Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

F-box only protein 42

Gene

FBXO42

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Specifically recognizes p53/TP53, promoting its ubiquitination and degradation.1 Publication

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processUbl conjugation pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
F-box only protein 42
Alternative name(s):
Just one F-box and Kelch domain-containing protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:FBXO42
Synonyms:FBX42, JFK, KIAA1332
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000037637.10

Human Gene Nomenclature Database

More...
HGNCi
HGNC:29249 FBXO42

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
609109 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q6P3S6

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000037637

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134951560

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
FBXO42

Domain mapping of disease mutations (DMDM)

More...
DMDMi
51701398

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001199421 – 717F-box only protein 42Add BLAST717

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei365PhosphoserineCombined sources1
Modified residuei373PhosphoserineCombined sources1
Modified residuei378PhosphothreonineCombined sources1
Modified residuei552PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q6P3S6

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q6P3S6

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q6P3S6

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q6P3S6

PeptideAtlas

More...
PeptideAtlasi
Q6P3S6

PRoteomics IDEntifications database

More...
PRIDEi
Q6P3S6

ProteomicsDB human proteome resource

More...
ProteomicsDBi
66931

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q6P3S6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q6P3S6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000037637 Expressed in 230 organ(s), highest expression level in saliva-secreting gland

CleanEx database of gene expression profiles

More...
CleanExi
HS_FBXO42

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q6P3S6 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q6P3S6 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA025071

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of some SCF complex, composed of CUL1, SKP1, RBX1 and FBXO42. Interacts (via the kelch domain) with p53/TP53; interaction is direct.1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
RBPJQ063303EBI-2506081,EBI-632552

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
119962, 15 interactors

Protein interaction database and analysis system

More...
IntActi
Q6P3S6, 3 interactors

Molecular INTeraction database

More...
MINTi
Q6P3S6

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000364742

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q6P3S6

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini44 – 93F-boxPROSITE-ProRule annotationAdd BLAST50
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati132 – 184Kelch 1Add BLAST53
Repeati186 – 242Kelch 2Add BLAST57
Repeati244 – 293Kelch 3Add BLAST50
Repeati295 – 342Kelch 4Add BLAST48

Keywords - Domaini

Kelch repeat, Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0379 Eukaryota
ENOG410Y5WM LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00440000039706

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG051582

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q6P3S6

KEGG Orthology (KO)

More...
KOi
K10317

Identification of Orthologs from Complete Genome Data

More...
OMAi
IDLNWDL

Database of Orthologous Groups

More...
OrthoDBi
838833at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q6P3S6

TreeFam database of animal gene trees

More...
TreeFami
TF324505

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.120.10.80, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036047 F-box-like_dom_sf
IPR001810 F-box_dom
IPR015915 Kelch-typ_b-propeller
IPR011498 Kelch_2

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12937 F-box-like, 1 hit
PF07646 Kelch_2, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00256 FBOX, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF117281 SSF117281, 1 hit
SSF81383 SSF81383, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50181 FBOX, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q6P3S6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASSSDSEDD SFMAVDQEET VLEGTMDQDE EPHPVLEAEE TRHNRSMSEL
60 70 80 90 100
PEEVLEYILS FLSPYQEHKT AALVCKQWYR LIKGVAHQCY HGFMKAVQEG
110 120 130 140 150
NIQWESRTYP YPGTPITQRF SHSACYYDAN QSMYVFGGCT QSSCNAAFND
160 170 180 190 200
LWRLDLNSKE WIRPLASGSY PSPKAGATLV VYKDLLVLFG GWTRPSPYPL
210 220 230 240 250
HQPERFFDEI HTYSPSKNWW NCIVTTHGPP PMAGHSSCVI DDKMIVFGGS
260 270 280 290 300
LGSRQMSNDV WVLDLEQWAW SKPNISGPSP HPRGGQSQIV IDDATILILG
310 320 330 340 350
GCGGPNALFK DAWLLHMHSG PWAWQPLKVE NEEHGAPELW CHPACRVGQC
360 370 380 390 400
VVVFSQAPSG RAPLSPSLNS RPSPISATPP ALVPETREYR SQSPVRSMDE
410 420 430 440 450
APCVNGRWGT LRPRAQRQTP SGSREGSLSP ARGDGSPILN GGSLSPGTAA
460 470 480 490 500
VGGSSLDSPV QAISPSTPSA PEGYDLKIGL SLAPRRGSLP DQKDLRLGSI
510 520 530 540 550
DLNWDLKPAS SSNPMDGMDN RTVGGSMRHP PEQTNGVHTP PHVASALAGA
560 570 580 590 600
VSPGALRRSL EAIKAMSSKG PSASAALSPP LGSSPGSPGS QSLSSGETVP
610 620 630 640 650
IPRPGPAQGD GHSLPPIARR LGHHPPQSLN VGKPLYQSMN CKPMQMYVLD
660 670 680 690 700
IKDTKEKGRV KWKVFNSSSV VGPPETSLHT VVQGRGELII FGGLMDKKQN
710
VKYYPKTNAL YFVRAKR
Length:717
Mass (Da):77,839
Last modified:July 5, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i938D0A018FC3DCBD
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
X6RKU3X6RKU3_HUMAN
F-box only protein 42
FBXO42
298Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti454Missing in AAH43410 (PubMed:15489334).Curated1
Sequence conflicti509A → T in CAD38731 (PubMed:17974005).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_024447471P → A3 PublicationsCorresponds to variant dbSNP:rs12069239Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK055598 mRNA Translation: BAG51542.1
AL109627 Genomic DNA No translation available.
AL358794 Genomic DNA No translation available.
BC006174 mRNA Translation: AAH06174.1
BC032439 mRNA Translation: AAH32439.1
BC043410 mRNA Translation: AAH43410.1
BC063864 mRNA Translation: AAH63864.1
AB037753 mRNA Translation: BAA92570.1
AL833874 mRNA Translation: CAD38731.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS30613.1

NCBI Reference Sequences

More...
RefSeqi
NP_061867.1, NM_018994.2
XP_006710761.1, XM_006710698.3

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.522384

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000375592; ENSP00000364742; ENSG00000037637

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
54455

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:54455

UCSC genome browser

More...
UCSCi
uc001ayg.4 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK055598 mRNA Translation: BAG51542.1
AL109627 Genomic DNA No translation available.
AL358794 Genomic DNA No translation available.
BC006174 mRNA Translation: AAH06174.1
BC032439 mRNA Translation: AAH32439.1
BC043410 mRNA Translation: AAH43410.1
BC063864 mRNA Translation: AAH63864.1
AB037753 mRNA Translation: BAA92570.1
AL833874 mRNA Translation: CAD38731.1
CCDSiCCDS30613.1
RefSeqiNP_061867.1, NM_018994.2
XP_006710761.1, XM_006710698.3
UniGeneiHs.522384

3D structure databases

ProteinModelPortaliQ6P3S6
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi119962, 15 interactors
IntActiQ6P3S6, 3 interactors
MINTiQ6P3S6
STRINGi9606.ENSP00000364742

PTM databases

iPTMnetiQ6P3S6
PhosphoSitePlusiQ6P3S6

Polymorphism and mutation databases

BioMutaiFBXO42
DMDMi51701398

Proteomic databases

EPDiQ6P3S6
jPOSTiQ6P3S6
MaxQBiQ6P3S6
PaxDbiQ6P3S6
PeptideAtlasiQ6P3S6
PRIDEiQ6P3S6
ProteomicsDBi66931

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000375592; ENSP00000364742; ENSG00000037637
GeneIDi54455
KEGGihsa:54455
UCSCiuc001ayg.4 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
54455
EuPathDBiHostDB:ENSG00000037637.10

GeneCards: human genes, protein and diseases

More...
GeneCardsi
FBXO42
HGNCiHGNC:29249 FBXO42
HPAiHPA025071
MIMi609109 gene
neXtProtiNX_Q6P3S6
OpenTargetsiENSG00000037637
PharmGKBiPA134951560

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG0379 Eukaryota
ENOG410Y5WM LUCA
GeneTreeiENSGT00440000039706
HOVERGENiHBG051582
InParanoidiQ6P3S6
KOiK10317
OMAiIDLNWDL
OrthoDBi838833at2759
PhylomeDBiQ6P3S6
TreeFamiTF324505

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
FBXO42 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
54455

Protein Ontology

More...
PROi
PR:Q6P3S6

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000037637 Expressed in 230 organ(s), highest expression level in saliva-secreting gland
CleanExiHS_FBXO42
ExpressionAtlasiQ6P3S6 baseline and differential
GenevisibleiQ6P3S6 HS

Family and domain databases

Gene3Di2.120.10.80, 1 hit
InterProiView protein in InterPro
IPR036047 F-box-like_dom_sf
IPR001810 F-box_dom
IPR015915 Kelch-typ_b-propeller
IPR011498 Kelch_2
PfamiView protein in Pfam
PF12937 F-box-like, 1 hit
PF07646 Kelch_2, 1 hit
SMARTiView protein in SMART
SM00256 FBOX, 1 hit
SUPFAMiSSF117281 SSF117281, 1 hit
SSF81383 SSF81383, 1 hit
PROSITEiView protein in PROSITE
PS50181 FBOX, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiFBX42_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6P3S6
Secondary accession number(s): B3KP30
, Q5TEU8, Q86XI0, Q8N3N4, Q8N5F8, Q9BRM0, Q9P2L4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 31, 2004
Last sequence update: July 5, 2004
Last modified: January 16, 2019
This is version 129 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again