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Protein

Solute carrier family 25 member 33

Gene

slc25a33

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Mitochondrial transporter that imports/exports pyrimidine nucleotides into and from mitochondria which participates in dendritic cell endocytosis.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTransport

Names & Taxonomyi

Protein namesi
Recommended name:
Solute carrier family 25 member 33
Gene namesi
ORF Names:zgc:65787
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 23

Organism-specific databases

ZFINiZDB-GENE-040426-2183 slc25a33

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei7 – 27Helical; Name=1Sequence analysisAdd BLAST21
Transmembranei44 – 58Helical; Name=2Sequence analysisAdd BLAST15
Transmembranei114 – 134Helical; Name=3Sequence analysisAdd BLAST21
Transmembranei183 – 203Helical; Name=4Sequence analysisAdd BLAST21
Transmembranei226 – 246Helical; Name=5Sequence analysisAdd BLAST21
Transmembranei291 – 311Helical; Name=6Sequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002917871 – 314Solute carrier family 25 member 33Add BLAST314

Proteomic databases

PaxDbiQ6P036

Expressioni

Gene expression databases

BgeeiENSDARG00000039931

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000058406

Structurei

3D structure databases

ProteinModelPortaliQ6P036
SMRiQ6P036
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati4 – 111Solcar 1Add BLAST108
Repeati119 – 206Solcar 2Add BLAST88
Repeati224 – 308Solcar 3Add BLAST85

Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0757 Eukaryota
ENOG410XS20 LUCA
GeneTreeiENSGT00550000074670
HOGENOMiHOG000188210
HOVERGENiHBG059891
InParanoidiQ6P036
KOiK15116
OMAiTHVAVQF
OrthoDBiEOG091G0BCW
PhylomeDBiQ6P036
TreeFamiTF314220

Family and domain databases

Gene3Di1.50.40.10, 2 hits
InterProiView protein in InterPro
IPR002067 Mit_carrier
IPR018108 Mitochondrial_sb/sol_carrier
IPR023395 Mt_carrier_dom_sf
PfamiView protein in Pfam
PF00153 Mito_carr, 3 hits
PRINTSiPR00926 MITOCARRIER
SUPFAMiSSF103506 SSF103506, 1 hit
PROSITEiView protein in PROSITE
PS50920 SOLCAR, 3 hits

Sequencei

Sequence statusi: Complete.

Q6P036-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQKDTLLHL FAGGCGGTVG AIMTCPLEVL KTRLQSSGLT LRPVFQVQLG
60 70 80 90 100
TLNGAGVIRP GSVTPGLLQV LRSILEKEGP RSLFRGLGPN LVGVAPSRAI
110 120 130 140 150
YFAAYSKSKE TFNGIFVPNS GVVHMSSAGF AAFITNSLMN PIWMVKTRMQ
160 170 180 190 200
LEKKARGEKK MNALQCARYV YKTEGMRGFY RGLTASYAGI SETMICFLIY
210 220 230 240 250
ETLKKYLAQS RFTTPDTDND KGASDFLGLM FAAAFAKGCA SCIAYPHEVI
260 270 280 290 300
RTRLREEGSK YKYFFQTARL VAVEEGYAAF YRGLIPQLIR QIPNTAIVLS
310
TYELIVHLLA EPSK
Length:314
Mass (Da):34,488
Last modified:July 5, 2004 - v1
Checksum:iB17F45B8DC39FBA2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC065854 mRNA Translation: AAH65854.1
BC056716 mRNA Translation: AAH56716.1
RefSeqiNP_998322.1, NM_213157.1
UniGeneiDr.76663

Genome annotation databases

EnsembliENSDART00000058407; ENSDARP00000058406; ENSDARG00000039931
GeneIDi406436
KEGGidre:406436

Similar proteinsi

Entry informationi

Entry nameiS2533_DANRE
AccessioniPrimary (citable) accession number: Q6P036
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: July 5, 2004
Last modified: February 28, 2018
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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