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Entry version 143 (02 Jun 2021)
Sequence version 1 (05 Jul 2004)
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Protein

ADP-ribosylation factor-binding protein GGA2

Gene

Gga2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (DXXLL) motif. Mediates export of the GPCR receptor ADRA2B to the cell surface. Regulates retrograde transport of phosphorylated form of BACE1 from endosomes to the trans-Golgi network.

By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processProtein transport, Transport

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
ADP-ribosylation factor-binding protein GGA2
Alternative name(s):
Gamma-adaptin-related protein 2
Golgi-localized, gamma ear-containing, ARF-binding protein 2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Gga2
Synonyms:Kiaa1080
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1921355, Gga2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Endosome, Golgi apparatus, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002126831 – 603ADP-ribosylation factor-binding protein GGA2Add BLAST603

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Ubiquitinated.By similarity

Keywords - PTMi

Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q6P5E6

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q6P5E6

PeptideAtlas

More...
PeptideAtlasi
Q6P5E6

PRoteomics IDEntifications database

More...
PRIDEi
Q6P5E6

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
267434 [Q6P5E6-1]
267435 [Q6P5E6-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q6P5E6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q6P5E6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000030872, Expressed in ear and 313 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q6P5E6, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Monomer (By similarity).

Interacts with NECAP1, TSG101, UBC and AFTPH/aftiphilin.

Interacts with CNST (PubMed:19864490).

Interacts with GGA1 and GGA3 (By similarity). Binds to clathrin and activated ARFs, such as ARF1, ARF5 and ARF6 (PubMed:11950392). Binds RABEP1 and RABGEF1.

Interacts with the type-I membrane proteins LRP3, M6PR/CD-MPR, IGF2R/CI-MPR and BACE1.

Interacts (via N-terminal VHS domain) with SORL1/sorLA and SORT1 (via C-terminal cytosolic domain) (By similarity). Binds the accessory proteins CCDC91, P200, SYNRG, EPN4 and NECAP2.

Interacts with ADRA2B.

Interacts (via VHS domain) with PIK4B; the interaction is important for PIK4B location at the Golgi apparatus membrane (By similarity).

By similarity2 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

GO - Molecular functioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q6P5E6, 3 interactors

Molecular INTeraction database

More...
MINTi
Q6P5E6

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000033160

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q6P5E6, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q6P5E6

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini36 – 166VHSPROSITE-ProRule annotationAdd BLAST131
Domaini190 – 317GATPROSITE-ProRule annotationAdd BLAST128
Domaini474 – 595GAEPROSITE-ProRule annotationAdd BLAST122

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 22DisorderedSequence analysisAdd BLAST22
Regioni318 – 473Unstructured hingeAdd BLAST156

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The VHS domain functions as a recognition module for sorting signals composed of an acidic cluster followed by two leucines (DXXLL motif).By similarity
The GAT domain is responsible for interaction with ARF-GTP, UBC and RABEP1. Required for recruitment to the TGN it prevents ARF-GTP hydrolysis.By similarity
The unstructured hinge region contains clathrin-binding but no autoinhibitory (DXXLL) motifs.By similarity
The GAE domain binds accessory proteins regulating GGAs function.By similarity

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the GGA protein family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1086, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000159613

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_015010_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q6P5E6

Identification of Orthologs from Complete Genome Data

More...
OMAi
KVAGQNC

Database of Orthologous Groups

More...
OrthoDBi
594067at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q6P5E6

TreeFam database of animal gene trees

More...
TreeFami
TF318574

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.58.160, 1 hit
1.25.40.90, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR008152, Clathrin_a/b/g-adaptin_app_Ig
IPR013041, Clathrin_app_Ig-like_sf
IPR008942, ENTH_VHS
IPR008153, GAE_dom
IPR004152, GAT_dom
IPR038425, GAT_sf
IPR041198, GGA_N-GAT
IPR002014, VHS_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02883, Alpha_adaptinC2, 1 hit
PF03127, GAT, 1 hit
PF18308, GGA_N-GAT, 1 hit
PF00790, VHS, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00809, Alpha_adaptinC2, 1 hit
SM00288, VHS, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48464, SSF48464, 1 hit
SSF49348, SSF49348, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50180, GAE, 1 hit
PS50909, GAT, 1 hit
PS50179, VHS, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q6P5E6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAATAVAAGT GSPAGTESAE GGPGAAAALE LWLNKATDPS MAEQDWSAIQ
60 70 80 90 100
KFCEQVNTDP SGPTHAPWLL AHKIQSPQEK EALYALTVLE ICMNHCGEKF
110 120 130 140 150
HSEVAKFRFL NELIKVLSPK YLGAWATEKV KGRVIEILFS WTVWFPEDIK
160 170 180 190 200
IRDAYQMLKK QGIIKQDPKL PMDKILPPPS PWPKSIFDAD EEKSKLLTRL
210 220 230 240 250
LKSNHPEDLQ AANRLIKNLV KEEQEKSEKV SRRVSAVEEV RSHVRVLREM
260 270 280 290 300
LSMYRRPGHA LPDQQALQVV YERCEKLRPT LFRLASDTTD DDDALAEILQ
310 320 330 340 350
ANDLLTQGVR LYKQVVEGRV SAGNAVPAAV GAIPAPRAFP NPEPCGLNCP
360 370 380 390 400
LIDLETPSLL HQDLAALGIN DVPTRNQVVI PSCCNDKKQP GAITLMGGGI
410 420 430 440 450
QSLSADRNLL DLFSPQPSPG LNYVPQKSIP KEVPPGTKAS PGWSWEAGPL
460 470 480 490 500
ASSTASQNTP LAHVFVPLES VKPSSLPPIV VYDRNGFRIL LHFSQTGAPG
510 520 530 540 550
HPDVKVLLLT MMSTATQPVW DVMFQVAVPK SMRVKLQPAS SSKLPAFSPL
560 570 580 590 600
MPPAVISQTL LLDNPHKEPI RLRYKLTFNQ GGQPFSEVGE VKDFPDLAVL

STA
Length:603
Mass (Da):66,049
Last modified:July 5, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0EFCB3905074982C
GO
Isoform 2 (identifier: Q6P5E6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-249: Missing.

Show »
Length:354
Mass (Da):38,178
Checksum:iE54F3C332CD2C392
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAC28769 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated
The sequence BAC98090 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti228E → G in BAB23426 (PubMed:16141072).Curated1
Sequence conflicti499P → A in BAB23426 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0132551 – 249Missing in isoform 2. 1 PublicationAdd BLAST249

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK004632 mRNA Translation: BAB23426.1
AK034612 mRNA Translation: BAC28769.1 Different initiation.
AK129280 mRNA Translation: BAC98090.1 Different initiation.
AK143691 mRNA Translation: BAE25501.1
AK154904 mRNA Translation: BAE32915.1
BC057377 mRNA Translation: AAH57377.1
BC062933 mRNA Translation: AAH62933.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS40116.1 [Q6P5E6-1]

NCBI Reference Sequences

More...
RefSeqi
NP_083034.1, NM_028758.2 [Q6P5E6-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000033160; ENSMUSP00000033160; ENSMUSG00000030872 [Q6P5E6-1]
ENSMUST00000124566; ENSMUSP00000115581; ENSMUSG00000030872 [Q6P5E6-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
74105

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:74105

UCSC genome browser

More...
UCSCi
uc009joa.1, mouse [Q6P5E6-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK004632 mRNA Translation: BAB23426.1
AK034612 mRNA Translation: BAC28769.1 Different initiation.
AK129280 mRNA Translation: BAC98090.1 Different initiation.
AK143691 mRNA Translation: BAE25501.1
AK154904 mRNA Translation: BAE32915.1
BC057377 mRNA Translation: AAH57377.1
BC062933 mRNA Translation: AAH62933.1
CCDSiCCDS40116.1 [Q6P5E6-1]
RefSeqiNP_083034.1, NM_028758.2 [Q6P5E6-1]

3D structure databases

SMRiQ6P5E6
ModBaseiSearch...

Protein-protein interaction databases

IntActiQ6P5E6, 3 interactors
MINTiQ6P5E6
STRINGi10090.ENSMUSP00000033160

PTM databases

iPTMnetiQ6P5E6
PhosphoSitePlusiQ6P5E6

Proteomic databases

EPDiQ6P5E6
PaxDbiQ6P5E6
PeptideAtlasiQ6P5E6
PRIDEiQ6P5E6
ProteomicsDBi267434 [Q6P5E6-1]
267435 [Q6P5E6-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
12586, 209 antibodies

The DNASU plasmid repository

More...
DNASUi
74105

Genome annotation databases

EnsembliENSMUST00000033160; ENSMUSP00000033160; ENSMUSG00000030872 [Q6P5E6-1]
ENSMUST00000124566; ENSMUSP00000115581; ENSMUSG00000030872 [Q6P5E6-1]
GeneIDi74105
KEGGimmu:74105
UCSCiuc009joa.1, mouse [Q6P5E6-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
23062
MGIiMGI:1921355, Gga2

Rodent Unidentified Gene-Encoded large proteins database

More...
Rougei
Search...

Phylogenomic databases

eggNOGiKOG1086, Eukaryota
GeneTreeiENSGT00940000159613
HOGENOMiCLU_015010_0_0_1
InParanoidiQ6P5E6
OMAiKVAGQNC
OrthoDBi594067at2759
PhylomeDBiQ6P5E6
TreeFamiTF318574

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
74105, 0 hits in 53 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Gga2, mouse

Protein Ontology

More...
PROi
PR:Q6P5E6
RNActiQ6P5E6, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000030872, Expressed in ear and 313 other tissues
GenevisibleiQ6P5E6, MM

Family and domain databases

Gene3Di1.20.58.160, 1 hit
1.25.40.90, 1 hit
InterProiView protein in InterPro
IPR008152, Clathrin_a/b/g-adaptin_app_Ig
IPR013041, Clathrin_app_Ig-like_sf
IPR008942, ENTH_VHS
IPR008153, GAE_dom
IPR004152, GAT_dom
IPR038425, GAT_sf
IPR041198, GGA_N-GAT
IPR002014, VHS_dom
PfamiView protein in Pfam
PF02883, Alpha_adaptinC2, 1 hit
PF03127, GAT, 1 hit
PF18308, GGA_N-GAT, 1 hit
PF00790, VHS, 1 hit
SMARTiView protein in SMART
SM00809, Alpha_adaptinC2, 1 hit
SM00288, VHS, 1 hit
SUPFAMiSSF48464, SSF48464, 1 hit
SSF49348, SSF49348, 1 hit
PROSITEiView protein in PROSITE
PS50180, GAE, 1 hit
PS50909, GAT, 1 hit
PS50179, VHS, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiGGA2_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6P5E6
Secondary accession number(s): Q3U374
, Q6PFX3, Q6ZPY8, Q8BM76, Q9DC15
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: July 5, 2004
Last modified: June 2, 2021
This is version 143 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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