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Protein
Submitted name:

Exostoses (Multiple)-like 3

Gene

Extl3

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Exostoses (Multiple)-like 3Imported
Submitted name:
Exostosin-like 3Imported
Gene namesi
Name:Extl3Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 14

Organism-specific databases

MGIiMGI:1860765 Extl3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei29 – 51HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000021978 Expressed in 370 organ(s), highest expression level in pancreas

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini663 – 904Glyco_transf_64InterPro annotationAdd BLAST242

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili86 – 148Sequence analysisAdd BLAST63

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG2264 Eukaryota
ENOG410XNPM LUCA
GeneTreeiENSGT00550000074496
HOVERGENiHBG051526
OMAiRKSDTQN
OrthoDBiEOG091G03XP
TreeFamiTF314231

Family and domain databases

Gene3Di3.90.550.10, 1 hit
InterProiView protein in InterPro
IPR004263 Exostosin
IPR015338 EXT_C
IPR029044 Nucleotide-diphossugar_trans
PANTHERiPTHR11062 PTHR11062, 1 hit
PfamiView protein in Pfam
PF03016 Exostosin, 1 hit
PF09258 Glyco_transf_64, 1 hit
SUPFAMiSSF53448 SSF53448, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q6P1H4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTGYTMLRNG GVGNGGQTCM LRWSNRIRLT WLSFTLFIIL VFFPLIAHYY
60 70 80 90 100
LTTLDEADEA GKRIFGPRAG SELCEVKHVL DLCRIRESVS EELLQLEAKR
110 120 130 140 150
QELNSEIAKL NLKIEACKKS IENAKQDLLQ LKNVISQTEH SYKELMAQNQ
160 170 180 190 200
PKLSLPIRLL PEKDDAGLPP PKVTRGCRLH NCFDYSRCPL TSGFPVYVYD
210 220 230 240 250
SDQFAFGSYL DPLVKQAFQA TVRANVYVTE NAAIACLYVV LVGEMQEPTV
260 270 280 290 300
LRPADLEKQL FSLPHWRTDG HNHVIINLSR KSDTQNLLYN VSTGRAMVAQ
310 320 330 340 350
STFYAAQYRA GFDLVVSPLV HAMSEPNFME IPPQVPVKRK YLFTFQGEKI
360 370 380 390 400
ESLRSSLQEA RSFEEEMEGD PPADYDDRII ATLKAVQDSK LDQVLVEFTC
410 420 430 440 450
KNQPKPSLPT EWALCGERED RLELLKLSTF ALIITPGDPH LLISSGCATR
460 470 480 490 500
LFEALEVGAV PVVLGEQVQL PYHDMLQWNE AALVVPKPRV TEVHFLLRSL
510 520 530 540 550
SDSDLLAMRR QGRFLWETYF STADSIFNTV LAMIRTRIQI PAAPIREEVA
560 570 580 590 600
AEIPHRSGKA AGTDPNMADN GDLDLGPVET EPPYASPKYL RNFTLTVTDC
610 620 630 640 650
YRGWNSAPGP FHLFPHTPFD PVLPSEAKFL GSGTGFRPIG GGAGGSGKEF
660 670 680 690 700
QAALGGNVQR EQFTVVMLTY EREEVLMNSL ERLNGLPYLN KVVVVWNSPK
710 720 730 740 750
LPSEDLLWPD IGVPIMVVRT EKNSLNNRFL PWNEIETEAI LSIDDDAHLR
760 770 780 790 800
HDEIMFGFRV WREARDRIVG FPGRYHAWDI PHQSWLYNSN YSCELSMVLT
810 820 830 840 850
GAAFFHKYYA YLYSYVMPQA IRDMVDEYIN CEDIAMNFLV SHITRKPPIK
860 870 880 890 900
VTSRWTFRCP GCPQALSHDD SHFHERHKCI NFFVKVYGYM PLLYTQFRVD
910
SVLFKTRLPH DKTKCFKFI
Length:919
Mass (Da):104,539
Last modified:July 5, 2004 - v1
Checksum:i8342A24745CCCBF0
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9WVL6EXTL3_MOUSE
Exostosin-like 3
Extl3
918Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124489 Genomic DNA No translation available.
AC155172 Genomic DNA No translation available.
BC065073 mRNA Translation: AAH65073.1
RefSeqiNP_061258.2, NM_018788.3
XP_006519347.1, XM_006519284.2
XP_006519348.1, XM_006519285.3
XP_006519349.1, XM_006519286.3
UniGeneiMm.103748

Genome annotation databases

EnsembliENSMUST00000022550; ENSMUSP00000022550; ENSMUSG00000021978
ENSMUST00000225633; ENSMUSP00000153547; ENSMUSG00000021978
GeneIDi54616
UCSCiuc007uix.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124489 Genomic DNA No translation available.
AC155172 Genomic DNA No translation available.
BC065073 mRNA Translation: AAH65073.1
RefSeqiNP_061258.2, NM_018788.3
XP_006519347.1, XM_006519284.2
XP_006519348.1, XM_006519285.3
XP_006519349.1, XM_006519286.3
UniGeneiMm.103748

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000022550; ENSMUSP00000022550; ENSMUSG00000021978
ENSMUST00000225633; ENSMUSP00000153547; ENSMUSG00000021978
GeneIDi54616
UCSCiuc007uix.2 mouse

Organism-specific databases

CTDi2137
MGIiMGI:1860765 Extl3

Phylogenomic databases

eggNOGiKOG2264 Eukaryota
ENOG410XNPM LUCA
GeneTreeiENSGT00550000074496
HOVERGENiHBG051526
OMAiRKSDTQN
OrthoDBiEOG091G03XP
TreeFamiTF314231

Miscellaneous databases

ChiTaRSiExtl3 mouse
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000021978 Expressed in 370 organ(s), highest expression level in pancreas

Family and domain databases

Gene3Di3.90.550.10, 1 hit
InterProiView protein in InterPro
IPR004263 Exostosin
IPR015338 EXT_C
IPR029044 Nucleotide-diphossugar_trans
PANTHERiPTHR11062 PTHR11062, 1 hit
PfamiView protein in Pfam
PF03016 Exostosin, 1 hit
PF09258 Glyco_transf_64, 1 hit
SUPFAMiSSF53448 SSF53448, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ6P1H4_MOUSE
AccessioniPrimary (citable) accession number: Q6P1H4
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: October 10, 2018
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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