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Protein
Submitted name:

ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial

Gene

Clpx

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrialImported
Submitted name:
Caseinolytic peptidase X (E.coli)Imported
Gene namesi
Name:ClpxImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 9

Organism-specific databases

MGIiMGI:1346017 Clpx

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000015357 Expressed in 271 organ(s), highest expression level in liver

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini272 – 423AAAInterPro annotationAdd BLAST152
Domaini496 – 590ClpB_D2-smallInterPro annotationAdd BLAST95

Phylogenomic databases

eggNOGiKOG0745 Eukaryota
COG1219 LUCA
GeneTreeiENSGT00390000017625
HOGENOMiHOG000010093
HOVERGENiHBG004940

Family and domain databases

InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR003959 ATPase_AAA_core
IPR019489 Clp_ATPase_C
IPR004487 Clp_protease_ATP-bd_su_ClpX
IPR027417 P-loop_NTPase
PANTHERiPTHR11262 PTHR11262, 1 hit
PfamiView protein in Pfam
PF07724 AAA_2, 1 hit
PF10431 ClpB_D2-small, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SM01086 ClpB_D2-small, 1 hit
SUPFAMiSSF52540 SSF52540, 2 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.iShow all

Q6P8N8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSCGACTCG AAAARLLTTS LTSAQRGISC GRIHVPVLGR LGTTLDAQAL
60 70 80 90 100
RRAPLRTFSE TPAYFASKDG ANKDGSGDGN KKSVTEGSSK KSGSGNSGKG
110 120 130 140 150
GNQLRCPKCG DLCTHVETFV SSTRFVKCEK CHHFFVVLSE ADSKKSIIKE
160 170 180 190 200
PESAAEAVKL AFQQKPPPPP KKIYNYLDKY VVGQSFAKKV LSVAVYNHYK
210 220 230 240 250
RIYNNIPANL RQQAEAEKQT SLTPRELLQI AGISPHGNAL GASMQQQVNQ
260 270 280 290 300
QMPQEKRGGE VLDSSQDDIK LEKSNILLLG PTGSGKTLLA QTLAKCLDVP
310 320 330 340 350
FAICDCTTLT QAGYVGEDIE SVIAKLLQDA NYNVEKAQQG IVFLDEVDKI
360 370 380 390 400
GSVPGIHQLR DVGGEGVQQG LLKLLEGTIV NVPEKNSRKL RGETVQVDTT
410 420 430 440 450
NVLFVASGAF NGLDRIISRR KNEKYLGFGT PSNLGKGRRA AAAADLANRS
460 470 480 490 500
GESNTHQDIE EKDRLLRHVE ARDLIEFGMI PEFVGRLPVV VPLHSLDEKT
510 520 530 540 550
LVQILTEPRN AVIPQYQALF SMDKCELNVT EDALKAIARL ALERKTGARG
560 570 580 590 600
LRSIMEKLLL EPMFEVPNSD IVCVEVDKEV VEGKKEPGYI RAPSKESSEE
610 620
EYDSGVEEDG WPRQADAANS
Length:620
Mass (Da):67,336
Last modified:July 5, 2004 - v1
Checksum:i44D82B9F5AE6F81C
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9JHS4CLPX_MOUSE
ATP-dependent Clp protease ATP-bind...
Clpx
634Annotation score:
F7BB92F7BB92_MOUSE
ATP-dependent Clp protease ATP-bind...
Clpx
192Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC110235 Genomic DNA No translation available.
BC061153 mRNA Translation: AAH61153.1
RefSeqiNP_001037854.1, NM_001044389.2
UniGeneiMm.30088

Genome annotation databases

EnsembliENSMUST00000113824; ENSMUSP00000109455; ENSMUSG00000015357
GeneIDi270166
UCSCiuc009qdc.2 mouse

Similar proteinsi

Entry informationi

Entry nameiQ6P8N8_MOUSE
AccessioniPrimary (citable) accession number: Q6P8N8
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: September 12, 2018
This is version 125 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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