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Protein

Mitochondrial import receptor subunit TOM40 homolog

Gene

tomm40

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Channel-forming protein essential for import of protein precursors into mitochondria.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionPorin
Biological processIon transport, Protein transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Mitochondrial import receptor subunit TOM40 homolog
Alternative name(s):
Translocase of outer membrane 40 kDa subunit homolog
Gene namesi
Name:tomm40
OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Taxonomic identifieri8364 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana
Proteomesi
  • UP000008143 Componenti: Unassembled WGS sequence

Organism-specific databases

XenbaseiXB-GENE-995150 tomm40

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion outer membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000515271 – 336Mitochondrial import receptor subunit TOM40 homologAdd BLAST336

Proteomic databases

PaxDbiQ6P825
PRIDEiQ6P825

Interactioni

Subunit structurei

Forms part of the preprotein translocase complex of the outer mitochondrial membrane (TOM complex). Interacts with mitochondrial targeting sequences (By similarity).By similarity

Protein-protein interaction databases

STRINGi8364.ENSXETP00000041847

Structurei

3D structure databases

SMRiQ6P825
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Tom40 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane beta strand

Phylogenomic databases

eggNOGiKOG3296 Eukaryota
ENOG410XS2U LUCA
HOGENOMiHOG000007440
HOVERGENiHBG054707
InParanoidiQ6P825
KOiK11518

Family and domain databases

CDDicd07305 Porin3_Tom40, 1 hit
Gene3Di2.40.160.10, 1 hit
InterProiView protein in InterPro
IPR023614 Porin_dom_sf
IPR027246 Porin_Euk/Tom40
IPR037930 Tom40
PANTHERiPTHR10802 PTHR10802, 1 hit
PfamiView protein in Pfam
PF01459 Porin_3, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q6P825-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGNVLAASSP APPAAGSPPA PGLVSVPPGF TMPPVAGLTP TPDKKETQED
60 70 80 90 100
RLPNPGTFEE CHRKCKELFP IQMEGVKLTV NKGLSNYFQV NHTVSLSMIG
110 120 130 140 150
ESNYHFGATY VGTKQLGPAE AFPVLVGDLD NSGSLNAQII HQVTSNVRSK
160 170 180 190 200
IALQTQQSKF VNWQLDTEYR GEDFTAAVTL GNPDILVGSG ILVAHYLQSI
210 220 230 240 250
TPSLALGGEL VYHRRPGEEG TVMSLAGRYT APNWTATLTL GQAGAHATYY
260 270 280 290 300
HKANDQLQVG VEFEASTRMQ DTSVSFGYQL DLPKANLLFK GSVDSNWIVG
310 320 330
ATLEKKLPPL PLTLAMGAFL NHKKNKFQCG FGLTIG
Length:336
Mass (Da):36,039
Last modified:July 5, 2004 - v1
Checksum:i2D0FD7B7A88BE30F
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F6V8B8F6V8B8_XENTR
Mitochondrial import receptor subun...
tomm40
283Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC061406 mRNA Translation: AAH61406.1
RefSeqiNP_989125.1, NM_203794.1
UniGeneiStr.6655

Genome annotation databases

GeneIDi394730
KEGGixtr:394730

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC061406 mRNA Translation: AAH61406.1
RefSeqiNP_989125.1, NM_203794.1
UniGeneiStr.6655

3D structure databases

SMRiQ6P825
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi8364.ENSXETP00000041847

Proteomic databases

PaxDbiQ6P825
PRIDEiQ6P825

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi394730
KEGGixtr:394730

Organism-specific databases

CTDi10452
XenbaseiXB-GENE-995150 tomm40

Phylogenomic databases

eggNOGiKOG3296 Eukaryota
ENOG410XS2U LUCA
HOGENOMiHOG000007440
HOVERGENiHBG054707
InParanoidiQ6P825
KOiK11518

Family and domain databases

CDDicd07305 Porin3_Tom40, 1 hit
Gene3Di2.40.160.10, 1 hit
InterProiView protein in InterPro
IPR023614 Porin_dom_sf
IPR027246 Porin_Euk/Tom40
IPR037930 Tom40
PANTHERiPTHR10802 PTHR10802, 1 hit
PfamiView protein in Pfam
PF01459 Porin_3, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiTOM40_XENTR
AccessioniPrimary (citable) accession number: Q6P825
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 7, 2006
Last sequence update: July 5, 2004
Last modified: April 25, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health

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