UniProtKB - Q6P6U2 (Q6P6U2_RAT)
Protein
Submitted name:
26S proteasome regulatory subunit 6A
Gene
Psmc3
Organism
Rattus norvegicus (Rat)
Status
Functioni
GO - Molecular functioni
- ATPase activity Source: InterPro
- ATP binding Source: UniProtKB-KW
- identical protein binding Source: Ensembl
GO - Biological processi
- blastocyst development Source: Ensembl
- modulation by host of viral transcription Source: Ensembl
- positive regulation of transcription by RNA polymerase II Source: Ensembl
- protein catabolic process Source: InterPro
Keywordsi
Ligand | ATP-bindingUniRule annotation, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Submitted name: 26S proteasome regulatory subunit 6AImportedSubmitted name: Proteasome (Prosome, macropain) 26S subunit, ATPase 3ImportedSubmitted name: Proteasome (Prosome, macropain) 26S subunit, ATPase 3, isoform CRA_aImported |
Gene namesi | Name:Psmc3Imported ORF Names:rCG_27374Imported |
Organismi | Rattus norvegicus (Rat)Imported |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 61905, Psmc3 |
Subcellular locationi
Nucleus
- nucleus Source: UniProtKB-SubCell
Other locations
- P-body Source: Ensembl
- proteasome accessory complex Source: Ensembl
Keywords - Cellular componenti
NucleusARBA annotation, ProteasomeImportedARBA annotationExpressioni
Gene expression databases
Bgeei | ENSRNOG00000011414, Expressed in testis and 22 other tissues |
Interactioni
GO - Molecular functioni
- identical protein binding Source: Ensembl
Protein-protein interaction databases
IntActi | Q6P6U2, 1 interactor |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 222 – 361 | AAAInterPro annotationAdd BLAST | 140 |
Sequence similaritiesi
Phylogenomic databases
GeneTreei | ENSGT01000000214468 |
HOGENOMi | CLU_000688_2_4_1 |
OMAi | KPTEQYT |
Family and domain databases
InterProi | View protein in InterPro IPR005937, 26S_Psome_P45-like IPR003593, AAA+_ATPase IPR041569, AAA_lid_3 IPR003959, ATPase_AAA_core IPR003960, ATPase_AAA_CS IPR027417, P-loop_NTPase IPR032501, Prot_ATP_ID_OB |
Pfami | View protein in Pfam PF00004, AAA, 1 hit PF17862, AAA_lid_3, 1 hit PF16450, Prot_ATP_ID_OB, 1 hit |
SMARTi | View protein in SMART SM00382, AAA, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
TIGRFAMsi | TIGR01242, 26Sp45, 1 hit |
PROSITEi | View protein in PROSITE PS00674, AAA, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
Q6P6U2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MQEMNLLPTP ESPVTRQEKM ATVWDEAEQD GIGEEVLKMS TEEIVQRTRL
60 70 80 90 100
LDSEIKIMKS EVLRVTHELQ AMKDKIKENS EKIKVNKTLP YLVSNVIELL
110 120 130 140 150
DVDPNDQEED GANIDLDSQR KGKCAVIKTS TRQTYFLPVI GLVDAEKLKP
160 170 180 190 200
GDLVGVNKDS YLILETLPTE YDSRVKAMEV DERPTEQYSD IGGLDKQIQE
210 220 230 240 250
LVEAIVLPMN HKEKFENLGI QPPKGVLMYG PPGTGKTLLA RACAAQTKAT
260 270 280 290 300
FLKLAGPQLV QMFIGDGAKL VRDAFALAKE KAPSIIFIDE LDAIGTKRFD
310 320 330 340 350
SEKAGDREVQ RTMLELLNQL DGFQPNTQVK VIAATNRVDI LDPALLRSGR
360 370 380 390 400
LDRKIEFPMP NEEARARIMQ IHSRKMNVSP DVNYEELARC TDDFNGAQCK
410 420 430 440
AVCVEAGMIA LRRGATELTH EDYMEGILEV QAKKKANLQY YA
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketQ63569 | PRS6A_RAT | 26S proteasome regulatory subunit 6... | Psmc3 Tbp1 | 439 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AABR07052865 Genomic DNA No translation available. BC062019 mRNA Translation: AAH62019.1 CH473949 Genomic DNA Translation: EDL79502.1 |
Genome annotation databases
Ensembli | ENSRNOT00000015757; ENSRNOP00000015757; ENSRNOG00000011414 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AABR07052865 Genomic DNA No translation available. BC062019 mRNA Translation: AAH62019.1 CH473949 Genomic DNA Translation: EDL79502.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
IntActi | Q6P6U2, 1 interactor |
Genome annotation databases
Ensembli | ENSRNOT00000015757; ENSRNOP00000015757; ENSRNOG00000011414 |
Organism-specific databases
RGDi | 61905, Psmc3 |
Phylogenomic databases
GeneTreei | ENSGT01000000214468 |
HOGENOMi | CLU_000688_2_4_1 |
OMAi | KPTEQYT |
Gene expression databases
Bgeei | ENSRNOG00000011414, Expressed in testis and 22 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR005937, 26S_Psome_P45-like IPR003593, AAA+_ATPase IPR041569, AAA_lid_3 IPR003959, ATPase_AAA_core IPR003960, ATPase_AAA_CS IPR027417, P-loop_NTPase IPR032501, Prot_ATP_ID_OB |
Pfami | View protein in Pfam PF00004, AAA, 1 hit PF17862, AAA_lid_3, 1 hit PF16450, Prot_ATP_ID_OB, 1 hit |
SMARTi | View protein in SMART SM00382, AAA, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
TIGRFAMsi | TIGR01242, 26Sp45, 1 hit |
PROSITEi | View protein in PROSITE PS00674, AAA, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q6P6U2_RAT | |
Accessioni | Q6P6U2Primary (citable) accession number: Q6P6U2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 5, 2004 |
Last sequence update: | July 5, 2004 | |
Last modified: | December 2, 2020 | |
This is version 141 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |