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Entry version 117 (08 May 2019)
Sequence version 2 (07 Dec 2004)
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Protein

Mitochondrial fission regulator 2

Gene

MTFR2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May play a role in mitochondrial aerobic respiration essentially in the testis. Can also promote mitochondrial fission (By similarity).By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Mitochondrial fission regulator 2
Alternative name(s):
DUF729 domain-containing protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MTFR2
Synonyms:DUFD1, FAM54A
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:21115 MTFR2

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q6P444

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Mitochondrion

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000146410

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134871105

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
MTFR2

Domain mapping of disease mutations (DMDM)

More...
DMDMi
56404526

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedCombined sources
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000871642 – 385Mitochondrial fission regulator 2Add BLAST384

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylserineCombined sources1
Modified residuei119PhosphoserineCombined sources1
Modified residuei291PhosphoserineCombined sources1
Modified residuei328PhosphoserineCombined sources1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q6P444

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q6P444

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q6P444

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q6P444

PeptideAtlas

More...
PeptideAtlasi
Q6P444

PRoteomics IDEntifications database

More...
PRIDEi
Q6P444

ProteomicsDB human proteome resource

More...
ProteomicsDBi
66942
66943 [Q6P444-2]

PTM databases

CarbonylDB database of protein carbonylation sites

More...
CarbonylDBi
Q6P444

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q6P444

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q6P444

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000146410 Expressed in 126 organ(s), highest expression level in buccal mucosa cell

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q6P444 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q6P444 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA029792
HPA029794

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
125224, 18 interactors

Protein interaction database and analysis system

More...
IntActi
Q6P444, 10 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000395232

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q6P444

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi198 – 231Pro-richAdd BLAST34

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the MTFR1 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IIXQ Eukaryota
ENOG41122F0 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000183215

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q6P444

Identification of Orthologs from Complete Genome Data

More...
OMAi
PCRRPNF

Database of Orthologous Groups

More...
OrthoDBi
1485791at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q6P444

TreeFam database of animal gene trees

More...
TreeFami
TF331404

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR007972 Mtfr1

The PANTHER Classification System

More...
PANTHERi
PTHR14215 PTHR14215, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05308 Mito_fiss_reg, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q6P444-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSLILNILRE MLEYFGVPVE QVLLIWENKD YGSTRSIVRI IGKMLPLEPC
60 70 80 90 100
RRPNFELIPL LNSVDSDNCG SMVPSFADIL YVANDEEASY LRFRNSIWKN
110 120 130 140 150
EEEKVEIFHP LRLVRDPLSP AVRQKETVKN DLPVNEAAIR KIAALENELT
160 170 180 190 200
FLRSQIAAIV EMQELKNSTN SSSFGLSDER ISLGQLSSSR AAHLSVDPDQ
210 220 230 240 250
LPGSVLSPPP PPPLPPQFSS LQPPCFPPVQ PGSNNICDSD NPATEMSKQN
260 270 280 290 300
PAANKTNYSH HSKSQRNKDI PNMLDVLKDM NKVKLRAIER SPGGRPIHKR
310 320 330 340 350
KRQNSHWDPV SLISHALKQK FAFQEDDSFE KENRSWESSP FSSPETSRFG
360 370 380
HHISQSEGQR TKEEMVNTKA VDQGISNTSL LNSRI
Length:385
Mass (Da):43,384
Last modified:December 7, 2004 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i20A2970A9129CBB7
GO
Isoform 2 (identifier: Q6P444-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     22-44: VLLIWENKDYGSTRSIVRIIGKM → LEVTSAYLSSLWKKQTGRNLRST
     45-385: Missing.

Note: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. No experimental confirmation available.
Show »
Length:44
Mass (Da):5,116
Checksum:iB0223F0AFA6B2684
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9PN39E9PN39_HUMAN
Mitochondrial fission regulator 2
MTFR2
245Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YEA6H0YEA6_HUMAN
Mitochondrial fission regulator 2
MTFR2
115Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAC86277 differs from that shown. Reason: Erroneous translation. Wrong choice of CDS.Curated

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_03979522 – 44VLLIW…IIGKM → LEVTSAYLSSLWKKQTGRNL RST in isoform 2. 1 PublicationAdd BLAST23
Alternative sequenceiVSP_03979645 – 385Missing in isoform 2. 1 PublicationAdd BLAST341

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK125758 mRNA Translation: BAC86277.1 Sequence problems.
AK292303 mRNA Translation: BAF84992.1
AL121713 Genomic DNA No translation available.
AL138828 Genomic DNA No translation available.
CH471051 Genomic DNA Translation: EAW47953.1
CH471051 Genomic DNA Translation: EAW47954.1
BC011716 mRNA Translation: AAH11716.2
BC063688 mRNA Translation: AAH63688.2

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS5176.1 [Q6P444-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001092756.1, NM_001099286.2 [Q6P444-1]
NP_001305667.1, NM_001318738.1
NP_612428.2, NM_138419.4 [Q6P444-1]
XP_011533712.1, XM_011535410.2
XP_011533714.1, XM_011535412.2
XP_011533715.1, XM_011535413.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000367784; ENSP00000356758; ENSG00000146410 [Q6P444-2]
ENST00000420702; ENSP00000395232; ENSG00000146410 [Q6P444-1]
ENST00000451457; ENSP00000407010; ENSG00000146410 [Q6P444-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
113115

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:113115

UCSC genome browser

More...
UCSCi
uc003qgt.2 human [Q6P444-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK125758 mRNA Translation: BAC86277.1 Sequence problems.
AK292303 mRNA Translation: BAF84992.1
AL121713 Genomic DNA No translation available.
AL138828 Genomic DNA No translation available.
CH471051 Genomic DNA Translation: EAW47953.1
CH471051 Genomic DNA Translation: EAW47954.1
BC011716 mRNA Translation: AAH11716.2
BC063688 mRNA Translation: AAH63688.2
CCDSiCCDS5176.1 [Q6P444-1]
RefSeqiNP_001092756.1, NM_001099286.2 [Q6P444-1]
NP_001305667.1, NM_001318738.1
NP_612428.2, NM_138419.4 [Q6P444-1]
XP_011533712.1, XM_011535410.2
XP_011533714.1, XM_011535412.2
XP_011533715.1, XM_011535413.2

3D structure databases

SMRiQ6P444
ModBaseiSearch...

Protein-protein interaction databases

BioGridi125224, 18 interactors
IntActiQ6P444, 10 interactors
STRINGi9606.ENSP00000395232

PTM databases

CarbonylDBiQ6P444
iPTMnetiQ6P444
PhosphoSitePlusiQ6P444

Polymorphism and mutation databases

BioMutaiMTFR2
DMDMi56404526

Proteomic databases

EPDiQ6P444
jPOSTiQ6P444
MaxQBiQ6P444
PaxDbiQ6P444
PeptideAtlasiQ6P444
PRIDEiQ6P444
ProteomicsDBi66942
66943 [Q6P444-2]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
113115
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000367784; ENSP00000356758; ENSG00000146410 [Q6P444-2]
ENST00000420702; ENSP00000395232; ENSG00000146410 [Q6P444-1]
ENST00000451457; ENSP00000407010; ENSG00000146410 [Q6P444-1]
GeneIDi113115
KEGGihsa:113115
UCSCiuc003qgt.2 human [Q6P444-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
113115

GeneCards: human genes, protein and diseases

More...
GeneCardsi
MTFR2
HGNCiHGNC:21115 MTFR2
HPAiHPA029792
HPA029794
neXtProtiNX_Q6P444
OpenTargetsiENSG00000146410
PharmGKBiPA134871105

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IIXQ Eukaryota
ENOG41122F0 LUCA
GeneTreeiENSGT00950000183215
InParanoidiQ6P444
OMAiPCRRPNF
OrthoDBi1485791at2759
PhylomeDBiQ6P444
TreeFamiTF331404

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
113115

Protein Ontology

More...
PROi
PR:Q6P444

Gene expression databases

BgeeiENSG00000146410 Expressed in 126 organ(s), highest expression level in buccal mucosa cell
ExpressionAtlasiQ6P444 baseline and differential
GenevisibleiQ6P444 HS

Family and domain databases

InterProiView protein in InterPro
IPR007972 Mtfr1
PANTHERiPTHR14215 PTHR14215, 1 hit
PfamiView protein in Pfam
PF05308 Mito_fiss_reg, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMTFR2_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6P444
Secondary accession number(s): A8K8D8
, E1P585, Q5JWR7, Q6ZUE8, Q7L3U6, Q9BZ39
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 7, 2004
Last sequence update: December 7, 2004
Last modified: May 8, 2019
This is version 117 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
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