UniProtKB - Q6P2R3 (Q6P2R3_HUMAN)
Protein
Submitted name:
C6orf182 protein
Gene
CEP57L1
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- gamma-tubulin binding Source: InterPro
- identical protein binding Source: InterPro
Names & Taxonomyi
Protein namesi | Submitted name: C6orf182 proteinImportedSubmitted name: Centrosomal protein CEP57L1ImportedSubmitted name: Chromosome 6 open reading frame 182, isoform CRA_cImported |
Gene namesi | ORF Names:hCG_34126Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:21561 CEP57L1 |
Expressioni
Gene expression databases
Bgeei | ENSG00000183137 Expressed in 123 organ(s), highest expression level in testis |
Interactioni
Binary interactionsi
GO - Molecular functioni
- gamma-tubulin binding Source: InterPro
- identical protein binding Source: InterPro
Protein-protein interaction databases
IntActi | Q6P2R3, 5 interactors |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 54 – 231 | Cep57_CLDInterPro annotationAdd BLAST | 178 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 52 – 114 | Sequence analysisAdd BLAST | 63 | |
Coiled coili | 140 – 163 | Sequence analysisAdd BLAST | 24 | |
Coiled coili | 189 – 216 | Sequence analysisAdd BLAST | 28 |
Keywords - Domaini
Coiled coilSequence analysisPhylogenomic databases
eggNOGi | ENOG410IVGR Eukaryota ENOG410XT4F LUCA |
GeneTreei | ENSGT00530000063695 |
HOGENOMi | HOG000143392 |
Family and domain databases
InterProi | View protein in InterPro IPR025913 Cep57_CLD |
Pfami | View protein in Pfam PF14073 Cep57_CLD, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 18 potential isoforms that are computationally mapped.Show allAlign All
Q6P2R3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDSELMHSIV GSYHKPPERV FVPSFTQNEP SQNCHPANLE VTSPKILHSP
60 70 80 90 100
NSQALILALK TLQEKIHRLE LERTQAEDNL NILSREAAQY KKALENETNE
110 120 130 140 150
RNLAHQELIK QKKDISIQLS SAQSRCTLLE KQLEYTKRMV LNVEREKNMI
160 170 180 190 200
LEQQAQLQRE KEQDQMKLYA KLEKLDVLEK ECFRLTTTQK TAEDKIKHLE
210 220 230 240 250
EKLKEEEHQR KLFQDKASEL QTGLEISKII MSSVSNLKHS KEKKKSSKVC
I
Computationally mapped potential isoform sequencesi
There are 18 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ8IYX8 | CE57L_HUMAN | Centrosomal protein CEP57L1 | CEP57L1 C6orf182, CEP57R | 460 | Annotation score: | ||
G3V140 | G3V140_HUMAN | Centrosomal protein CEP57L1 | CEP57L1 C6orf182, hCG_34126 | 463 | Annotation score: | ||
E5RFY4 | E5RFY4_HUMAN | Centrosomal protein CEP57L1 | CEP57L1 | 477 | Annotation score: | ||
Q5T6A0 | Q5T6A0_HUMAN | Centrosomal protein CEP57L1 | CEP57L1 | 360 | Annotation score: | ||
E5RIV2 | E5RIV2_HUMAN | Centrosomal protein CEP57L1 | CEP57L1 | 407 | Annotation score: | ||
E5RG21 | E5RG21_HUMAN | Centrosomal protein CEP57L1 | CEP57L1 | 230 | Annotation score: | ||
E5RG82 | E5RG82_HUMAN | Centrosomal protein CEP57L1 | CEP57L1 | 195 | Annotation score: | ||
E5RHF8 | E5RHF8_HUMAN | Centrosomal protein CEP57L1 | CEP57L1 | 206 | Annotation score: | ||
E5RGP2 | E5RGP2_HUMAN | Centrosomal protein CEP57L1 | CEP57L1 | 166 | Annotation score: | ||
E5RI49 | E5RI49_HUMAN | Centrosomal protein CEP57L1 | CEP57L1 | 113 | Annotation score: | ||
There are more potential isoformsShow all |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL355305 Genomic DNA No translation available. BC064365 mRNA Translation: AAH64365.1 CH471051 Genomic DNA Translation: EAW48363.1 |
Genome annotation databases
Ensembli | ENST00000407272; ENSP00000383936; ENSG00000183137 ENST00000519095; ENSP00000430911; ENSG00000183137 |
UCSCi | uc003psw.5 human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL355305 Genomic DNA No translation available. BC064365 mRNA Translation: AAH64365.1 CH471051 Genomic DNA Translation: EAW48363.1 |
3D structure databases
SMRi | Q6P2R3 |
ModBasei | Search... |
Protein-protein interaction databases
IntActi | Q6P2R3, 5 interactors |
Proteomic databases
ProteomicsDBi | 66918 |
Genome annotation databases
Ensembli | ENST00000407272; ENSP00000383936; ENSG00000183137 ENST00000519095; ENSP00000430911; ENSG00000183137 |
UCSCi | uc003psw.5 human |
Organism-specific databases
HGNCi | HGNC:21561 CEP57L1 |
OpenTargetsi | ENSG00000183137 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | ENOG410IVGR Eukaryota ENOG410XT4F LUCA |
GeneTreei | ENSGT00530000063695 |
HOGENOMi | HOG000143392 |
Miscellaneous databases
ChiTaRSi | CEP57L1 human |
Gene expression databases
Bgeei | ENSG00000183137 Expressed in 123 organ(s), highest expression level in testis |
Family and domain databases
InterProi | View protein in InterPro IPR025913 Cep57_CLD |
Pfami | View protein in Pfam PF14073 Cep57_CLD, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q6P2R3_HUMAN | |
Accessioni | Q6P2R3Primary (citable) accession number: Q6P2R3 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 5, 2004 |
Last sequence update: | July 5, 2004 | |
Last modified: | November 13, 2019 | |
This is version 119 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |