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Protein
Submitted name:

NAD(P)H dehydrogenase, quinone 1

Gene

nqo1

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • electron transfer activity Source: GO_Central
  • NAD(P)H dehydrogenase (quinone) activity Source: GO_Central
  • oxidoreductase activity Source: GO_Central

GO - Biological processi

  • cellular response to xenobiotic stimulus Source: ZFIN

Enzyme and pathway databases

ReactomeiR-DRE-350562 Regulation of ornithine decarboxylase (ODC)

Names & Taxonomyi

Protein namesi
Submitted name:
NAD(P)H dehydrogenase, quinone 1Imported
Gene namesi
Name:nqo1Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 7

Organism-specific databases

ZFINiZDB-GENE-030131-1226 nqo1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSDARG00000010250 Expressed in 29 organ(s), highest expression level in multi-cellular organism

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 211Flavodoxin_2InterPro annotationAdd BLAST207

Phylogenomic databases

eggNOGiENOG410IKWF Eukaryota
COG2249 LUCA
GeneTreeiENSGT00440000033410
HOGENOMiHOG000149970
HOVERGENiHBG029104
TreeFamiTF300296

Family and domain databases

Gene3Di3.40.50.360, 1 hit
InterProiView protein in InterPro
IPR003680 Flavodoxin_fold
IPR029039 Flavoprotein-like_sf
PfamiView protein in Pfam
PF02525 Flavodoxin_2, 1 hit
SUPFAMiSSF52218 SSF52218, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

Q6P0H2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAQKTALIVY AHQSPASFNA AARDVAVQAL TKKGYKVLVS DLYAMKFKAS
60 70 80 90 100
ATAEDIKGDL QNPEHFVYNN EMMVAWKEGR LSDDVAEEQH KVEQADLIIF
110 120 130 140 150
QYPLYWFTIP AIMKGWIDRV LTQGFAFSMQ NMYDNGIFKN KRAMLSFTTG
160 170 180 190 200
GMESMYKDDS LHGDINILLW PLQNGVLRFC GFQVLAPQIF WSPAYTPPEG
210 220 230 240 250
RAAMLDGWRE RLGGVFEEKP LSFAPSEYFD LSFQAGFCLR PEVKDKLASE
260 270
PYGITTAHHL GKPLPPNNQT KPKQN
Length:275
Mass (Da):31,090
Last modified:July 5, 2004 - v1
Checksum:iB519AD0EFE14330A
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F1QLV5F1QLV5_DANRE
NAD(P)H dehydrogenase, quinone 1
nqo1
293Annotation score:
A0A2R8PW65A0A2R8PW65_DANRE
NAD(P)H dehydrogenase, quinone 1
nqo1
289Annotation score:
E9QEA9E9QEA9_DANRE
NAD(P)H dehydrogenase, quinone 1
nqo1
185Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX255936 Genomic DNA No translation available.
BC065622 mRNA Translation: AAH65622.1
RefSeqiNP_991105.1, NM_205542.2
UniGeneiDr.4189

Genome annotation databases

EnsembliENSDART00000004964; ENSDARP00000021150; ENSDARG00000010250
GeneIDi322506

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX255936 Genomic DNA No translation available.
BC065622 mRNA Translation: AAH65622.1
RefSeqiNP_991105.1, NM_205542.2
UniGeneiDr.4189

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000004964; ENSDARP00000021150; ENSDARG00000010250
GeneIDi322506

Organism-specific databases

CTDi1728
ZFINiZDB-GENE-030131-1226 nqo1

Phylogenomic databases

eggNOGiENOG410IKWF Eukaryota
COG2249 LUCA
GeneTreeiENSGT00440000033410
HOGENOMiHOG000149970
HOVERGENiHBG029104
TreeFamiTF300296

Enzyme and pathway databases

ReactomeiR-DRE-350562 Regulation of ornithine decarboxylase (ODC)

Gene expression databases

BgeeiENSDARG00000010250 Expressed in 29 organ(s), highest expression level in multi-cellular organism

Family and domain databases

Gene3Di3.40.50.360, 1 hit
InterProiView protein in InterPro
IPR003680 Flavodoxin_fold
IPR029039 Flavoprotein-like_sf
PfamiView protein in Pfam
PF02525 Flavodoxin_2, 1 hit
SUPFAMiSSF52218 SSF52218, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ6P0H2_DANRE
AccessioniPrimary (citable) accession number: Q6P0H2
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: November 7, 2018
This is version 102 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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