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Protein
Submitted name:

BCL2-associated X protein

Gene

bax

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-XTR-111457 Release of apoptotic factors from the mitochondria
R-XTR-114294 Activation, translocation and oligomerization of BAX
R-XTR-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest

Names & Taxonomyi

Protein namesi
Submitted name:
BCL2-associated X proteinImported
Gene namesi
Name:baxImported
ORF Names:TGas091l04.1-001Imported
OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)Imported
Taxonomic identifieri8364 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana
Proteomesi
  • UP000008143 Componenti: Unassembled WGS sequence

Organism-specific databases

XenbaseiXB-GENE-486067 bax

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei200 – 218HelicalSequence analysisAdd BLAST19

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSXETG00000023523

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi8364.ENSXETP00000050759

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IWQJ Eukaryota
ENOG4112738 LUCA
GeneTreeiENSGT00730000111112
HOGENOMiHOG000095178
HOVERGENiHBG003606
KOiK02159
OMAiVINWIRE
OrthoDBiEOG091G0YWR
TreeFamiTF315834

Family and domain databases

Gene3Di1.10.437.10, 1 hit
InterProiView protein in InterPro
IPR026304 BAX
IPR002475 Bcl2-like
IPR036834 Blc2-like_sf
IPR026298 Blc2_fam
PANTHERiPTHR11256 PTHR11256, 1 hit
PTHR11256:SF42 PTHR11256:SF42, 1 hit
PfamiView protein in Pfam
PF00452 Bcl-2, 1 hit
PRINTSiPR01862 BCL2FAMILY
SUPFAMiSSF56854 SSF56854, 1 hit
PROSITEiView protein in PROSITE
PS50062 BCL2_FAMILY, 1 hit

Sequencei

Sequence statusi: Complete.

Q6P4Y4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATHGAGGDY PGEDKEKNQG EGGAAGGPSL GAAGDRSGTG VSTEQILETG
60 70 80 90 100
ELLLNGFISD RLQNNPDVAG ARALFPGSTQ HSDPSIKRLS ECLRKIGDEL
110 120 130 140 150
DANIELQRRI ECVPCNSPKQ VFFHVAKELF ADGVFNWGRV VALFYFACKL
160 170 180 190 200
VVKALCTKVP EMIRTIINWT MEYLREYVVQ WIRDQGGWEG MLSYFGTPTW
210 220
QTVGVFLAGV LTATIAIWKM S
Length:221
Mass (Da):24,163
Last modified:July 5, 2004 - v1
Checksum:i87E367DB1614CEEB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAMC01122515 Genomic DNA No translation available.
BC063201 mRNA Translation: AAH63201.1
CR855728 mRNA Translation: CAJ81524.1
RefSeqiNP_989185.1, NM_203854.1
UniGeneiStr.6535

Genome annotation databases

EnsembliENSXETT00000050759; ENSXETP00000050759; ENSXETG00000023523
GeneIDi394793
KEGGixtr:394793

Similar proteinsi

Entry informationi

Entry nameiQ6P4Y4_XENTR
AccessioniPrimary (citable) accession number: Q6P4Y4
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: February 28, 2018
This is version 96 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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