UniProtKB - Q6NZL6 (TONSL_MOUSE)

BLAST

>sp|Q6NZL6|TONSL_MOUSE Tonsoku-like protein OS=Mus musculus OX=10090 GN=Tonsl PE=1 SV=2
MTLEQELRQLSKAKTRAQRNGQLREEAAYCHQLGELLASHGRFKDALEEHQQELHLLESV
QDTLGCAVAHRKIGERLAEMENYSAALKHQHLYLDLAGSLSNHTELQRAWATIGRTHLDI
YDHCQSRDSLLQAQAAFEKSLAIVDEKLEGMLTQRELSEMRTRLYLNLGLTCESLQQTAL
CNNYFKKSIFLAEQNHLYEDLFRARYNLGAIHWRGGQHSQAMRCLEGARECARAMKMRFM
ESECCVLVSQVLQDLGDFLAAKRALKKAYRLGSQKPNQRVTVCQSLKYVLAVIQLQQQLE
EAEGNDLQGAMAICEQLGDLFSKAGDFPKAAEAYQKQLHLAELLNRPDLELAVIHVSLAT
TLGDMKDHRKAVHHYEEELRLRKGNALEEAKTWFNIALSREEAGDAYELLAPCFQKAFCC
AQQAQRFQLQRQILQHLYTVQLKLQPQEARDTEIRLQELSMAKDTEEEEEEEEEEEEEAS
EAPETSELELSESEDDADGLSQQLEEDEELQGCVGRRKVNKWNRRNDMGETLLHRACIEG
QLRRVQDLVKQGHPLNPRDYCGWTPLHEACNYGHLEIVRFLLDHGAAVDDPGGQGCDGIT
PLHDALNCGHFEVAELLIERGASVTLRTRKGLSPLETLQQWVKLYFRDLDLETRQKAATM
EERLQMASSGQASRSSPALQTIPSNHLFDPETSPPSSPCPEPSSYTPRPPEASPAPAKVF
LEETVSAVSRPRKTRHRPTSSSSSSEDEDNPSPCRPSQKRLRHTTQQGEVKIPDPPKSRE
TATSSACRAAYQAAIRGVGSAQSRRLVPSLPRGSEEVPAPKTALIPEEEYLAGEWLEVDT
PLTRSGRPSTSVSDYERCPARPRTRVKQSRLTSLDGWCARTQAGDGSLNAEPAENPSVPR
TSGPNKENYAAGQPLLLVQPPPIRVRVQIQDNLFLIPVPQSDIRPVAWLTEQAAQRYFQT
CGLLPRLTLRKDGALLAPQDPIPDVLQSNDEVLAEVTSWDLPPLKDRYRRACLSLGQGEH
QQVLHAMDHQSSSPSFSACSLALCQAQLTPLLRALKLHTALRELRLAGNRLGDACATELL
ATLGTTPNLVLLDLSSNHLGQEGLRQLVEGSSGQAALQNLEELDLSMNPLGDGCGQALAS
LLRACPMLSTLRLQACGFSSSFFLSHQAALGGAFQDAVHLKTLSLSYNLLGAPALARVLQ
TLPACTLKRLDLSSVAASKSNSGIIEPVIKYLTKEGCALAHLTLSANCLGDKAVRELSRC
LPCCPSLTSLDLSANPEVSCASLEELLSALQERSQGLSFLGLSGCSIQGPLNSDLWDKIF
VQLQELQLCTKDLSTKDRDSVCQRLPEGACTMDQSSKLFFKCL

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History
Entry version 127 (28 Feb 2018)
Sequence version 2 (08 Apr 2008)
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Protein

Tonsoku-like protein

Gene

Tonsl

Organism

Mus musculus (Mouse)

Status

Reviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

Component of the MMS22L-TONSL complex, a complex that stimulates the recombination-dependent repair of stalled or collapsed replication forks. The MMS22L-TONSL complex is required to maintain genome integrity during DNA replication by promoting homologous recombination-mediated repair of replication fork-associated double-strand breaks. It may act by mediating the assembly of RAD51 filaments on ssDNA. Within the complex, may act as a scaffold (By similarity).By similarity

GO - Molecular functionⁱ

histone binding Source: UniProtKB

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

double-strand break repair via homologous recombination Source: UniProtKB
replication fork processing Source: UniProtKB

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Biological process	DNA damage, DNA repair

Biological process

DNA damage, DNA repair

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Tonsoku-like protein Alternative name(s): Inhibitor of kappa B-related protein Short name: I-kappa-B-related protein Short name: IkappaBR NF-kappa-B inhibitor-like protein 2 Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2
Gene namesⁱ	Name:Tonsl Synonyms:Ikbr, Nfkbil2
Organismⁱ	Mus musculus (Mouse)
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Unplaced

Organism-specific databases

MGIⁱ	MGI:1919999 Tonsl

Keywords - Cellular componentⁱ

Cytoplasm, Nucleus

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000326635	1 – 1363	Tonsoku-like proteinAdd BLAST		1363

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Modified residueⁱ	796	Omega-N-methylarginineCombined sources		1

Keywords - PTMⁱ

Methylation

Proteomic databases

EPDⁱ	Q6NZL6
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q6NZL6
PaxDbⁱ	Q6NZL6
PeptideAtlas More...PeptideAtlasⁱ	Q6NZL6
PRIDEⁱ	Q6NZL6

PTM databases

iPTMnetⁱ	Q6NZL6
PhosphoSitePlusⁱ	Q6NZL6

Interactionⁱ

Subunit structureⁱ

Component of the MMS22L-TONSL complex, a complex at least composed of MMS22L and TONSL/NFKBIL2. Interacts with the MCM complex, the FACT complex and the RPA complex. Binds histones (By similarity).By similarity

GO - Molecular functionⁱ

histone binding Source: UniProtKB

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

STRINGⁱ	10090.ENSMUSP00000129597

STRINGⁱ

10090.ENSMUSP00000129597

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q6NZL6
SMRⁱ	Q6NZL6
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Repeatⁱ	27 – 60	TPR 1Add BLAST	34
Repeatⁱ	67 – 100	TPR 2Add BLAST	34
Repeatⁱ	107 – 147	TPR 3Add BLAST	41
Repeatⁱ	162 – 195	TPR 4Add BLAST	34
Repeatⁱ	202 – 235	TPR 5Add BLAST	34
Repeatⁱ	242 – 275	TPR 6Add BLAST	34
Repeatⁱ	311 – 344	TPR 7Add BLAST	34
Repeatⁱ	352 – 385	TPR 8Add BLAST	34
Repeatⁱ	528 – 557	ANK 1Add BLAST	30
Repeatⁱ	561 – 590	ANK 2Add BLAST	30
Repeatⁱ	597 – 626	ANK 3Add BLAST	30
Repeatⁱ	1060 – 1081	LRR 1Add BLAST	22
Repeatⁱ	1088 – 1108	LRR 2Add BLAST	21
Repeatⁱ	1119 – 1140	LRR 3Add BLAST	22
Repeatⁱ	1147 – 1168	LRR 4Add BLAST	22
Repeatⁱ	1179 – 1199	LRR 5Add BLAST	21
Repeatⁱ	1206 – 1214	LRR 6	9
Repeatⁱ	1238 – 1261	LRR 7Add BLAST	24
Repeatⁱ	1266 – 1287	LRR 8Add BLAST	22
Repeatⁱ	1296 – 1317	LRR 9Add BLAST	22
Repeatⁱ	1322 – 1343	LRR 10Add BLAST	22

Compositional bias

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Compositional biasⁱ	466 – 509	Glu-richAdd BLAST		44

Domainⁱ

The ANK repeats mediate the interaction with the MCM complex and histones, while the LRR repeats mediate the interaction with MMS22L.By similarity

Sequence similaritiesⁱ

Belongs to the Tonsoku family.Curated

Keywords - Domainⁱ

ANK repeat, Leucine-rich repeat, Repeat, TPR repeat

Phylogenomic databases

eggNOGⁱ	KOG0504 Eukaryota KOG4308 Eukaryota COG0666 LUCA
HOVERGENⁱ	HBG107999
InParanoidⁱ	Q6NZL6
KEGG Orthology (KO) More...KOⁱ	K09257
PhylomeDBⁱ	Q6NZL6

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00204 ANK, 1 hit
Gene3Dⁱ	1.25.40.10, 2 hits 1.25.40.20, 1 hit 3.80.10.10, 2 hits
InterProⁱ	View protein in InterPro IPR002110 Ankyrin_rpt IPR020683 Ankyrin_rpt-contain_dom IPR036770 Ankyrin_rpt-contain_sf IPR001611 Leu-rich_rpt IPR032675 LRR_dom_sf IPR013026 TPR-contain_dom IPR011990 TPR-like_helical_dom_sf IPR019734 TPR_repeat
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF12796 Ank_2, 1 hit PF13516 LRR_6, 2 hits PF13176 TPR_7, 1 hit
PRINTSⁱ	PR01415 ANKYRIN
SMARTⁱ	View protein in SMART SM00248 ANK, 3 hits SM00028 TPR, 5 hits
SUPFAMⁱ	SSF48403 SSF48403, 1 hit SSF48452 SSF48452, 3 hits
PROSITEⁱ	View protein in PROSITE PS50297 ANK_REP_REGION, 1 hit PS50088 ANK_REPEAT, 3 hits PS50293 TPR_REGION, 1 hit

Sequence (1+)ⁱ

Sequence statusⁱ: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show all Align All

Q6NZL6-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MTLEQELRQL SKAKTRAQRN GQLREEAAYC HQLGELLASH GRFKDALEEH 
        60         70         80         90        100
QQELHLLESV QDTLGCAVAH RKIGERLAEM ENYSAALKHQ HLYLDLAGSL 
       110        120        130        140        150
SNHTELQRAW ATIGRTHLDI YDHCQSRDSL LQAQAAFEKS LAIVDEKLEG 
       160        170        180        190        200
MLTQRELSEM RTRLYLNLGL TCESLQQTAL CNNYFKKSIF LAEQNHLYED 
       210        220        230        240        250
LFRARYNLGA IHWRGGQHSQ AMRCLEGARE CARAMKMRFM ESECCVLVSQ 
       260        270        280        290        300
VLQDLGDFLA AKRALKKAYR LGSQKPNQRV TVCQSLKYVL AVIQLQQQLE 
       310        320        330        340        350
EAEGNDLQGA MAICEQLGDL FSKAGDFPKA AEAYQKQLHL AELLNRPDLE 
       360        370        380        390        400
LAVIHVSLAT TLGDMKDHRK AVHHYEEELR LRKGNALEEA KTWFNIALSR 
       410        420        430        440        450
EEAGDAYELL APCFQKAFCC AQQAQRFQLQ RQILQHLYTV QLKLQPQEAR 
       460        470        480        490        500
DTEIRLQELS MAKDTEEEEE EEEEEEEEAS EAPETSELEL SESEDDADGL 
       510        520        530        540        550
SQQLEEDEEL QGCVGRRKVN KWNRRNDMGE TLLHRACIEG QLRRVQDLVK 
       560        570        580        590        600
QGHPLNPRDY CGWTPLHEAC NYGHLEIVRF LLDHGAAVDD PGGQGCDGIT 
       610        620        630        640        650
PLHDALNCGH FEVAELLIER GASVTLRTRK GLSPLETLQQ WVKLYFRDLD 
       660        670        680        690        700
LETRQKAATM EERLQMASSG QASRSSPALQ TIPSNHLFDP ETSPPSSPCP 
       710        720        730        740        750
EPSSYTPRPP EASPAPAKVF LEETVSAVSR PRKTRHRPTS SSSSSEDEDN 
       760        770        780        790        800
PSPCRPSQKR LRHTTQQGEV KIPDPPKSRE TATSSACRAA YQAAIRGVGS 
       810        820        830        840        850
AQSRRLVPSL PRGSEEVPAP KTALIPEEEY LAGEWLEVDT PLTRSGRPST 
       860        870        880        890        900
SVSDYERCPA RPRTRVKQSR LTSLDGWCAR TQAGDGSLNA EPAENPSVPR 
       910        920        930        940        950
TSGPNKENYA AGQPLLLVQP PPIRVRVQIQ DNLFLIPVPQ SDIRPVAWLT 
       960        970        980        990       1000
EQAAQRYFQT CGLLPRLTLR KDGALLAPQD PIPDVLQSND EVLAEVTSWD 
      1010       1020       1030       1040       1050
LPPLKDRYRR ACLSLGQGEH QQVLHAMDHQ SSSPSFSACS LALCQAQLTP 
      1060       1070       1080       1090       1100
LLRALKLHTA LRELRLAGNR LGDACATELL ATLGTTPNLV LLDLSSNHLG 
      1110       1120       1130       1140       1150
QEGLRQLVEG SSGQAALQNL EELDLSMNPL GDGCGQALAS LLRACPMLST 
      1160       1170       1180       1190       1200
LRLQACGFSS SFFLSHQAAL GGAFQDAVHL KTLSLSYNLL GAPALARVLQ 
      1210       1220       1230       1240       1250
TLPACTLKRL DLSSVAASKS NSGIIEPVIK YLTKEGCALA HLTLSANCLG 
      1260       1270       1280       1290       1300
DKAVRELSRC LPCCPSLTSL DLSANPEVSC ASLEELLSAL QERSQGLSFL 
      1310       1320       1330       1340       1350
GLSGCSIQGP LNSDLWDKIF VQLQELQLCT KDLSTKDRDS VCQRLPEGAC 
      1360 
TMDQSSKLFF KCL

Length:1,363

Mass (Da):151,108

Last modified:April 8, 2008 - v2

Checksum:ⁱ7216519012C69DB2

Computationally mapped potential isoform sequencesⁱ

There are 4 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

G3UW83	G3UW83_MOUSE	Nuclear factor of kappa light polyp... Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2 (Tonsoku-like protein)	Tonsl Nfkbil2, mCG_134454	1,363	Annotation score:
E9Q2M2	E9Q2M2_MOUSE	Tonsoku-like protein Tonsoku-like protein	Tonsl	417	Annotation score:
F7A0T4	F7A0T4_MOUSE	Tonsoku-like protein Tonsoku-like protein	Tonsl	86	Annotation score:
E9PZL7	E9PZL7_MOUSE	Tonsoku-like protein Tonsoku-like protein	Tonsl	64	Annotation score:

Sequence cautionⁱ

The sequence AAH66068 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

The sequence BAC25399 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

The sequence CAC08218 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	293 – 294	IQ → NR in CAC08218 (Ref. 3) Curated		2
Sequence conflictⁱ	1106 – 1107	QL → HV in BAC25399 (PubMed:16141072).Curated		2

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC156550 Genomic DNA No translation available. AC157566 Genomic DNA No translation available. BC066068 mRNA Translation: AAH66068.1 Different initiation. AJ294539 Genomic DNA Translation: CAC08218.1 Sequence problems. AK013272 mRNA Translation: BAC25399.1 Different initiation.
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS27580.2
NCBI Reference Sequences More...RefSeqⁱ	NP_898914.3, NM_183091.3
UniGeneⁱ	Mm.358749

Genome annotation databases

GeneIDⁱ	72749
KEGGⁱ	mmu:72749

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q6NZL6	Tonsoku-like protein (Fragment)		MOUSE		64	UniRef100_Q6NZL6

Protein	Similar proteins		Species	Score	Length	Source
Q6NZL6	Tonsoku-like protein		RAT		1367	UniRef90_Q6NZL6
Tonsoku-like protein (Fragment)		MOUSE		64
UPI000A30E042		MUSPA		1364
UPI000A315674		MUSCR		1363
Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2		MOUSE		1363
+4

Protein	Similar proteins		Species	Score	Length	Source
Q6NZL6	Tonsoku-like protein	)	HUMAN		1378	UniRef50_Q96HA7
Tonsoku-like protein		BOVIN		1374
Tonsoku-like protein		RAT		1367
Uncharacterized protein		PANTR		1427
Tonsoku like, DNA repair protein		GORGO		1414
+219

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC156550 Genomic DNA No translation available. AC157566 Genomic DNA No translation available. BC066068 mRNA Translation: AAH66068.1 Different initiation. AJ294539 Genomic DNA Translation: CAC08218.1 Sequence problems. AK013272 mRNA Translation: BAC25399.1 Different initiation.
CCDSⁱ	CCDS27580.2
RefSeqⁱ	NP_898914.3, NM_183091.3
UniGeneⁱ	Mm.358749

3D structure databases

ProteinModelPortalⁱ	Q6NZL6
SMRⁱ	Q6NZL6
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	10090.ENSMUSP00000129597

STRINGⁱ

10090.ENSMUSP00000129597

PTM databases

iPTMnetⁱ	Q6NZL6
PhosphoSitePlusⁱ	Q6NZL6

Proteomic databases

EPDⁱ	Q6NZL6
MaxQBⁱ	Q6NZL6
PaxDbⁱ	Q6NZL6
PeptideAtlasⁱ	Q6NZL6
PRIDEⁱ	Q6NZL6

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

GeneIDⁱ	72749
KEGGⁱ	mmu:72749

Organism-specific databases

CTDⁱ	4796
MGIⁱ	MGI:1919999 Tonsl

Phylogenomic databases

eggNOGⁱ	KOG0504 Eukaryota KOG4308 Eukaryota COG0666 LUCA
HOVERGENⁱ	HBG107999
InParanoidⁱ	Q6NZL6
KOⁱ	K09257
PhylomeDBⁱ	Q6NZL6

Miscellaneous databases

Protein Ontology More...PROⁱ	PR:Q6NZL6
SOURCEⁱ	Search...

Family and domain databases

CDDⁱ	cd00204 ANK, 1 hit
Gene3Dⁱ	1.25.40.10, 2 hits 1.25.40.20, 1 hit 3.80.10.10, 2 hits
InterProⁱ	View protein in InterPro IPR002110 Ankyrin_rpt IPR020683 Ankyrin_rpt-contain_dom IPR036770 Ankyrin_rpt-contain_sf IPR001611 Leu-rich_rpt IPR032675 LRR_dom_sf IPR013026 TPR-contain_dom IPR011990 TPR-like_helical_dom_sf IPR019734 TPR_repeat
Pfamⁱ	View protein in Pfam PF12796 Ank_2, 1 hit PF13516 LRR_6, 2 hits PF13176 TPR_7, 1 hit
PRINTSⁱ	PR01415 ANKYRIN
SMARTⁱ	View protein in SMART SM00248 ANK, 3 hits SM00028 TPR, 5 hits
SUPFAMⁱ	SSF48403 SSF48403, 1 hit SSF48452 SSF48452, 3 hits
PROSITEⁱ	View protein in PROSITE PS50297 ANK_REP_REGION, 1 hit PS50088 ANK_REPEAT, 3 hits PS50293 TPR_REGION, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	TONSL_MOUSE
Accessionⁱ	Q6NZL6Primary (citable) accession number: Q6NZL6 Secondary accession number(s): Q8BT74, Q9ER45
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	April 8, 2008
	Last sequence update:	April 8, 2008
	Last modified:	February 28, 2018
	This is version 127 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q6NZL6 (TONSL_MOUSE)

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Tonsoku-like protein

Tonsl

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Other locations

Nucleus

Other locations

Keywords - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Compositional bias

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Sequence cautionⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ