UniProtKB - Q6P2S7 (TTC41_HUMAN)
Protein
Putative tetratricopeptide repeat protein 41
Gene
TTC41P
Organism
Homo sapiens (Human)
Status
Functioni
Caution
Could be the product of a pseudogene.Curated
Enzyme and pathway databases
PathwayCommonsi | Q6P2S7 |
Names & Taxonomyi
Protein namesi | Recommended name: Putative tetratricopeptide repeat protein 41By similarityShort name: TPR repeat protein 41By similarity Alternative name(s): Grp94-neighboring nucleotidaseBy similarity |
Gene namesi | |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:49210, TTC41P |
neXtProti | NX_Q6P2S7 |
Subcellular locationi
Keywords - Cellular componenti
CytoplasmPathology & Biotechi
Miscellaneous databases
Pharosi | Q6P2S7, Tdark |
Genetic variation databases
BioMutai | HGNC:49210 |
DMDMi | 193806376 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000325940 | 1 – 1318 | Putative tetratricopeptide repeat protein 41Add BLAST | 1318 |
Proteomic databases
EPDi | Q6P2S7 |
MassIVEi | Q6P2S7 |
PRIDEi | Q6P2S7 |
ProteomicsDBi | 66919 [Q6P2S7-1] 66920 [Q6P2S7-2] 66921 [Q6P2S7-3] |
PTM databases
iPTMneti | Q6P2S7 |
PhosphoSitePlusi | Q6P2S7 |
Interactioni
Protein-protein interaction databases
IntActi | Q6P2S7, 1 interactor |
Miscellaneous databases
RNActi | Q6P2S7, protein |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 399 – 432 | TPR 1Add BLAST | 34 | |
Repeati | 653 – 684 | TPR 2Add BLAST | 32 | |
Repeati | 817 – 850 | TPR 3Add BLAST | 34 | |
Repeati | 858 – 891 | TPR 4Add BLAST | 34 | |
Repeati | 991 – 1027 | TPR 5Add BLAST | 37 | |
Repeati | 1045 – 1082 | TPR 6Add BLAST | 38 |
Keywords - Domaini
Repeat, TPR repeatPhylogenomic databases
InParanoidi | Q6P2S7 |
PhylomeDBi | Q6P2S7 |
Family and domain databases
Gene3Di | 1.25.40.10, 1 hit |
InterProi | View protein in InterPro IPR027417, P-loop_NTPase IPR011990, TPR-like_helical_dom_sf |
SUPFAMi | SSF52540, SSF52540, 1 hit |
s (3)i Sequence
Sequence statusi: Complete.
This entry describes 3 produced by isoformsialternative splicing. AlignAdd to basketIsoform 1 (identifier: Q6P2S7-1) [UniParc]FASTAAdd to basket
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MSQKTNENVE RYTQFLQKPQ KPIQPYICST LNDFQEERDF LANNIFPQLN
60 70 80 90 100
ELCNSWGTYF KAVDLSWSAL KAPKSLPTHL FRQYSCLRSQ RLKLCLDYVN
110 120 130 140 150
SCFPFFICML GQTYGDFLPD YSHFMTSKVT RLSSLSKVEN LYVAAKNGYP
160 170 180 190 200
WVLENPSCSL TEFEIIQAAF LNESQFQYFY FRTGTTLLKA LDDEKKGERL
210 220 230 240 250
PSSSSTNEEE TLRIGKLKAK IISKGLPVRF YSDLHELGEL VFKDWSVVIE
260 270 280 290 300
KLHPATLMIE NIDYKHSFER FYHEEFTEKC KQMCVISKES DRTFEILEKF
310 320 330 340 350
ALKDVELDFN NVAADSSLDS VPRFFRINPT PTYKSILLLS REHGCGKSTL
360 370 380 390 400
IANWVNYFKK KHPSMLLIPH FVGSTCESSY IMSVIHYFIT ELQYRNYGTQ
410 420 430 440 450
LETDILNEDS DGLVFSFLVE VFIASISLKP CILVLDGIEE LIGIYGISGQ
460 470 480 490 500
KVKDFSWLPH SLSPHCKFIM STVSSSLSYK SLCARPDVRT VELISTGDEE
510 520 530 540 550
TKLNIFRKHL SIPMMDPFEQ STQALRKKPD LSPLKLTILA NELKEYRINH
560 570 580 590 600
NEFQCMKEYL EAVSVQELWE LVLKRWIEDY SWTFQPKRAN SDTVASGEGL
610 620 630 640 650
DSWVADALCL LCLSHGGLAE DELLQLLDML GYRNHYKVTA LHWAAFRNAT
660 670 680 690 700
KQWVQEKPNG LLYFWHQSLS AVEHKLLGVI TPVESSPCSF QTPMNHKKTH
710 720 730 740 750
FHQVLIRYFQ RQTSFWRVYQ ELPWHMKMSG CLRGLCGFLS SPTITDFISK
760 770 780 790 800
IQSLGFWTRL HLIHFWNVLL EAGYDVSEAY LLSVAKIKAD QCHTMRKSGT
810 820 830 840 850
LSVLQCRLIE LTVLDKCRLM FFIGSFLKFM GKTNEAEELF LSVEDMLVQS
860 870 880 890 900
QSMTDMLLKV QNAIGELYLE TGMTQEGFQY FQKAWSSMLR LSLSDLEDSR
910 920 930 940 950
DLVKQKVRVL DNLAKSASEE YLKENHILEY ATEISNLLDN NPRDQATMKY
960 970 980 990 1000
IEGVLMFVAG NTSLAKMKLR ECLNIRKSLF GKKNMLVGEV MEFLADLLFF
1010 1020 1030 1040 1050
PQRDSKKSQR KQVLKYYKQV IKIKENAETL AKSSLLRKQL SISLSDTLCK
1060 1070 1080 1090 1100
LAGHLLASDS CHHVMIEAVG YLYRSVDLRV IHLGSSHSSI HGIHGILHLL
1110 1120 1130 1140 1150
REIEWIRSRR YWPQGMSQQH SEGSRNGFSL WEHLVKLNYH SAQSSNTVSS
1160 1170 1180 1190 1200
AMCMNADKLH RARRMDLAPQ TISDKSKCAP GKGKKKPIIC ISAEEKIQRK
1210 1220 1230 1240 1250
TQNNAEIWNG SGKEASKKKT DYSSNILSLG KMNGLIKLSR QRILLAKSES
1260 1270 1280 1290 1300
GEGEITTIYH HPLPWPVSTK NPGESEFISE KWLFHSPDYI SISQKSFLQR
1310
RLHIETKLLK TSNDINKE
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_034494 | 140 – 1318 | Missing in isoform 3. 1 PublicationAdd BLAST | 1179 | |
Alternative sequenceiVSP_034495 | 1053 | G → F in isoform 2. 1 Publication | 1 | |
Alternative sequenceiVSP_034496 | 1054 – 1318 | Missing in isoform 2. 1 PublicationAdd BLAST | 265 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC012386 Genomic DNA No translation available. AC012555 Genomic DNA No translation available. AC084199 Genomic DNA No translation available. BC016335 mRNA No translation available. BC064342 mRNA No translation available. |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC012386 Genomic DNA No translation available. AC012555 Genomic DNA No translation available. AC084199 Genomic DNA No translation available. BC016335 mRNA No translation available. BC064342 mRNA No translation available. |
3D structure databases
SMRi | Q6P2S7 |
ModBasei | Search... |
Protein-protein interaction databases
IntActi | Q6P2S7, 1 interactor |
PTM databases
iPTMneti | Q6P2S7 |
PhosphoSitePlusi | Q6P2S7 |
Genetic variation databases
BioMutai | HGNC:49210 |
DMDMi | 193806376 |
Proteomic databases
EPDi | Q6P2S7 |
MassIVEi | Q6P2S7 |
PRIDEi | Q6P2S7 |
ProteomicsDBi | 66919 [Q6P2S7-1] 66920 [Q6P2S7-2] 66921 [Q6P2S7-3] |
Organism-specific databases
GeneCardsi | TTC41P |
HGNCi | HGNC:49210, TTC41P |
neXtProti | NX_Q6P2S7 |
GenAtlasi | Search... |
Phylogenomic databases
InParanoidi | Q6P2S7 |
PhylomeDBi | Q6P2S7 |
Enzyme and pathway databases
PathwayCommonsi | Q6P2S7 |
Miscellaneous databases
Pharosi | Q6P2S7, Tdark |
RNActi | Q6P2S7, protein |
Family and domain databases
Gene3Di | 1.25.40.10, 1 hit |
InterProi | View protein in InterPro IPR027417, P-loop_NTPase IPR011990, TPR-like_helical_dom_sf |
SUPFAMi | SSF52540, SSF52540, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | TTC41_HUMAN | |
Accessioni | Q6P2S7Primary (citable) accession number: Q6P2S7 Secondary accession number(s): Q05DD4 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | March 18, 2008 |
Last sequence update: | July 1, 2008 | |
Last modified: | October 7, 2020 | |
This is version 103 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Human chromosome 12
Human chromosome 12: entries, gene names and cross-references to MIM