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Protein
Submitted name:

Fragile X mental retardation syndrome-related protein 2

Gene

Fxr2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Fragile X mental retardation syndrome-related protein 2Imported
Submitted name:
Fragile X mental retardation, autosomal homolog 2Imported
Gene namesi
Name:Fxr2Imported
Synonyms:Fxr2hImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:1346074 Fxr2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000018765 Expressed in 254 organ(s), highest expression level in cerebellum

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini14 – 60Agenet-likeInterPro annotationAdd BLAST47
Domaini73 – 125Agenet-likeInterPro annotationAdd BLAST53

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili212 – 232Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410IF9J Eukaryota
ENOG410ZDJG LUCA
GeneTreeiENSGT00390000017033
HOGENOMiHOG000293377
HOVERGENiHBG005739
KOiK15516
OMAiHTTRTYG
OrthoDBiEOG091G08EZ
TreeFamiTF105427

Family and domain databases

Gene3Di3.30.1370.10, 2 hits
InterProiView protein in InterPro
IPR008395 Agenet-like_dom
IPR022034 FXMRP1_C_core
IPR032172 FXR_C1
IPR004087 KH_dom
IPR004088 KH_dom_type_1
IPR036612 KH_dom_type_1_sf
PfamiView protein in Pfam
PF05641 Agenet, 1 hit
PF12235 FXMRP1_C_core, 1 hit
PF16096 FXR_C1, 1 hit
PF00013 KH_1, 2 hits
SMARTiView protein in SMART
SM00322 KH, 2 hits
SUPFAMiSSF54791 SSF54791, 2 hits
PROSITEiView protein in PROSITE
PS51641 AGENET_LIKE, 2 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q6P5B5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGGLASGGDV EPGLPVEVRG SNGAFYKGFV KDVHEDSVTI FFENNWQSER
60 70 80 90 100
QIPFGDVRLP PPADYNKEIT EGDEVEVYSR ANEQEPCGWW LARVRMMKGD
110 120 130 140 150
FYVIEYAACD ATYNEIVTLE RLRPVNPSPL ATKGSFFKVT MAVPEDLREA
160 170 180 190 200
CSNENVHKEF KKALGANCIF LNITNSELFI LSTTEAPVKR ASLLGDMHFR
210 220 230 240 250
SLRTKLLLMS RNEEATKHLE TSKQLAAAFQ EEFTVREDLM GLAIGTHGAN
260 270 280 290 300
IQQARKVPGV TAIELGEETC TFRIYGETPE ACRQARSYLE FSEDSVQVPR
310 320 330 340 350
NLVGKVIGKN GKVIQEIVDK SGVVRVRVEG DNDKKNPREE GMVPFIFVGT
360 370 380 390 400
RENISNAQAL LEYHLSYLQE VEQLRLERLQ IDEQLRQIGL GFRPPGSGRG
410 420 430 440 450
GSGGGSDKAG YTTDESSSSS LHTTRTYGGS YGGRGRGRRT GGPAYGPSSD
460 470 480 490 500
PSTASETESE KREESNRAGP GDRDPPSRGE ESRRRPIGGR GRGPPPVPRP
510 520 530 540 550
TSRYNSSSIS SVLKDPDSNP YSLLDTSEPE PPVDSEPGEP PPASARRRRS
560 570 580 590 600
RRRRTDEDRT VMDGGLESDG PNMTENGLED ESRPQRRNRS RRRRNRGNRT
610 620 630 640 650
DGSISGDRQP VTVADYISRA ESQSRQRPLE RTKPSEDSLS GQKGDSVSKL
660 670
PKGPSENGEL SAPLELGSLV NGVS
Length:674
Mass (Da):74,253
Last modified:July 5, 2004 - v1
Checksum:i55ECC13AD09EFB34
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9WVR4FXR2_MOUSE
Fragile X mental retardation syndro...
Fxr2 Fxr2h
673Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL603707 Genomic DNA No translation available.
BC057007 mRNA Translation: AAH57007.1
BC062971 mRNA Translation: AAH62971.1
AK154243 mRNA Translation: BAE32459.1
RefSeqiNP_035944.2, NM_011814.2
UniGeneiMm.41930

Genome annotation databases

EnsembliENSMUST00000018909; ENSMUSP00000018909; ENSMUSG00000018765
GeneIDi23879
KEGGimmu:23879
UCSCiuc007jqt.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL603707 Genomic DNA No translation available.
BC057007 mRNA Translation: AAH57007.1
BC062971 mRNA Translation: AAH62971.1
AK154243 mRNA Translation: BAE32459.1
RefSeqiNP_035944.2, NM_011814.2
UniGeneiMm.41930

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000018909; ENSMUSP00000018909; ENSMUSG00000018765
GeneIDi23879
KEGGimmu:23879
UCSCiuc007jqt.1 mouse

Organism-specific databases

CTDi9513
MGIiMGI:1346074 Fxr2

Phylogenomic databases

eggNOGiENOG410IF9J Eukaryota
ENOG410ZDJG LUCA
GeneTreeiENSGT00390000017033
HOGENOMiHOG000293377
HOVERGENiHBG005739
KOiK15516
OMAiHTTRTYG
OrthoDBiEOG091G08EZ
TreeFamiTF105427

Miscellaneous databases

ChiTaRSiFxr2 mouse
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000018765 Expressed in 254 organ(s), highest expression level in cerebellum

Family and domain databases

Gene3Di3.30.1370.10, 2 hits
InterProiView protein in InterPro
IPR008395 Agenet-like_dom
IPR022034 FXMRP1_C_core
IPR032172 FXR_C1
IPR004087 KH_dom
IPR004088 KH_dom_type_1
IPR036612 KH_dom_type_1_sf
PfamiView protein in Pfam
PF05641 Agenet, 1 hit
PF12235 FXMRP1_C_core, 1 hit
PF16096 FXR_C1, 1 hit
PF00013 KH_1, 2 hits
SMARTiView protein in SMART
SM00322 KH, 2 hits
SUPFAMiSSF54791 SSF54791, 2 hits
PROSITEiView protein in PROSITE
PS51641 AGENET_LIKE, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiQ6P5B5_MOUSE
AccessioniPrimary (citable) accession number: Q6P5B5
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: September 12, 2018
This is version 128 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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