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UniProtKB - Q6P0X9 (Q6P0X9_DANRE)
Protein
Submitted name:
Origin recognition complex, subunit 5
Gene
orc5
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Functioni
GO - Molecular functioni
- DNA replication origin binding Source: GO_Central
GO - Biological processi
- DNA replication initiation Source: GO_Central
Enzyme and pathway databases
Reactomei | R-DRE-176187, Activation of ATR in response to replication stress R-DRE-68616, Assembly of the ORC complex at the origin of replication R-DRE-68689, CDC6 association with the ORC:origin complex R-DRE-68827, CDT1 association with the CDC6:ORC:origin complex R-DRE-68867, Assembly of the pre-replicative complex R-DRE-68949, Orc1 removal from chromatin R-DRE-68962, Activation of the pre-replicative complex |
Names & Taxonomyi
Protein namesi | Submitted name: Origin recognition complex, subunit 5ImportedSubmitted name: Origin recognition complex, subunit 5-like (Yeast)Imported |
Gene namesi | |
Organismi | Danio rerio (Zebrafish) (Brachydanio rerio)Imported |
Taxonomic identifieri | 7955 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio |
Proteomesi |
|
Organism-specific databases
ZFINi | ZDB-GENE-040426-2275, orc5 |
Subcellular locationi
Nucleus
- Nucleus ARBA annotation
Nucleus
- nuclear origin of replication recognition complex Source: GO_Central
Expressioni
Gene expression databases
Bgeei | ENSDARG00000021579, Expressed in eye and 34 other tissues |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 21 – 164 | AAA_16InterPro annotationAdd BLAST | 144 |
Phylogenomic databases
eggNOGi | KOG2543, Eukaryota |
GeneTreei | ENSGT00390000009380 |
HOGENOMi | CLU_028223_0_1_1 |
OMAi | QLRRWHG |
OrthoDBi | 571556at2759 |
TreeFami | TF101095 |
Family and domain databases
Gene3Di | 3.40.50.300, 1 hit |
InterProi | View protein in InterPro IPR041664, AAA_16 IPR020796, ORC5 IPR027417, P-loop_NTPase |
PANTHERi | PTHR12705, PTHR12705, 1 hit |
Pfami | View protein in Pfam PF13191, AAA_16, 1 hit PF14630, ORC5_C, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
i Sequence
Sequence statusi: Complete.
Q6P0X9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPVTLQCPGY PEDTLRTLAE KLPCRETQVT SLLSLMGQPD HYSYPSVFIY
60 70 80 90 100
GHRATGKSHV VLTIMKDLEL PHASVDCVEC VSAGLLFYQV LSALFGPDSA
110 120 130 140 150
ALLPRCPSLS DFVRLYKQMS SNTPATQTRY IVLDRAERIR DMDFSLLPAL
160 170 180 190 200
LRLQELVNDN VTIILLSEIV WEKFRPNTGC FEPLLFHFPD YSKVELVQIL
210 220 230 240 250
SKDHHPSYTP ELYASYINIL LGVFFSVCRD LRELRHLAML NFSKFCEPLE
260 270 280 290 300
KGEAKESDIH KLWKNIEPHL HRAMQTVYLR EVSSVQWEQQ QMDEKEATAL
310 320 330 340 350
RGLSAHAHIE LPYYSKFLLI AAYLASFNPA RTDRRFFLKS HGKIKKTNFL
360 370 380 390 400
KKHEKTSNHL LGPKPFPLDR LLAIFYSVVD SRVAPTASIF SQISSLVTLQ
410 420 430 440
LLSQVGHDDQ LDSPKYKCAV SLDFILAISR TVSFDVVKYL YDFL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX537162 Genomic DNA No translation available. BC065383 mRNA Translation: AAH65383.1 |
RefSeqi | NP_998363.1, NM_213198.1 XP_017210478.1, XM_017354989.1 XP_017210479.1, XM_017354990.1 XP_017210480.1, XM_017354991.1 |
Genome annotation databases
Ensembli | ENSDART00000037670; ENSDARP00000033056; ENSDARG00000021579 |
GeneIDi | 406479 |
KEGGi | dre:406479 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX537162 Genomic DNA No translation available. BC065383 mRNA Translation: AAH65383.1 |
RefSeqi | NP_998363.1, NM_213198.1 XP_017210478.1, XM_017354989.1 XP_017210479.1, XM_017354990.1 XP_017210480.1, XM_017354991.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 7955.ENSDARP00000033056 |
Genome annotation databases
Ensembli | ENSDART00000037670; ENSDARP00000033056; ENSDARG00000021579 |
GeneIDi | 406479 |
KEGGi | dre:406479 |
Organism-specific databases
CTDi | 5001 |
ZFINi | ZDB-GENE-040426-2275, orc5 |
Phylogenomic databases
eggNOGi | KOG2543, Eukaryota |
GeneTreei | ENSGT00390000009380 |
HOGENOMi | CLU_028223_0_1_1 |
OMAi | QLRRWHG |
OrthoDBi | 571556at2759 |
TreeFami | TF101095 |
Enzyme and pathway databases
Reactomei | R-DRE-176187, Activation of ATR in response to replication stress R-DRE-68616, Assembly of the ORC complex at the origin of replication R-DRE-68689, CDC6 association with the ORC:origin complex R-DRE-68827, CDT1 association with the CDC6:ORC:origin complex R-DRE-68867, Assembly of the pre-replicative complex R-DRE-68949, Orc1 removal from chromatin R-DRE-68962, Activation of the pre-replicative complex |
Gene expression databases
Bgeei | ENSDARG00000021579, Expressed in eye and 34 other tissues |
Family and domain databases
Gene3Di | 3.40.50.300, 1 hit |
InterProi | View protein in InterPro IPR041664, AAA_16 IPR020796, ORC5 IPR027417, P-loop_NTPase |
PANTHERi | PTHR12705, PTHR12705, 1 hit |
Pfami | View protein in Pfam PF13191, AAA_16, 1 hit PF14630, ORC5_C, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Q6P0X9_DANRE | |
Accessioni | Q6P0X9Primary (citable) accession number: Q6P0X9 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 5, 2004 |
Last sequence update: | July 5, 2004 | |
Last modified: | January 19, 2022 | |
This is version 112 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |