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Protein

PiggyBac transposable element-derived protein 2

Gene

PGBD2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
PiggyBac transposable element-derived protein 2
Gene namesi
Name:PGBD2
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000185220.11
HGNCiHGNC:19399 PGBD2
neXtProtiNX_Q6P3X8

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000185220
PharmGKBiPA134877743

Polymorphism and mutation databases

BioMutaiPGBD2
DMDMi74749095

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002880531 – 592PiggyBac transposable element-derived protein 2Add BLAST592

Proteomic databases

MaxQBiQ6P3X8
PaxDbiQ6P3X8
PeptideAtlasiQ6P3X8
PRIDEiQ6P3X8
ProteomicsDBi66939
66940 [Q6P3X8-2]

PTM databases

iPTMnetiQ6P3X8
PhosphoSitePlusiQ6P3X8

Expressioni

Gene expression databases

BgeeiENSG00000185220 Expressed in 175 organ(s), highest expression level in testis
CleanExiHS_PGBD2
ExpressionAtlasiQ6P3X8 baseline and differential
GenevisibleiQ6P3X8 HS

Organism-specific databases

HPAiHPA029888
HPA029889
HPA029890

Interactioni

Protein-protein interaction databases

BioGridi129355, 1 interactor
STRINGi9606.ENSP00000331643

Structurei

3D structure databases

ProteinModelPortaliQ6P3X8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410IHMN Eukaryota
ENOG410ZDPG LUCA
GeneTreeiENSGT00530000063278
HOGENOMiHOG000065760
HOVERGENiHBG059393
InParanoidiQ6P3X8
OMAiRTRCALC
OrthoDBiEOG091G05IL
PhylomeDBiQ6P3X8
TreeFamiTF328011

Family and domain databases

InterProiView protein in InterPro
IPR029526 PGBD
PfamiView protein in Pfam
PF13843 DDE_Tnp_1_7, 1 hit

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q6P3X8-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MASTSRDVIA GRGIHSKVKS AKLLEVLNAM EEEESNNNRE EIFIAPPDNA
60 70 80 90 100
AGEFTDEDSG DEDSQRGAHL PGSVLHASVL CEDSGTGEDN DDLELQPAKK
110 120 130 140 150
RQKAVVKPQR IWTKRDIRPD FGSWTASDPH IEDLKSQELS PVGLFELFFD
160 170 180 190 200
EGTINFIVNE TNRYAWQKNV NLSLTAQELK CVLGILILSG YISYPRRRMF
210 220 230 240 250
WETSPDSHHH LVADAIRRDR FELIFSYLHF ADNNELDASD RFAKVRPLII
260 270 280 290 300
RMNCNFQKHA PLEEFYSFGE SMCEYFGHRG SKQLHRGKPV RLGYKIWCGT
310 320 330 340 350
TSRGYLVWFE PSQGTLFTKP DRSLDLGGSM VIKFVDALQE RGFLPYHIFF
360 370 380 390 400
DKVFTSVKLM SILRKKGVKA TGTVREYRTE RCPLKDPKEL KKMKRGSFDY
410 420 430 440 450
KVDESEEIIV CRWHDSSVVN ICSNAVGIEP VRLTSRHSGA AKTRTQVHQP
460 470 480 490 500
SLVKLYQEKV GGVGRMDQNI AKYKVKIRGM KWYSSFIGYV IDAALNNAWQ
510 520 530 540 550
LHRICCQDAQ VDLLAFRRYI ACVYLESNAD TTSQGRRSRR LETESRFDMI
560 570 580 590
GHWIIHQDKR TRCALCHSQT NTRCEKCQKG VHAKCFREYH IR
Length:592
Mass (Da):68,011
Last modified:July 5, 2004 - v1
Checksum:i59B8B2AEB823963D
GO
Isoform 2 (identifier: Q6P3X8-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-251: Missing.

Show »
Length:341
Mass (Da):39,563
Checksum:i5AED31C4AD569B2E
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0256311 – 251Missing in isoform 2. 2 PublicationsAdd BLAST251

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK123219 mRNA Translation: BAG53880.1
BX647065 mRNA Translation: CAE46192.1
AL672183 Genomic DNA No translation available.
CH471257 Genomic DNA Translation: EAW57544.1
BC063785 mRNA Translation: AAH63785.1
CCDSiCCDS31128.1 [Q6P3X8-1]
CCDS31129.1 [Q6P3X8-2]
RefSeqiNP_001017434.1, NM_001017434.1 [Q6P3X8-2]
NP_733843.1, NM_170725.2 [Q6P3X8-1]
XP_011542461.1, XM_011544159.2 [Q6P3X8-1]
XP_011542463.1, XM_011544161.2 [Q6P3X8-1]
UniGeneiHs.602037

Genome annotation databases

EnsembliENST00000329291; ENSP00000331643; ENSG00000185220 [Q6P3X8-1]
ENST00000355360; ENSP00000355424; ENSG00000185220 [Q6P3X8-2]
GeneIDi267002
KEGGihsa:267002
UCSCiuc001ifg.4 human [Q6P3X8-1]

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Entry informationi

Entry nameiPGBD2_HUMAN
AccessioniPrimary (citable) accession number: Q6P3X8
Secondary accession number(s): B3KVR8, Q6MZF8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: July 5, 2004
Last modified: September 12, 2018
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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