UniProtKB - Q6P1M3 (L2GL2_HUMAN)
Protein
LLGL scribble cell polarity complex component 2
Gene
LLGL2
Organism
Homo sapiens (Human)
Status
Functioni
Part of a complex with GPSM2/LGN, PRKCI/aPKC and PARD6B/Par-6, which may ensure the correct organization and orientation of bipolar spindles for normal cell division. This complex plays roles in the initial phase of the establishment of epithelial cell polarity.1 Publication
Miscellaneous
Overexpression of LLGL2 inhibits the tight junction formation.
GO - Molecular functioni
- GTPase activator activity Source: GO_Central
- myosin II binding Source: GO_Central
- PDZ domain binding Source: UniProtKB
GO - Biological processi
- cell division Source: UniProtKB-KW
- cortical actin cytoskeleton organization Source: GO_Central
- establishment of spindle orientation Source: GO_Central
- exocytosis Source: UniProtKB-KW
- leucine transport Source: UniProtKB
- regulation of establishment or maintenance of cell polarity Source: UniProtKB
- regulation of Notch signaling pathway Source: GO_Central
- regulation of protein secretion Source: GO_Central
Keywordsi
Biological process | Cell cycle, Cell division, Exocytosis |
Enzyme and pathway databases
PathwayCommonsi | Q6P1M3 |
SignaLinki | Q6P1M3 |
Names & Taxonomyi
Protein namesi | Recommended name: LLGL scribble cell polarity complex component 2Alternative name(s): HGL Lethal(2) giant larvae protein homolog 2 |
Gene namesi | Name:LLGL2 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:6629, LLGL2 |
MIMi | 618483, gene |
neXtProti | NX_Q6P1M3 |
VEuPathDBi | HostDB:ENSG00000073350.13 |
Subcellular locationi
Cytoplasm and Cytosol
- Cytoplasm 1 Publication
Note: Localized in the perinuclear structure and faintly at the cell-cell contacts sites in the interphase. Localized at the cell periphery during metaphase. Cortical localization in mitotic cells. Found in the lateral region of polarized epithelial cells.
Cytoskeleton
- cortical actin cytoskeleton Source: GO_Central
Cytosol
- cytosol Source: HPA
Plasma Membrane
- plasma membrane Source: GO_Central
Other locations
- cytoplasm Source: UniProtKB
- intracellular membrane-bounded organelle Source: HPA
Keywords - Cellular componenti
CytoplasmPathology & Biotechi
Mutagenesis
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Mutagenesisi | 641 | S → A: No effect on phosphorylation. 1 Publication | 1 | |
Mutagenesisi | 645 | S → A: Decrease of phosphorylation. 1 Publication | 1 | |
Mutagenesisi | 649 | S → A: Decrease of phosphorylation. 1 Publication | 1 | |
Mutagenesisi | 653 | S → A: Loss of phosphorylation. 1 Publication | 1 | |
Mutagenesisi | 660 | S → A: Decrease of phosphorylation. 1 Publication | 1 | |
Mutagenesisi | 663 | S → A: No effect on phosphorylation. 1 Publication | 1 |
Organism-specific databases
DisGeNETi | 3993 |
OpenTargetsi | ENSG00000073350 |
PharmGKBi | PA30397 |
Miscellaneous databases
Pharosi | Q6P1M3, Tbio |
Genetic variation databases
BioMutai | LLGL2 |
DMDMi | 93204600 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000232728 | 1 – 1020 | LLGL scribble cell polarity complex component 2Add BLAST | 1020 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 653 | Phosphoserine1 Publication | 1 | |
Modified residuei | 965 | PhosphoserineCombined sources | 1 | |
Modified residuei | 1015 | PhosphoserineCombined sources | 1 |
Post-translational modificationi
Phosphorylated at Ser-653 by PRKCI. Phosphorylation is enhanced during cell polarization induced by calcium. Phosphorylation may occur during the cell-cell contact-induced cell polarization and may contribute to the segregation of LLGL2 from the PRKCI/aPKC and PARD6B/Par-6 complex.1 Publication
Keywords - PTMi
PhosphoproteinProteomic databases
EPDi | Q6P1M3 |
jPOSTi | Q6P1M3 |
MassIVEi | Q6P1M3 |
MaxQBi | Q6P1M3 |
PaxDbi | Q6P1M3 |
PeptideAtlasi | Q6P1M3 |
PRIDEi | Q6P1M3 |
ProteomicsDBi | 66850 [Q6P1M3-1] 66851 [Q6P1M3-2] 66852 [Q6P1M3-3] |
PTM databases
iPTMneti | Q6P1M3 |
PhosphoSitePlusi | Q6P1M3 |
Expressioni
Gene expression databases
Bgeei | ENSG00000073350, Expressed in mucosa of transverse colon and 191 other tissues |
ExpressionAtlasi | Q6P1M3, baseline and differential |
Genevisiblei | Q6P1M3, HS |
Organism-specific databases
HPAi | ENSG00000073350, Low tissue specificity |
Interactioni
Subunit structurei
Interacts with GPSM2/LGN, PRKCI/aPKC and PARD6B/Par-6. The complex is enhanced during mitosis.
Interacts with DCAF1.
3 PublicationsGO - Molecular functioni
- myosin II binding Source: GO_Central
- PDZ domain binding Source: UniProtKB
Protein-protein interaction databases
BioGRIDi | 110181, 107 interactors |
ComplexPortali | CPX-6168, Scribble cell polarity complex, DLG1-LLGL2-SCRIB variant CPX-6184, Scribble cell polarity complex, DLG2-LLGL2-SCRIB variant CPX-6185, Scribble cell polarity complex, DLG3-LLGL2-SCRIB variant CPX-6186, Scribble cell polarity complex, DLG4-LLGL2-SCRIB variant CPX-6187, Scribble cell polarity complex, DLG5-LLGL2-SCRIB variant |
CORUMi | Q6P1M3 |
IntActi | Q6P1M3, 87 interactors |
STRINGi | 9606.ENSP00000376333 |
Miscellaneous databases
RNActi | Q6P1M3, protein |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | Q6P1M3 |
ModBasei | Search... |
PDBe-KBi | Search... |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 36 – 69 | WD 1Add BLAST | 34 | |
Repeati | 76 – 117 | WD 2Add BLAST | 42 | |
Repeati | 132 – 169 | WD 3Add BLAST | 38 | |
Repeati | 193 – 227 | WD 4Add BLAST | 35 | |
Repeati | 233 – 268 | WD 5Add BLAST | 36 | |
Repeati | 282 – 324 | WD 6Add BLAST | 43 | |
Repeati | 332 – 366 | WD 7Add BLAST | 35 | |
Repeati | 388 – 464 | WD 8Add BLAST | 77 | |
Repeati | 508 – 583 | WD 9Add BLAST | 76 | |
Repeati | 592 – 653 | WD 10Add BLAST | 62 | |
Repeati | 713 – 769 | WD 11Add BLAST | 57 | |
Repeati | 778 – 830 | WD 12Add BLAST | 53 | |
Repeati | 835 – 888 | WD 13Add BLAST | 54 | |
Repeati | 902 – 925 | WD 14Add BLAST | 24 |
Sequence similaritiesi
Belongs to the WD repeat L(2)GL family.Curated
Keywords - Domaini
Repeat, WD repeatPhylogenomic databases
eggNOGi | KOG1983, Eukaryota |
GeneTreei | ENSGT00950000182906 |
HOGENOMi | CLU_046862_0_0_1 |
InParanoidi | Q6P1M3 |
OMAi | SWYHADG |
OrthoDBi | 122541at2759 |
PhylomeDBi | Q6P1M3 |
TreeFami | TF314585 |
Family and domain databases
Gene3Di | 2.130.10.10, 1 hit |
InterProi | View protein in InterPro IPR000664, Lethal2_giant IPR013577, LLGL2 IPR015943, WD40/YVTN_repeat-like_dom_sf IPR001680, WD40_repeat IPR019775, WD40_repeat_CS IPR036322, WD40_repeat_dom_sf |
Pfami | View protein in Pfam PF08366, LLGL, 1 hit PF00400, WD40, 1 hit |
PRINTSi | PR00962, LETHAL2GIANT |
SMARTi | View protein in SMART SM00320, WD40, 5 hits |
SUPFAMi | SSF50978, SSF50978, 2 hits |
PROSITEi | View protein in PROSITE PS00678, WD_REPEATS_1, 1 hit PS50082, WD_REPEATS_2, 1 hit |
s (3+)i Sequence
Sequence statusi: Complete.
This entry describes 3 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 3 described isoforms and 10 potential isoforms that are computationally mapped.Show allAlign All
Isoform C (identifier: Q6P1M3-1) [UniParc]FASTAAdd to basket
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MRRFLRPGHD PVRERLKRDL FQFNKTVEHG FPHQPSALGY SPSLRILAIG
60 70 80 90 100
TRSGAIKLYG APGVEFMGLH QENNAVTQIH LLPGQCQLVT LLDDNSLHLW
110 120 130 140 150
SLKVKGGASE LQEDESFTLR GPPGAAPSAT QITVVLPHSS CELLYLGTES
160 170 180 190 200
GNVFVVQLPA FRALEDRTIS SDAVLQRLPE EARHRRVFEM VEALQEHPRD
210 220 230 240 250
PNQILIGYSR GLVVIWDLQG SRVLYHFLSS QQLENIWWQR DGRLLVSCHS
260 270 280 290 300
DGSYCQWPVS SEAQQPEPLR SLVPYGPFPC KAITRILWLT TRQGLPFTIF
310 320 330 340 350
QGGMPRASYG DRHCISVIHD GQQTAFDFTS RVIGFTVLTE ADPAATFDDP
360 370 380 390 400
YALVVLAEEE LVVIDLQTAG WPPVQLPYLA SLHCSAITCS HHVSNIPLKL
410 420 430 440 450
WERIIAAGSR QNAHFSTMEW PIDGGTSLTP APPQRDLLLT GHEDGTVRFW
460 470 480 490 500
DASGVCLRLL YKLSTVRVFL TDTDPNENFS AQGEDEWPPL RKVGSFDPYS
510 520 530 540 550
DDPRLGIQKI FLCKYSGYLA VAGTAGQVLV LELNDEAAEQ AVEQVEADLL
560 570 580 590 600
QDQEGYRWKG HERLAARSGP VRFEPGFQPF VLVQCQPPAV VTSLALHSEW
610 620 630 640 650
RLVAFGTSHG FGLFDHQQRR QVFVKCTLHP SDQLALEGPL SRVKSLKKSL
660 670 680 690 700
RQSFRRMRRS RVSSRKRHPA GPPGEAQEGS AKAERPGLQN MELAPVQRKI
710 720 730 740 750
EARSAEDSFT GFVRTLYFAD TYLKDSSRHC PSLWAGTNGG TIYAFSLRVP
760 770 780 790 800
PAERRMDEPV RAEQAKEIQL MHRAPVVGIL VLDGHSVPLP EPLEVAHDLS
810 820 830 840 850
KSPDMQGSHQ LLVVSEEQFK VFTLPKVSAK LKLKLTALEG SRVRRVSVAH
860 870 880 890 900
FGSRRAEDYG EHHLAVLTNL GDIQVVSLPL LKPQVRYSCI RREDVSGIAS
910 920 930 940 950
CVFTKYGQGF YLISPSEFER FSLSTKWLVE PRCLVDSAET KNHRPGNGAG
960 970 980 990 1000
PKKAPSRARN SGTQSDGEEK QPGLVMERAL LSDERVLKEI QSTLEGDRGS
1010 1020
GNWRSHRAAV GCSLSNGGAE
Computationally mapped potential isoform sequencesi
There are 10 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketJ3QRV5 | J3QRV5_HUMAN | LLGL scribble cell polarity complex... | LLGL2 | 1,019 | Annotation score: | ||
J3QLV4 | J3QLV4_HUMAN | LLGL scribble cell polarity complex... | LLGL2 | 103 | Annotation score: | ||
J3KSD5 | J3KSD5_HUMAN | LLGL scribble cell polarity complex... | LLGL2 | 62 | Annotation score: | ||
J3QKM6 | J3QKM6_HUMAN | LLGL scribble cell polarity complex... | LLGL2 | 105 | Annotation score: | ||
J3QL58 | J3QL58_HUMAN | LLGL scribble cell polarity complex... | LLGL2 | 139 | Annotation score: | ||
J3QS20 | J3QS20_HUMAN | LLGL scribble cell polarity complex... | LLGL2 | 156 | Annotation score: | ||
J3QLD8 | J3QLD8_HUMAN | LLGL scribble cell polarity complex... | LLGL2 | 86 | Annotation score: | ||
J3QRZ8 | J3QRZ8_HUMAN | LLGL scribble cell polarity complex... | LLGL2 | 105 | Annotation score: | ||
J3QSA6 | J3QSA6_HUMAN | LLGL scribble cell polarity complex... | LLGL2 | 150 | Annotation score: | ||
J3KRE1 | J3KRE1_HUMAN | LLGL scribble cell polarity complex... | LLGL2 | 39 | Annotation score: |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_050069 | 45 | R → H1 PublicationCorresponds to variant dbSNP:rs1671036Ensembl. | 1 | |
Natural variantiVAR_050070 | 479 | F → L1 PublicationCorresponds to variant dbSNP:rs1671021Ensembl. | 1 | |
Natural variantiVAR_050071 | 488 | P → L. Corresponds to variant dbSNP:rs35991442Ensembl. | 1 | |
Natural variantiVAR_050072 | 490 | L → P. Corresponds to variant dbSNP:rs1671021Ensembl. | 1 | |
Natural variantiVAR_034058 | 748 | R → H. Corresponds to variant dbSNP:rs35474687EnsemblClinVar. | 1 | |
Natural variantiVAR_050073 | 759 | P → S1 PublicationCorresponds to variant dbSNP:rs1661715Ensembl. | 1 | |
Natural variantiVAR_050075 | 790 | P → L. Corresponds to variant dbSNP:rs1661714Ensembl. | 1 | |
Natural variantiVAR_034059 | 1001 | G → S. Corresponds to variant dbSNP:rs35886912Ensembl. | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_047387 | 346 – 356 | TFDDPYALVVL → SRRASGVGAQG in isoform B. 1 PublicationAdd BLAST | 11 | |
Alternative sequenceiVSP_047388 | 357 – 1020 | Missing in isoform B. 1 PublicationAdd BLAST | 664 | |
Alternative sequenceiVSP_017946 | 986 – 1020 | VLKEI…NGGAE → AATGVHIEPPWGAASAMAEQ SEWLSVQAAR in isoform A. 1 PublicationAdd BLAST | 35 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X87342 mRNA Translation: CAA60780.1 AC100787 Genomic DNA No translation available. BC006503 mRNA Translation: AAH06503.1 BC010879 mRNA Translation: AAH10879.1 BC064994 mRNA Translation: AAH64994.1 |
CCDSi | CCDS11725.1 [Q6P1M3-2] CCDS32733.1 [Q6P1M3-1] CCDS45776.1 [Q6P1M3-3] |
PIRi | S55474 |
RefSeqi | NP_001015002.1, NM_001015002.1 [Q6P1M3-3] NP_001026973.1, NM_001031803.1 [Q6P1M3-1] NP_004515.2, NM_004524.2 [Q6P1M3-2] XP_016880115.1, XM_017024626.1 [Q6P1M3-1] XP_016880119.1, XM_017024630.1 [Q6P1M3-2] |
Genome annotation databases
Ensembli | ENST00000167462; ENSP00000167462; ENSG00000073350 [Q6P1M3-2] ENST00000375227; ENSP00000364375; ENSG00000073350 [Q6P1M3-3] ENST00000392550; ENSP00000376333; ENSG00000073350 [Q6P1M3-1] ENST00000578363; ENSP00000464603; ENSG00000073350 [Q6P1M3-3] |
GeneIDi | 3993 |
KEGGi | hsa:3993 |
UCSCi | uc002jog.2, human [Q6P1M3-1] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X87342 mRNA Translation: CAA60780.1 AC100787 Genomic DNA No translation available. BC006503 mRNA Translation: AAH06503.1 BC010879 mRNA Translation: AAH10879.1 BC064994 mRNA Translation: AAH64994.1 |
CCDSi | CCDS11725.1 [Q6P1M3-2] CCDS32733.1 [Q6P1M3-1] CCDS45776.1 [Q6P1M3-3] |
PIRi | S55474 |
RefSeqi | NP_001015002.1, NM_001015002.1 [Q6P1M3-3] NP_001026973.1, NM_001031803.1 [Q6P1M3-1] NP_004515.2, NM_004524.2 [Q6P1M3-2] XP_016880115.1, XM_017024626.1 [Q6P1M3-1] XP_016880119.1, XM_017024630.1 [Q6P1M3-2] |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
3WP0 | X-ray | 2.04 | B | 640-654 | [»] | |
3WP1 | X-ray | 2.80 | A | 646-657 | [»] | |
6N8P | X-ray | 3.19 | A | 12-978 | [»] | |
6N8Q | X-ray | 2.20 | A | 12-978 | [»] | |
6N8R | X-ray | 1.91 | A | 12-978 | [»] | |
6N8S | X-ray | 3.90 | A/D | 12-978 | [»] | |
SMRi | Q6P1M3 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 110181, 107 interactors |
ComplexPortali | CPX-6168, Scribble cell polarity complex, DLG1-LLGL2-SCRIB variant CPX-6184, Scribble cell polarity complex, DLG2-LLGL2-SCRIB variant CPX-6185, Scribble cell polarity complex, DLG3-LLGL2-SCRIB variant CPX-6186, Scribble cell polarity complex, DLG4-LLGL2-SCRIB variant CPX-6187, Scribble cell polarity complex, DLG5-LLGL2-SCRIB variant |
CORUMi | Q6P1M3 |
IntActi | Q6P1M3, 87 interactors |
STRINGi | 9606.ENSP00000376333 |
PTM databases
iPTMneti | Q6P1M3 |
PhosphoSitePlusi | Q6P1M3 |
Genetic variation databases
BioMutai | LLGL2 |
DMDMi | 93204600 |
Proteomic databases
EPDi | Q6P1M3 |
jPOSTi | Q6P1M3 |
MassIVEi | Q6P1M3 |
MaxQBi | Q6P1M3 |
PaxDbi | Q6P1M3 |
PeptideAtlasi | Q6P1M3 |
PRIDEi | Q6P1M3 |
ProteomicsDBi | 66850 [Q6P1M3-1] 66851 [Q6P1M3-2] 66852 [Q6P1M3-3] |
Protocols and materials databases
Antibodypediai | 19581, 200 antibodies |
Genome annotation databases
Ensembli | ENST00000167462; ENSP00000167462; ENSG00000073350 [Q6P1M3-2] ENST00000375227; ENSP00000364375; ENSG00000073350 [Q6P1M3-3] ENST00000392550; ENSP00000376333; ENSG00000073350 [Q6P1M3-1] ENST00000578363; ENSP00000464603; ENSG00000073350 [Q6P1M3-3] |
GeneIDi | 3993 |
KEGGi | hsa:3993 |
UCSCi | uc002jog.2, human [Q6P1M3-1] |
Organism-specific databases
CTDi | 3993 |
DisGeNETi | 3993 |
GeneCardsi | LLGL2 |
HGNCi | HGNC:6629, LLGL2 |
HPAi | ENSG00000073350, Low tissue specificity |
MIMi | 618483, gene |
neXtProti | NX_Q6P1M3 |
OpenTargetsi | ENSG00000073350 |
PharmGKBi | PA30397 |
VEuPathDBi | HostDB:ENSG00000073350.13 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG1983, Eukaryota |
GeneTreei | ENSGT00950000182906 |
HOGENOMi | CLU_046862_0_0_1 |
InParanoidi | Q6P1M3 |
OMAi | SWYHADG |
OrthoDBi | 122541at2759 |
PhylomeDBi | Q6P1M3 |
TreeFami | TF314585 |
Enzyme and pathway databases
PathwayCommonsi | Q6P1M3 |
SignaLinki | Q6P1M3 |
Miscellaneous databases
BioGRID-ORCSi | 3993, 9 hits in 994 CRISPR screens |
ChiTaRSi | LLGL2, human |
GenomeRNAii | 3993 |
Pharosi | Q6P1M3, Tbio |
PROi | PR:Q6P1M3 |
RNActi | Q6P1M3, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000073350, Expressed in mucosa of transverse colon and 191 other tissues |
ExpressionAtlasi | Q6P1M3, baseline and differential |
Genevisiblei | Q6P1M3, HS |
Family and domain databases
Gene3Di | 2.130.10.10, 1 hit |
InterProi | View protein in InterPro IPR000664, Lethal2_giant IPR013577, LLGL2 IPR015943, WD40/YVTN_repeat-like_dom_sf IPR001680, WD40_repeat IPR019775, WD40_repeat_CS IPR036322, WD40_repeat_dom_sf |
Pfami | View protein in Pfam PF08366, LLGL, 1 hit PF00400, WD40, 1 hit |
PRINTSi | PR00962, LETHAL2GIANT |
SMARTi | View protein in SMART SM00320, WD40, 5 hits |
SUPFAMi | SSF50978, SSF50978, 2 hits |
PROSITEi | View protein in PROSITE PS00678, WD_REPEATS_1, 1 hit PS50082, WD_REPEATS_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | L2GL2_HUMAN | |
Accessioni | Q6P1M3Primary (citable) accession number: Q6P1M3 Secondary accession number(s): Q14521, Q9BR62 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 18, 2006 |
Last sequence update: | April 18, 2006 | |
Last modified: | April 7, 2021 | |
This is version 157 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- Human chromosome 17
Human chromosome 17: entries, gene names and cross-references to MIM - Human entries with genetic variants
List of human entries with genetic variants - Human variants curated from literature reports
Index of human variants curated from literature reports - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families