6P9A1

Genetic variation databases

BioMutaiZNF530
DMDMi158706493

Proteomic databases

EPDiQ6P9A1
MassIVEiQ6P9A1
MaxQBiQ6P9A1
PaxDbiQ6P9A1
PeptideAtlasiQ6P9A1
PRIDEiQ6P9A1
ProteomicsDBi67030

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
33274, 87 antibodies

The DNASU plasmid repository

More...
DNASUi
348327

Genome annotation databases

EnsembliENST00000332854; ENSP00000332861; ENSG00000183647
ENST00000600619; ENSP00000472564; ENSG00000183647
GeneIDi348327
KEGGihsa:348327
UCSCiuc002qpk.3, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
348327
DisGeNETi348327

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ZNF530
HGNCiHGNC:29297, ZNF530
HPAiENSG00000183647, Low tissue specificity
neXtProtiNX_Q6P9A1
OpenTargetsiENSG00000183647
PharmGKBiPA134892909
VEuPathDBiHostDB:ENSG00000183647.10

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1721, Eukaryota
GeneTreeiENSGT00940000164722
HOGENOMiCLU_002678_57_1_1
InParanoidiQ6P9A1
OMAiCEICTPV
OrthoDBi1318335at2759
PhylomeDBiQ6P9A1
TreeFamiTF339848

Enzyme and pathway databases

PathwayCommonsiQ6P9A1
ReactomeiR-HSA-212436, Generic Transcription Pathway

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
348327, 3 hits in 1018 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
348327
PharosiQ6P9A1, Tdark

Protein Ontology

More...
PROi
PR:Q6P9A1
RNActiQ6P9A1, protein

Gene expression databases

BgeeiENSG00000183647, Expressed in secondary oocyte and 128 other tissues
ExpressionAtlasiQ6P9A1, baseline and differential
GenevisibleiQ6P9A1, HS

Family and domain databases

CDDicd07765, KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909, KRAB
IPR036051, KRAB_dom_sf
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF01352, KRAB, 1 hit
PF00096, zf-C2H2, 11 hits
SMARTiView protein in SMART
SM00349, KRAB, 1 hit
SM00355, ZnF_C2H2, 13 hits
SUPFAMiSSF109640, SSF109640, 1 hit
SSF57667, SSF57667, 8 hits
PROSITEiView protein in PROSITE
PS50805, KRAB, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 13 hits
PS50157, ZINC_FINGER_C2H2_2, 13 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN530_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6P9A1
Secondary accession number(s): O43340, Q9P220
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 2, 2007
Last sequence update: October 2, 2007
Last modified: April 7, 2021
This is version 143 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. SIMILARITY comments
    Index of protein domains and families
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