Arl11

Functionⁱ

May play a role in apoptosis. May act as a tumor suppressor (By similarity).By similarity

Regions

Feature key	Position(s)	DescriptionActions	Length
Nucleotide bindingⁱ	19 – 26	GTPBy similarity	8
Nucleotide bindingⁱ	63 – 67	GTPBy similarity	5
Nucleotide bindingⁱ	122 – 125	GTPBy similarity	4

GO - Molecular functionⁱ

GTP binding
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

hematopoietic progenitor cell differentiation
Source: MGI
Inferred from mutant phenotypeⁱ
- 24029230
intracellular protein transport
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
vesicle-mediated transport
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Ligand	GTP-binding, Nucleotide-binding

Ligand

GTP-binding, Nucleotide-binding

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: ADP-ribosylation factor-like protein 11
Gene namesⁱ	Name:Arl11
Organismⁱ	Mus musculus (Mouse)
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome 14

Organism-specific databases

MGIⁱ	MGI:2444054 Arl11

Subcellular locationⁱ

GO - Cellular component

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Initiator methionineⁱ		RemovedSequence analysis
ChainⁱPRO_0000207480	2 – 176	ADP-ribosylation factor-like protein 11Add BLAST		175

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Lipidationⁱ	2	N-myristoyl glycineSequence analysis		1

Keywords - PTMⁱ

Lipoprotein, Myristate

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q6P3A9
PaxDbⁱ	Q6P3A9
PRIDEⁱ	Q6P3A9

PTM databases

iPTMnetⁱ	Q6P3A9
PhosphoSitePlusⁱ	Q6P3A9

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSMUSG00000043157 Expressed in 24 organ(s), highest expression level in bone marrow macrophage
CleanExⁱ	MM_ARL11

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	10090.ENSMUSP00000055447

STRINGⁱ

10090.ENSMUSP00000055447

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q6P3A9
SMRⁱ	Q6P3A9
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the small GTPase superfamily. Arf family.Curated

Phylogenomic databases

eggNOGⁱ	KOG0070 Eukaryota COG1100 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00930000150892
HOGENOMⁱ	HOG000163691
HOVERGENⁱ	HBG002073
InParanoidⁱ	Q6P3A9
KEGG Orthology (KO) More...KOⁱ	K07959
OMAⁱ	WELRACS
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0O0X
PhylomeDBⁱ	Q6P3A9
TreeFamⁱ	TF105471

Family and domain databases

InterProⁱ	View protein in InterPro IPR027417 P-loop_NTPase IPR005225 Small_GTP-bd_dom IPR006689 Small_GTPase_ARF/SAR
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00025 Arf, 1 hit
PRINTSⁱ	PR00328 SAR1GTPBP
SUPFAMⁱ	SSF52540 SSF52540, 1 hit
TIGRFAMsⁱ	TIGR00231 small_GTP, 1 hit
PROSITEⁱ	View protein in PROSITE PS51417 ARF, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

Sequence processingⁱ: The displayed sequence is further processed into a mature form.

Q6P3A9-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MGSVNSRGHK AEAQVVMMGL DSAGKTTILY KLKGNQLVDT LPTVGFNVEP 
        60         70         80         90        100
LEAPGHVSLT LWDIGGQTQL RATWKDYLEG IDLLVYVLDS TDEARLPEAV 
       110        120        130        140        150
AELKEVLEDP NMAGVPFLVL ANKQEAPGAL PLLEIRNRLG LEGFQKHCWE 
       160        170 
LRACSALTGQ GLQEALQSLL HLLKSR

Length:176

Mass (Da):19,212

Last modified:July 5, 2004 - v1

Checksum:ⁱ11D8E6C970E81C60

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	60	T → S in BAC34053 (PubMed:16141072).Curated		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK008804 mRNA Translation: BAE43212.1 AK050053 mRNA Translation: BAC34053.1 BC064093 mRNA Translation: AAH64093.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS27182.1
NCBI Reference Sequences More...RefSeqⁱ	NP_796311.2, NM_177337.3 XP_011243330.1, XM_011245028.1
UniGeneⁱ	Mm.206566

Genome annotation databases

Ensemblⁱ	ENSMUST00000055159; ENSMUSP00000055447; ENSMUSG00000043157 ENSMUST00000224727; ENSMUSP00000153531; ENSMUSG00000043157
GeneIDⁱ	219144
KEGGⁱ	mmu:219144
UCSC genome browser More...UCSCⁱ	uc007ufu.1 mouse

Protein	Similar proteins		Species	Score	Length	Source
Q6P3A9	ADP-ribosylation factor-like protein 11		RAT		173	UniRef90_Q6P3A9
ADP-ribosylation factor-like protein 11		CRIGR		176
UPI00038C3AC6		MICOH		176
UPI00042ADE74		PERMB		176
UPI000A3084F4		MUSPA		176
+4

Protein	Similar proteins		Species	Score	Length	Source
Q6P3A9	ADP-ribosylation factor-like protein 11		HUMAN		196	UniRef50_Q969Q4
ADP-ribosylation factor-like protein 11		RAT		173
ADP-ribosylation factor-like protein 11		BOVIN		182
ADP-ribosylation factor-like protein 11		MACMU		196
ADP-ribosylation factor-like tumor suppressor protein 1		MACFA		196
+129

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK008804 mRNA Translation: BAE43212.1 AK050053 mRNA Translation: BAC34053.1 BC064093 mRNA Translation: AAH64093.1
CCDSⁱ	CCDS27182.1
RefSeqⁱ	NP_796311.2, NM_177337.3 XP_011243330.1, XM_011245028.1
UniGeneⁱ	Mm.206566

3D structure databases

ProteinModelPortalⁱ	Q6P3A9
SMRⁱ	Q6P3A9
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	10090.ENSMUSP00000055447

STRINGⁱ

10090.ENSMUSP00000055447

PTM databases

iPTMnetⁱ	Q6P3A9
PhosphoSitePlusⁱ	Q6P3A9

Proteomic databases

MaxQBⁱ	Q6P3A9
PaxDbⁱ	Q6P3A9
PRIDEⁱ	Q6P3A9

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000055159; ENSMUSP00000055447; ENSMUSG00000043157 ENSMUST00000224727; ENSMUSP00000153531; ENSMUSG00000043157
GeneIDⁱ	219144
KEGGⁱ	mmu:219144
UCSCⁱ	uc007ufu.1 mouse

Organism-specific databases

CTDⁱ	115761
MGIⁱ	MGI:2444054 Arl11

Phylogenomic databases

eggNOGⁱ	KOG0070 Eukaryota COG1100 LUCA
GeneTreeⁱ	ENSGT00930000150892
HOGENOMⁱ	HOG000163691
HOVERGENⁱ	HBG002073
InParanoidⁱ	Q6P3A9
KOⁱ	K07959
OMAⁱ	WELRACS
OrthoDBⁱ	EOG091G0O0X
PhylomeDBⁱ	Q6P3A9
TreeFamⁱ	TF105471

Miscellaneous databases

ChiTaRSⁱ	Arl11 mouse
Protein Ontology More...PROⁱ	PR:Q6P3A9
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000043157 Expressed in 24 organ(s), highest expression level in bone marrow macrophage
CleanExⁱ	MM_ARL11

Family and domain databases

InterProⁱ	View protein in InterPro IPR027417 P-loop_NTPase IPR005225 Small_GTP-bd_dom IPR006689 Small_GTPase_ARF/SAR
Pfamⁱ	View protein in Pfam PF00025 Arf, 1 hit
PRINTSⁱ	PR00328 SAR1GTPBP
SUPFAMⁱ	SSF52540 SSF52540, 1 hit
TIGRFAMsⁱ	TIGR00231 small_GTP, 1 hit
PROSITEⁱ	View protein in PROSITE PS51417 ARF, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	ARL11_MOUSE
Accessionⁱ	Q6P3A9Primary (citable) accession number: Q6P3A9 Secondary accession number(s): Q8C7K1
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	November 8, 2005
	Last sequence update:	July 5, 2004
	Last modified:	November 7, 2018
	This is version 123 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q6P3A9 (ARL11_MOUSE)

Your basket is currently empty. i <p>When browsing through different UniProt proteins, you can use the ‘basket’ to save them, so that you can back to find or analyse them later.<p><a href='/help/basket' target='_top'>More...</a></p>

ADP-ribosylation factor-like protein 11

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Plasma Membrane

Other locations

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

UniProt is an ELIXIR core data resource

Your basket is currently empty. ⁱ

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ