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Protein

Microtubule-associated serine/threonine-protein kinase 2

Gene

MAST2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins. Functions in a multi-protein complex in spermatid maturation. Regulates lipopolysaccharide-induced IL-12 synthesis in macrophages by forming a complex with TRAF6, resulting in the inhibition of TRAF6 NF-kappa-B activation (By similarity).By similarity

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.By similarity

Cofactori

Mg2+By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei541ATPPROSITE-ProRule annotationBy similarity1
Active sitei635Proton acceptorPROSITE-ProRule annotationBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi518 – 526ATPPROSITE-ProRule annotationBy similarity9

GO - Molecular functioni

  • ATP binding Source: UniProtKB
  • magnesium ion binding Source: UniProtKB
  • microtubule binding Source: GO_Central
  • phosphatase binding Source: UniProtKB
  • protein serine/threonine kinase activity Source: GO_Central

GO - Biological processi

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinase, Transferase
LigandATP-binding, Magnesium, Metal-binding, Nucleotide-binding

Enzyme and pathway databases

SignaLinkiQ6P0Q8
SIGNORiQ6P0Q8

Names & Taxonomyi

Protein namesi
Recommended name:
Microtubule-associated serine/threonine-protein kinase 2 (EC:2.7.11.1)
Gene namesi
Name:MAST2Imported
Synonyms:KIAA0807Imported, MAST205Imported
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000086015.20
HGNCiHGNC:19035 MAST2
MIMi612257 gene
neXtProtiNX_Q6P0Q8

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell membrane, Cytoplasm, Cytoskeleton, Membrane

Pathology & Biotechi

Organism-specific databases

DisGeNETi23139
OpenTargetsiENSG00000086015
PharmGKBiPA134954073

Chemistry databases

ChEMBLiCHEMBL3038500

Polymorphism and mutation databases

BioMutaiMAST2
DMDMi62287152

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000863121 – 1798Microtubule-associated serine/threonine-protein kinase 2Add BLAST1798

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei66PhosphoserineCombined sources1
Modified residuei74PhosphoserineCombined sources1
Modified residuei148PhosphoserineCombined sources1
Modified residuei151PhosphoserineBy similarity1
Modified residuei209PhosphoserineCombined sources1
Modified residuei290PhosphoserineCombined sources1
Modified residuei874PhosphoserineCombined sources1
Modified residuei876PhosphoserineCombined sources1
Modified residuei895PhosphoserineBy similarity1
Modified residuei900PhosphoserineCombined sources1
Modified residuei1004Omega-N-methylarginineCombined sources1
Modified residuei1032PhosphoserineCombined sources1
Modified residuei1256PhosphoserineCombined sources1
Modified residuei1337PhosphoserineBy similarity1
Modified residuei1364PhosphoserineCombined sources1
Modified residuei1447PhosphoserineCombined sources1
Modified residuei1508PhosphothreonineCombined sources1

Post-translational modificationi

Phosphorylated and ubiquitinated. N-terminal ubiquitination leads to degradation of MAST2 by proteasome-mediated proteolysis. N-terminal phosphorylation appears to be a prerequisite for ubiquitination (By similarity).By similarity

Keywords - PTMi

Methylation, Phosphoprotein, Ubl conjugation

Proteomic databases

EPDiQ6P0Q8
MaxQBiQ6P0Q8
PaxDbiQ6P0Q8
PeptideAtlasiQ6P0Q8
PRIDEiQ6P0Q8
ProteomicsDBi66816
66817 [Q6P0Q8-2]

PTM databases

iPTMnetiQ6P0Q8
PhosphoSitePlusiQ6P0Q8

Expressioni

Tissue specificityi

Abundant in the testis.1 Publication

Gene expression databases

BgeeiENSG00000086015 Expressed in 235 organ(s), highest expression level in gastrocnemius
CleanExiHS_MAST2
ExpressionAtlasiQ6P0Q8 baseline and differential
GenevisibleiQ6P0Q8 HS

Organism-specific databases

HPAiHPA039722
HPA040155

Interactioni

Subunit structurei

Interacts with CDHR2.1 Publication

Binary interactionsi

GO - Molecular functioni

Protein-protein interaction databases

BioGridi116756, 21 interactors
ELMiQ6P0Q8
IntActiQ6P0Q8, 18 interactors
MINTiQ6P0Q8
STRINGi9606.ENSP00000354671

Structurei

Secondary structure

11798
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliQ6P0Q8
SMRiQ6P0Q8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini512 – 785Protein kinasePROSITE-ProRule annotationAdd BLAST274
Domaini786 – 854AGC-kinase C-terminalAdd BLAST69
Domaini1104 – 1192PDZPROSITE-ProRule annotationAdd BLAST89

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG0606 Eukaryota
ENOG410XPWX LUCA
GeneTreeiENSGT00530000063286
HOVERGENiHBG052414
InParanoidiQ6P0Q8
KOiK08789
OMAiCCSPPIK
OrthoDBiEOG091G00IH
PhylomeDBiQ6P0Q8
TreeFamiTF313149

Family and domain databases

CDDicd05609 STKc_MAST, 1 hit
Gene3Di1.20.1480.20, 1 hit
InterProiView protein in InterPro
IPR000961 AGC-kinase_C
IPR011009 Kinase-like_dom_sf
IPR015022 MA_Ser/Thr_Kinase_dom
IPR037711 MAST
IPR028779 MAST2
IPR023142 MAST_pre-PK_dom_sf
IPR001478 PDZ
IPR036034 PDZ_sf
IPR000719 Prot_kinase_dom
IPR008271 Ser/Thr_kinase_AS
PANTHERiPTHR24356:SF136 PTHR24356:SF136, 1 hit
PfamiView protein in Pfam
PF08926 DUF1908, 1 hit
PF00595 PDZ, 1 hit
PF00069 Pkinase, 1 hit
SMARTiView protein in SMART
SM00228 PDZ, 1 hit
SM00220 S_TKc, 1 hit
SUPFAMiSSF140482 SSF140482, 1 hit
SSF50156 SSF50156, 1 hit
SSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS51285 AGC_KINASE_CTER, 1 hit
PS50106 PDZ, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit

Sequences (2+)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 11 Publication (identifier: Q6P0Q8-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MKRSRCRDRP QPPPPDRRED GVQRAAELSQ SLPPRRRAPP GRQRLEERTG
60 70 80 90 100
PAGPEGKEQD VVTGVSPLLF RKLSNPDIFS STGKVKLQRQ LSQDDCKLWR
110 120 130 140 150
GNLASSLSGK QLLPLSSSVH SSVGQVTWQS SGEASNLVRM RNQSLGQSAP
160 170 180 190 200
SLTAGLKELS LPRRGSFCRT SNRKSLIVTS STSPTLPRPH SPLHGHTGNS
210 220 230 240 250
PLDSPRNFSP NAPAHFSFVP ARRTDGRRWS LASLPSSGYG TNTPSSTVSS
260 270 280 290 300
SCSSQEKLHQ LPFQPTADEL HFLTKHFSTE SVPDEEGRQS PAMRPRSRSL
310 320 330 340 350
SPGRSPVSFD SEIIMMNHVY KERFPKATAQ MEERLAEFIS SNTPDSVLPL
360 370 380 390 400
ADGALSFIHH QVIEMARDCL DKSRSGLITS QYFYELQDNL EKLLQDAHER
410 420 430 440 450
SESSEVAFVM QLVKKLMIII ARPARLLECL EFDPEEFYHL LEAAEGHAKE
460 470 480 490 500
GQGIKCDIPR YIVSQLGLTR DPLEEMAQLS SCDSPDTPET DDSIEGHGAS
510 520 530 540 550
LPSKKTPSEE DFETIKLISN GAYGAVFLVR HKSTRQRFAM KKINKQNLIL
560 570 580 590 600
RNQIQQAFVE RDILTFAENP FVVSMFCSFD TKRHLCMVME YVEGGDCATL
610 620 630 640 650
LKNIGALPVD MVRLYFAETV LALEYLHNYG IVHRDLKPDN LLITSMGHIK
660 670 680 690 700
LTDFGLSKIG LMSLTTNLYE GHIEKDAREF LDKQVCGTPE YIAPEVILRQ
710 720 730 740 750
GYGKPVDWWA MGIILYEFLV GCVPFFGDTP EELFGQVISD EIVWPEGDEA
760 770 780 790 800
LPPDAQDLTS KLLHQNPLER LGTGSAYEVK QHPFFTGLDW TGLLRQKAEF
810 820 830 840 850
IPQLESEDDT SYFDTRSERY HHMDSEDEEE VSEDGCLEIR QFSSCSPRFN
860 870 880 890 900
KVYSSMERLS LLEERRTPPP TKRSLSEEKE DHSDGLAGLK GRDRSWVIGS
910 920 930 940 950
PEILRKRLSV SESSHTESDS SPPMTVRRRC SGLLDAPRFP EGPEEASSTL
960 970 980 990 1000
RRQPQEGIWV LTPPSGEGVS GPVTEHSGEQ RPKLDEEAVG RSSGSSPAME
1010 1020 1030 1040 1050
TRGRGTSQLA EGATAKAISD LAVRRARHRL LSGDSTEKRT ARPVNKVIKS
1060 1070 1080 1090 1100
ASATALSLLI PSEHHTCSPL ASPMSPHSQS SNPSSRDSSP SRDFLPALGS
1110 1120 1130 1140 1150
MRPPIIIHRA GKKYGFTLRA IRVYMGDSDV YTVHHMVWHV EDGGPASEAG
1160 1170 1180 1190 1200
LRQGDLITHV NGEPVHGLVH TEVVELILKS GNKVAISTTP LENTSIKVGP
1210 1220 1230 1240 1250
ARKGSYKAKM ARRSKRSRGK DGQESRKRSS LFRKITKQAS LLHTSRSLSS
1260 1270 1280 1290 1300
LNRSLSSGES GPGSPTHSHS LSPRSPTQGY RVTPDAVHSV GGNSSQSSSP
1310 1320 1330 1340 1350
SSSVPSSPAG SGHTRPSSLH GLAPKLQRQY RSPRRKSAGS IPLSPLAHTP
1360 1370 1380 1390 1400
SPPPPTASPQ RSPSPLSGHV AQAFPTKLHL SPPLGRQLSR PKSAEPPRSP
1410 1420 1430 1440 1450
LLKRVQSAEK LAAALAASEK KLATSRKHSL DLPHSELKKE LPPREVSPLE
1460 1470 1480 1490 1500
VVGARSVLSG KGALPGKGVL QPAPSRALGT LRQDRAERRE SLQKQEAIRE
1510 1520 1530 1540 1550
VDSSEDDTEE GPENSQGAQE LSLAPHPEVS QSVAPKGAGE SGEEDPFPSR
1560 1570 1580 1590 1600
DPRSLGPMVP SLLTGITLGP PRMESPSGPH RRLGSPQAIE EAASSSSAGP
1610 1620 1630 1640 1650
NLGQSGATDP IPPEGCWKAQ HLHTQALTAL SPSTSGLTPT SSCSPPSSTS
1660 1670 1680 1690 1700
GKLSMWSWKS LIEGPDRASP SRKATMAGGL ANLQDLENTT PAQPKNLSPR
1710 1720 1730 1740 1750
EQGKTQPPSA PRLAHPSYED PSQGWLWESE CAQAVKEDPA LSITQVPDAS
1760 1770 1780 1790
GDRRQDVPCR GCPLTQKSEP SLRRGQEPGG HQKHRDLALV PDELLKQT
Length:1,798
Mass (Da):196,436
Last modified:March 29, 2005 - v2
Checksum:iDF5C92078A3451AF
GO
Isoform 2Curated (identifier: Q6P0Q8-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     327-396: Missing.
     1091-1113: Missing.
     1290-1386: Missing.

Note: No experimental confirmation available.Curated
Show »
Length:1,608
Mass (Da):176,132
Checksum:iE8E7D89D72A99168
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E7ERL6E7ERL6_HUMAN
Microtubule-associated serine/threo...
MAST2
791Annotation score:
V9GXZ1V9GXZ1_HUMAN
Microtubule-associated serine/threo...
MAST2
787Annotation score:

Sequence cautioni

The sequence AAH15816 differs from that shown. Reason: Frameshift at positions 1114 and 1387.Curated
The sequence AAH15816 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAB40778 differs from that shown. Reason: Frameshift at position 1688.Curated
The sequence CAH73245 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence CAI16563 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence CAI21706 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti1225Missing in AAH65499 (PubMed:15489334).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_04077169L → F1 PublicationCorresponds to variant dbSNP:rs55914403Ensembl.1
Natural variantiVAR_040772275K → E in an ovarian mucinous carcinoma sample; somatic mutation. 1 Publication1
Natural variantiVAR_040773388D → E2 PublicationsCorresponds to variant dbSNP:rs11211247Ensembl.1
Natural variantiVAR_040774655G → A in a breast mucinous carcinoma sample; somatic mutation. 1 Publication1
Natural variantiVAR_040775659I → M4 PublicationsCorresponds to variant dbSNP:rs1707336Ensembl.1
Natural variantiVAR_040776991R → L1 PublicationCorresponds to variant dbSNP:rs56114653Ensembl.1
Natural variantiVAR_0407771197K → R1 PublicationCorresponds to variant dbSNP:rs1052607Ensembl.1
Natural variantiVAR_0407781221D → E1 PublicationCorresponds to variant dbSNP:rs56060730Ensembl.1
Natural variantiVAR_0407791246R → L1 PublicationCorresponds to variant dbSNP:rs56309943Ensembl.1
Natural variantiVAR_0407801304V → M1 PublicationCorresponds to variant dbSNP:rs33931638Ensembl.1
Natural variantiVAR_0407811463A → T1 PublicationCorresponds to variant dbSNP:rs3737738Ensembl.1
Natural variantiVAR_0407821468G → A1 PublicationCorresponds to variant dbSNP:rs3737737Ensembl.1
Natural variantiVAR_0407831551D → G3 PublicationsCorresponds to variant dbSNP:rs1052610Ensembl.1
Natural variantiVAR_0516451608T → I. Corresponds to variant dbSNP:rs35474583Ensembl.1
Natural variantiVAR_0407841673K → R1 PublicationCorresponds to variant dbSNP:rs34070850Ensembl.1
Natural variantiVAR_0407851703G → E1 Publication1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_051698327 – 396Missing in isoform 2. 1 PublicationAdd BLAST70
Alternative sequenceiVSP_0516991091 – 1113Missing in isoform 2. 1 PublicationAdd BLAST23
Alternative sequenceiVSP_0517001290 – 1386Missing in isoform 2. 1 PublicationAdd BLAST97

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB047005 mRNA Translation: BAB40778.1 Frameshift.
AL645480
, AL358075, AL603882, AL603888 Genomic DNA Translation: CAH73244.1
AL645480, AL358075, AL603888 Genomic DNA Translation: CAH73245.1 Sequence problems.
AL603882
, AL358075, AL603888, AL645480 Genomic DNA Translation: CAI16217.1
AL603888
, AL358075, AL603882, AL645480 Genomic DNA Translation: CAI16562.1
AL603888, AL358075, AL645480 Genomic DNA Translation: CAI16563.1 Sequence problems.
AL358075
, AL603882, AL603888, AL645480 Genomic DNA Translation: CAI21705.1
AL358075, AL603888, AL645480 Genomic DNA Translation: CAI21706.1 Sequence problems.
BC015816 mRNA Translation: AAH15816.2 Different initiation.
BC065499 mRNA Translation: AAH65499.1
AB018350 mRNA Translation: BAA34527.2
AL833919 mRNA Translation: CAD38775.1
CCDSiCCDS41326.1 [Q6P0Q8-1]
RefSeqiNP_001306174.1, NM_001319245.1
NP_055927.2, NM_015112.2 [Q6P0Q8-1]
UniGeneiHs.319481

Genome annotation databases

EnsembliENST00000361297; ENSP00000354671; ENSG00000086015 [Q6P0Q8-1]
GeneIDi23139
KEGGihsa:23139
UCSCiuc001cov.3 human [Q6P0Q8-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB047005 mRNA Translation: BAB40778.1 Frameshift.
AL645480
, AL358075, AL603882, AL603888 Genomic DNA Translation: CAH73244.1
AL645480, AL358075, AL603888 Genomic DNA Translation: CAH73245.1 Sequence problems.
AL603882
, AL358075, AL603888, AL645480 Genomic DNA Translation: CAI16217.1
AL603888
, AL358075, AL603882, AL645480 Genomic DNA Translation: CAI16562.1
AL603888, AL358075, AL645480 Genomic DNA Translation: CAI16563.1 Sequence problems.
AL358075
, AL603882, AL603888, AL645480 Genomic DNA Translation: CAI21705.1
AL358075, AL603888, AL645480 Genomic DNA Translation: CAI21706.1 Sequence problems.
BC015816 mRNA Translation: AAH15816.2 Different initiation.
BC065499 mRNA Translation: AAH65499.1
AB018350 mRNA Translation: BAA34527.2
AL833919 mRNA Translation: CAD38775.1
CCDSiCCDS41326.1 [Q6P0Q8-1]
RefSeqiNP_001306174.1, NM_001319245.1
NP_055927.2, NM_015112.2 [Q6P0Q8-1]
UniGeneiHs.319481

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2KQFNMR-A1099-1193[»]
2KYLNMR-A1099-1193[»]
ProteinModelPortaliQ6P0Q8
SMRiQ6P0Q8
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi116756, 21 interactors
ELMiQ6P0Q8
IntActiQ6P0Q8, 18 interactors
MINTiQ6P0Q8
STRINGi9606.ENSP00000354671

Chemistry databases

ChEMBLiCHEMBL3038500

PTM databases

iPTMnetiQ6P0Q8
PhosphoSitePlusiQ6P0Q8

Polymorphism and mutation databases

BioMutaiMAST2
DMDMi62287152

Proteomic databases

EPDiQ6P0Q8
MaxQBiQ6P0Q8
PaxDbiQ6P0Q8
PeptideAtlasiQ6P0Q8
PRIDEiQ6P0Q8
ProteomicsDBi66816
66817 [Q6P0Q8-2]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000361297; ENSP00000354671; ENSG00000086015 [Q6P0Q8-1]
GeneIDi23139
KEGGihsa:23139
UCSCiuc001cov.3 human [Q6P0Q8-1]

Organism-specific databases

CTDi23139
DisGeNETi23139
EuPathDBiHostDB:ENSG00000086015.20
GeneCardsiMAST2
H-InvDBiHIX0000540
HGNCiHGNC:19035 MAST2
HPAiHPA039722
HPA040155
MIMi612257 gene
neXtProtiNX_Q6P0Q8
OpenTargetsiENSG00000086015
PharmGKBiPA134954073
HUGEiSearch...
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0606 Eukaryota
ENOG410XPWX LUCA
GeneTreeiENSGT00530000063286
HOVERGENiHBG052414
InParanoidiQ6P0Q8
KOiK08789
OMAiCCSPPIK
OrthoDBiEOG091G00IH
PhylomeDBiQ6P0Q8
TreeFamiTF313149

Enzyme and pathway databases

SignaLinkiQ6P0Q8
SIGNORiQ6P0Q8

Miscellaneous databases

ChiTaRSiMAST2 human
GeneWikiiMAST2
GenomeRNAii23139
PROiPR:Q6P0Q8
SOURCEiSearch...

Gene expression databases

BgeeiENSG00000086015 Expressed in 235 organ(s), highest expression level in gastrocnemius
CleanExiHS_MAST2
ExpressionAtlasiQ6P0Q8 baseline and differential
GenevisibleiQ6P0Q8 HS

Family and domain databases

CDDicd05609 STKc_MAST, 1 hit
Gene3Di1.20.1480.20, 1 hit
InterProiView protein in InterPro
IPR000961 AGC-kinase_C
IPR011009 Kinase-like_dom_sf
IPR015022 MA_Ser/Thr_Kinase_dom
IPR037711 MAST
IPR028779 MAST2
IPR023142 MAST_pre-PK_dom_sf
IPR001478 PDZ
IPR036034 PDZ_sf
IPR000719 Prot_kinase_dom
IPR008271 Ser/Thr_kinase_AS
PANTHERiPTHR24356:SF136 PTHR24356:SF136, 1 hit
PfamiView protein in Pfam
PF08926 DUF1908, 1 hit
PF00595 PDZ, 1 hit
PF00069 Pkinase, 1 hit
SMARTiView protein in SMART
SM00228 PDZ, 1 hit
SM00220 S_TKc, 1 hit
SUPFAMiSSF140482 SSF140482, 1 hit
SSF50156 SSF50156, 1 hit
SSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS51285 AGC_KINASE_CTER, 1 hit
PS50106 PDZ, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiMAST2_HUMAN
AccessioniPrimary (citable) accession number: Q6P0Q8
Secondary accession number(s): O94899
, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: March 29, 2005
Last modified: September 12, 2018
This is version 146 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  6. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  7. Human and mouse protein kinases
    Human and mouse protein kinases: classification and index
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