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Protein
Submitted name:

CDH23 protein

Gene

CDH23

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandCalciumSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
CDH23 proteinImported
Gene namesi
Name:CDH23Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA26296

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_500427821024 – 1381Sequence analysisAdd BLAST1358

Proteomic databases

PeptideAtlasiQ6P152
PRIDEiQ6P152

Expressioni

Gene expression databases

GenevisibleiQ6P152 HS

Structurei

3D structure databases

ProteinModelPortaliQ6P152
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini55 – 130CAInterPro annotationAdd BLAST76
Domaini154 – 234CAInterPro annotationAdd BLAST81
Domaini258 – 346CAInterPro annotationAdd BLAST89
Domaini371 – 458CAInterPro annotationAdd BLAST88
Domaini482 – 559CAInterPro annotationAdd BLAST78
Domaini583 – 669CAInterPro annotationAdd BLAST87
Domaini693 – 776CAInterPro annotationAdd BLAST84
Domaini800 – 888CAInterPro annotationAdd BLAST89
Domaini912 – 993CAInterPro annotationAdd BLAST82
Domaini1017 – 1100CAInterPro annotationAdd BLAST84
Domaini1124 – 1206CAInterPro annotationAdd BLAST83
Domaini1231 – 1311CAInterPro annotationAdd BLAST81

Keywords - Domaini

RepeatSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

HOGENOMiHOG000139588
HOVERGENiHBG062348
KOiK06813

Family and domain databases

InterProiView protein in InterPro
IPR002126 Cadherin-like_dom
IPR015919 Cadherin-like_sf
IPR020894 Cadherin_CS
IPR033030 CDH23
PANTHERiPTHR43956:SF3 PTHR43956:SF3, 1 hit
PfamiView protein in Pfam
PF00028 Cadherin, 12 hits
PRINTSiPR00205 CADHERIN
SMARTiView protein in SMART
SM00112 CA, 12 hits
SUPFAMiSSF49313 SSF49313, 12 hits
PROSITEiView protein in PROSITE
PS00232 CADHERIN_1, 4 hits

Sequencei

Sequence statusi: Complete.

Q6P152-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGRHVATSCH VAWLLVLISG CWGQVNRLPF FTNHFFDTYL LISEDTPVGS
60 70 80 90 100
SVTQLLAQDM DNDPLVFGVS GEEASRFFAV EPDTGVVWLR QPLDRETKSE
110 120 130 140 150
FTVEFSVSDH QGVITRKVNI QVGDVNDNAP TFHNQPYSVR IPENTPVGTP
160 170 180 190 200
IFIVNATDPD LGAGGSVLYS FQPPSQFFAI DSARGIVTVI RELDYETTQA
210 220 230 240 250
YQLTVNATDQ DKTRPLSTLA NLAIIITDVQ DMDPIFINLP YSTNIYEHSP
260 270 280 290 300
PGTTVRIITA IDQDKGRPRG IGYTIVSGNT NSIFALDYIS GVLTLNGLLD
310 320 330 340 350
RENPLYSHGF ILTVKGTELN DDRTPSDATV TTTFNILVID INDNAPEFNS
360 370 380 390 400
SEYSVAITEL AQVGFALPLF IQVVDKDENL GLNSMFEVYL VGNNSHHFII
410 420 430 440 450
SPTSVQGKAD IRIRVAIPLD YETVDRYDFD LFANESVPDH VGYAKVKITL
460 470 480 490 500
INENDNRPIF SQPLYNISLY ENVTVGTSVL TVLATDNDAG TFGEVSYFFS
510 520 530 540 550
DDPDRFSLDK DTGLIMLIAR LDYELIQRFT LTIIARDGGG EETTGRVRIN
560 570 580 590 600
VLDVNDNVPT FQKDAYVGAL RENEPSVTQL VRLRATDEDS PPNNQITYSI
610 620 630 640 650
VSASAFGSYF DISLYEGYGV ISVSRPLDYE QISNGLIYLT VMAMDAGNPP
660 670 680 690 700
LNSTVPVTIE VFDENDNPPT FSKPAYFVSV VENIMAGATV LFLNATDLDR
710 720 730 740 750
SREYGQESII YSLEGSTQFR INARSGEITT TSLLDRETKS EYILIVRAVD
760 770 780 790 800
GGVGHNQKTG IATVNITLLD INDNHPTWKD APYYINLVEM TPPDSDVTTV
810 820 830 840 850
VAVDPDLGEN GTLVYSIQPP NKFYSLNSTT GKIRTTHAML DRENPDPHEA
860 870 880 890 900
ELMRKIVVSV TDCGRPPLKA TSSATVFVNL LDLNDNDPTF QNLPFVAEVL
910 920 930 940 950
EGIPAGVSIY QVVAIDLDEG LNGLVSYRMP VGMPRMDFLI NSSSGVVVTT
960 970 980 990 1000
TELDRERIAK YQLRVVASDA GTPTKSSTST LTIHVLDVND ETPTFFPAVY
1010 1020 1030 1040 1050
NVSVSEDVPR EFRVVWLNCT DNDVGLNAEL SYFITGGNVD GKFSVGYRDA
1060 1070 1080 1090 1100
VVRTVVGLDR ETTAAYMLIL EAIDNGPVGK RHTGTATVFV TVLDVNDNRP
1110 1120 1130 1140 1150
IFLQSSYEAS VPEDIPEGHS ILQLKATDAD EGEFGRVWYR ILHGNHGNNF
1160 1170 1180 1190 1200
RIHVSNGLLM RGPRPLDRER NSSHVLIVEA YNHDLGPMRS SVRVIVYVED
1210 1220 1230 1240 1250
INDEAPVFTQ QQYSRLGLRE TAGIGTSVIV VQATDRDSGD GGLVNYRILS
1260 1270 1280 1290 1300
GAEGKFEIDE STGLIITVNY LDYETKTSYM MNVSATDQAP PFNQGFCSVY
1310 1320 1330 1340 1350
ITLLNELDEA VQFSNASYEA AILENLALGT EIVRVQAYSI DNLNQITYRF
1360 1370 1380
DAYTSTQAKA LFKIDAITVR GWGQGAPFLP I
Length:1,381
Mass (Da):152,248
Last modified:July 5, 2004 - v1
Checksum:i364E66F7DF3F752F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC065284 mRNA Translation: AAH65284.1
RefSeqiNP_001165401.1, NM_001171930.1
NP_071407.4, NM_022124.5
UniGeneiHs.656032

Genome annotation databases

GeneIDi64072
KEGGihsa:64072

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC065284 mRNA Translation: AAH65284.1
RefSeqiNP_001165401.1, NM_001171930.1
NP_071407.4, NM_022124.5
UniGeneiHs.656032

3D structure databases

ProteinModelPortaliQ6P152
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiQ6P152
PRIDEiQ6P152

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi64072
KEGGihsa:64072

Organism-specific databases

CTDi64072
PharmGKBiPA26296

Phylogenomic databases

HOGENOMiHOG000139588
HOVERGENiHBG062348
KOiK06813

Miscellaneous databases

ChiTaRSiCDH23 human
GenomeRNAii64072

Gene expression databases

GenevisibleiQ6P152 HS

Family and domain databases

InterProiView protein in InterPro
IPR002126 Cadherin-like_dom
IPR015919 Cadherin-like_sf
IPR020894 Cadherin_CS
IPR033030 CDH23
PANTHERiPTHR43956:SF3 PTHR43956:SF3, 1 hit
PfamiView protein in Pfam
PF00028 Cadherin, 12 hits
PRINTSiPR00205 CADHERIN
SMARTiView protein in SMART
SM00112 CA, 12 hits
SUPFAMiSSF49313 SSF49313, 12 hits
PROSITEiView protein in PROSITE
PS00232 CADHERIN_1, 4 hits
ProtoNetiSearch...

Entry informationi

Entry nameiQ6P152_HUMAN
AccessioniPrimary (citable) accession number: Q6P152
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: November 7, 2018
This is version 87 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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