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Protein
Submitted name:

Opn1sw1 protein

Gene

opn1sw1

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotationSAAS annotation, Photoreceptor protein, Receptor, Retinal proteinUniRule annotation, Transducer
Biological process
LigandChromophore

Enzyme and pathway databases

ReactomeiR-DRE-2187335 The retinoid cycle in cones (daylight vision)
R-DRE-418594 G alpha (i) signalling events
R-DRE-419771 Opsins

Names & Taxonomyi

Protein namesi
Submitted name:
Opn1sw1 proteinImported
Submitted name:
Opsin 1 (Cone pigments), short-wave-sensitive 1Imported
Submitted name:
Opsin-1, short-wave-sensitive 1Imported
Submitted name:
Short-wavelength-sensitive-1 cone opsinImported
Gene namesi
Name:opn1sw1Imported
Synonyms:sws1Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 4

Organism-specific databases

ZFINiZDB-GENE-991109-25 opn1sw1

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei30 – 55HelicalUniRule annotationAdd BLAST26
Transmembranei67 – 89HelicalUniRule annotationAdd BLAST23
Transmembranei95 – 126HelicalUniRule annotationAdd BLAST32
Transmembranei146 – 166HelicalUniRule annotationAdd BLAST21
Transmembranei196 – 216HelicalUniRule annotationAdd BLAST21
Transmembranei247 – 269HelicalUniRule annotationAdd BLAST23
Transmembranei281 – 302HelicalUniRule annotationAdd BLAST22

Keywords - Cellular componenti

Membrane

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSDARG00000045677 Expressed in 12 organ(s), highest expression level in head

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini47 – 299G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST253

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3656 Eukaryota
ENOG410XRW9 LUCA
GeneTreeiENSGT00760000118977
HOVERGENiHBG107442
OMAiACIMEMV
OrthoDBiEOG091G0BDA
TreeFamiTF324998

Family and domain databases

InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR001760 Opsin
IPR001521 Opsin_blue
IPR027430 Retinal_BS
PfamiView protein in Pfam
PF00001 7tm_1, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PR00238 OPSIN
PR00574 OPSINBLUE
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit
PS00238 OPSIN, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q6P981-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDAWAVQFGN ASKVSPFEGE QYHIAPKWAF YLQAAFMGFV FIVGTPMNGI
60 70 80 90 100
VLFVTMKYKK LRQPLNYILV NISLAGFIFD TFSVSQVFVC AARGYYFLGY
110 120 130 140 150
TLCAMEAAMG SIAGLVTGWS LAVLAFERYV VICKPFGSFK FGQGQAVGAV
160 170 180 190 200
VFTWIIGTAC ATPPFFGWSR YIPEGLGTAC GPDWYTKSEE YNSESYTYFL
210 220 230 240 250
LVTCFMMPMT IIIFSYSQLL GALRAVAAQQ AESESTQKAE REVSRMVVVM
260 270 280 290 300
VGSFVLCYAP YAVTAMYFAN SDEPNKDYRL VAIPAFFSKS SCVYNPLIYA
310 320 330
FMNKQFNACI METVFGKKID ESSEVSSKTE TSSVSA
Length:336
Mass (Da):37,254
Last modified:July 5, 2004 - v1
Checksum:i15CC7D4AC5C268A0
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9W6A9OP1S1_DANRE
Opsin-1, short-wave-sensitive 1
opn1sw1 opn1sw2, sws1, uvops
336Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX465210 Genomic DNA No translation available.
BC060894 mRNA Translation: AAH60894.1
BC153466 mRNA Translation: AAI53467.1
KT008399 mRNA Translation: ALG92539.1
UniGeneiDr.8194

Genome annotation databases

EnsembliENSDART00000067160; ENSDARP00000067159; ENSDARG00000045677

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX465210 Genomic DNA No translation available.
BC060894 mRNA Translation: AAH60894.1
BC153466 mRNA Translation: AAI53467.1
KT008399 mRNA Translation: ALG92539.1
UniGeneiDr.8194

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000067160; ENSDARP00000067159; ENSDARG00000045677

Organism-specific databases

ZFINiZDB-GENE-991109-25 opn1sw1

Phylogenomic databases

eggNOGiKOG3656 Eukaryota
ENOG410XRW9 LUCA
GeneTreeiENSGT00760000118977
HOVERGENiHBG107442
OMAiACIMEMV
OrthoDBiEOG091G0BDA
TreeFamiTF324998

Enzyme and pathway databases

ReactomeiR-DRE-2187335 The retinoid cycle in cones (daylight vision)
R-DRE-418594 G alpha (i) signalling events
R-DRE-419771 Opsins

Gene expression databases

BgeeiENSDARG00000045677 Expressed in 12 organ(s), highest expression level in head

Family and domain databases

InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR001760 Opsin
IPR001521 Opsin_blue
IPR027430 Retinal_BS
PfamiView protein in Pfam
PF00001 7tm_1, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PR00238 OPSIN
PR00574 OPSINBLUE
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit
PS00238 OPSIN, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ6P981_DANRE
AccessioniPrimary (citable) accession number: Q6P981
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: November 7, 2018
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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