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UniProtKB - Q6P3A9 (ARL11_MOUSE)
Protein
ADP-ribosylation factor-like protein 11
Gene
Arl11
Organism
Mus musculus (Mouse)
Status
Functioni
May play a role in apoptosis. May act as a tumor suppressor (By similarity).
By similarityRegions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 19 – 26 | GTPBy similarity | 8 | |
Nucleotide bindingi | 63 – 67 | GTPBy similarity | 5 | |
Nucleotide bindingi | 122 – 125 | GTPBy similarity | 4 |
GO - Molecular functioni
- GTPase activity Source: InterPro
- GTP binding Source: GO_Central
GO - Biological processi
- hematopoietic progenitor cell differentiation Source: MGI
- intracellular protein transport Source: GO_Central
- vesicle-mediated transport Source: GO_Central
Keywordsi
Ligand | GTP-binding, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Recommended name: ADP-ribosylation factor-like protein 11 |
Gene namesi | Name:Arl11 |
Organismi | Mus musculus (Mouse) |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:2444054, Arl11 |
VEuPathDBi | HostDB:ENSMUSG00000043157 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Initiator methioninei | RemovedSequence analysis | |||
ChainiPRO_0000207480 | 2 – 176 | ADP-ribosylation factor-like protein 11Add BLAST | 175 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Lipidationi | 2 | N-myristoyl glycineSequence analysis | 1 |
Keywords - PTMi
Lipoprotein, MyristateProteomic databases
MaxQBi | Q6P3A9 |
PaxDbi | Q6P3A9 |
PRIDEi | Q6P3A9 |
ProteomicsDBi | 265101 |
PTM databases
iPTMneti | Q6P3A9 |
PhosphoSitePlusi | Q6P3A9 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000043157, Expressed in granulocyte and 71 other tissues |
Interactioni
Protein-protein interaction databases
STRINGi | 10090.ENSMUSP00000055447 |
Miscellaneous databases
RNActi | Q6P3A9, protein |
Family & Domainsi
Sequence similaritiesi
Phylogenomic databases
eggNOGi | KOG0070, Eukaryota |
GeneTreei | ENSGT00940000162731 |
HOGENOMi | CLU_040729_9_2_1 |
InParanoidi | Q6P3A9 |
OMAi | WRKRDAR |
OrthoDBi | 1271528at2759 |
PhylomeDBi | Q6P3A9 |
TreeFami | TF105471 |
Family and domain databases
Gene3Di | 3.40.50.300, 1 hit |
InterProi | View protein in InterPro IPR027417, P-loop_NTPase IPR005225, Small_GTP-bd_dom IPR024156, Small_GTPase_ARF IPR006689, Small_GTPase_ARF/SAR |
PANTHERi | PTHR11711, PTHR11711, 1 hit |
Pfami | View protein in Pfam PF00025, Arf, 1 hit |
PRINTSi | PR00328, SAR1GTPBP |
SMARTi | View protein in SMART SM00178, SAR, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
TIGRFAMsi | TIGR00231, small_GTP, 1 hit |
PROSITEi | View protein in PROSITE PS51417, ARF, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
Q6P3A9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGSVNSRGHK AEAQVVMMGL DSAGKTTILY KLKGNQLVDT LPTVGFNVEP
60 70 80 90 100
LEAPGHVSLT LWDIGGQTQL RATWKDYLEG IDLLVYVLDS TDEARLPEAV
110 120 130 140 150
AELKEVLEDP NMAGVPFLVL ANKQEAPGAL PLLEIRNRLG LEGFQKHCWE
160 170
LRACSALTGQ GLQEALQSLL HLLKSR
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 60 | T → S in BAC34053 (PubMed:16141072).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK008804 mRNA Translation: BAE43212.1 AK050053 mRNA Translation: BAC34053.1 BC064093 mRNA Translation: AAH64093.1 |
CCDSi | CCDS27182.1 |
RefSeqi | NP_796311.2, NM_177337.3 XP_011243330.1, XM_011245028.1 |
Genome annotation databases
Ensembli | ENSMUST00000055159; ENSMUSP00000055447; ENSMUSG00000043157 ENSMUST00000224727; ENSMUSP00000153531; ENSMUSG00000043157 |
GeneIDi | 219144 |
KEGGi | mmu:219144 |
UCSCi | uc007ufu.1, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK008804 mRNA Translation: BAE43212.1 AK050053 mRNA Translation: BAC34053.1 BC064093 mRNA Translation: AAH64093.1 |
CCDSi | CCDS27182.1 |
RefSeqi | NP_796311.2, NM_177337.3 XP_011243330.1, XM_011245028.1 |
3D structure databases
SMRi | Q6P3A9 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 10090.ENSMUSP00000055447 |
PTM databases
iPTMneti | Q6P3A9 |
PhosphoSitePlusi | Q6P3A9 |
Proteomic databases
MaxQBi | Q6P3A9 |
PaxDbi | Q6P3A9 |
PRIDEi | Q6P3A9 |
ProteomicsDBi | 265101 |
Protocols and materials databases
Antibodypediai | 23950, 205 antibodies from 24 providers |
DNASUi | 219144 |
Genome annotation databases
Ensembli | ENSMUST00000055159; ENSMUSP00000055447; ENSMUSG00000043157 ENSMUST00000224727; ENSMUSP00000153531; ENSMUSG00000043157 |
GeneIDi | 219144 |
KEGGi | mmu:219144 |
UCSCi | uc007ufu.1, mouse |
Organism-specific databases
CTDi | 115761 |
MGIi | MGI:2444054, Arl11 |
VEuPathDBi | HostDB:ENSMUSG00000043157 |
Phylogenomic databases
eggNOGi | KOG0070, Eukaryota |
GeneTreei | ENSGT00940000162731 |
HOGENOMi | CLU_040729_9_2_1 |
InParanoidi | Q6P3A9 |
OMAi | WRKRDAR |
OrthoDBi | 1271528at2759 |
PhylomeDBi | Q6P3A9 |
TreeFami | TF105471 |
Miscellaneous databases
BioGRID-ORCSi | 219144, 1 hit in 63 CRISPR screens |
ChiTaRSi | Arl11, mouse |
PROi | PR:Q6P3A9 |
RNActi | Q6P3A9, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000043157, Expressed in granulocyte and 71 other tissues |
Family and domain databases
Gene3Di | 3.40.50.300, 1 hit |
InterProi | View protein in InterPro IPR027417, P-loop_NTPase IPR005225, Small_GTP-bd_dom IPR024156, Small_GTPase_ARF IPR006689, Small_GTPase_ARF/SAR |
PANTHERi | PTHR11711, PTHR11711, 1 hit |
Pfami | View protein in Pfam PF00025, Arf, 1 hit |
PRINTSi | PR00328, SAR1GTPBP |
SMARTi | View protein in SMART SM00178, SAR, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
TIGRFAMsi | TIGR00231, small_GTP, 1 hit |
PROSITEi | View protein in PROSITE PS51417, ARF, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | ARL11_MOUSE | |
Accessioni | Q6P3A9Primary (citable) accession number: Q6P3A9 Secondary accession number(s): Q8C7K1 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 8, 2005 |
Last sequence update: | July 5, 2004 | |
Last modified: | February 23, 2022 | |
This is version 138 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot - SIMILARITY comments
Index of protein domains and families