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Protein

Protein SOGA3

Gene

Soga3

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Protein SOGA3
Gene namesi
Name:Soga3
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 10

Organism-specific databases

MGIiMGI:1914662 Soga3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei913 – 933HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25Sequence analysisAdd BLAST25
ChainiPRO_000027135326 – 945Protein SOGA3Add BLAST920

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei567PhosphoserineCombined sources1
Modified residuei779PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ6NZL0
PaxDbiQ6NZL0
PeptideAtlasiQ6NZL0
PRIDEiQ6NZL0

PTM databases

iPTMnetiQ6NZL0
PhosphoSitePlusiQ6NZL0

Expressioni

Gene expression databases

BgeeiENSMUSG00000038916 Expressed in 130 organ(s), highest expression level in embryo
CleanExiMM_6330407J23RIK
ExpressionAtlasiQ6NZL0 baseline and differential
GenevisibleiQ6NZL0 MM

Interactioni

Protein-protein interaction databases

BioGridi212169, 6 interactors
IntActiQ6NZL0, 7 interactors
STRINGi10090.ENSMUSP00000090293

Structurei

3D structure databases

ProteinModelPortaliQ6NZL0
SMRiQ6NZL0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili340 – 724Sequence analysisAdd BLAST385
Coiled coili809 – 833Sequence analysisAdd BLAST25

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi72 – 81Poly-Gln10
Compositional biasi82 – 246Gly-richAdd BLAST165
Compositional biasi268 – 275Poly-Ala8

Sequence similaritiesi

Belongs to the SOGA family.Curated

Keywords - Domaini

Coiled coil, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG4787 Eukaryota
ENOG410XUHJ LUCA
GeneTreeiENSGT00530000063889
HOGENOMiHOG000111576
HOVERGENiHBG081115
InParanoidiQ6NZL0
OMAiKSGGHES
OrthoDBiEOG091G03VQ
PhylomeDBiQ6NZL0
TreeFamiTF331853

Family and domain databases

InterProiView protein in InterPro
IPR027881 SOGA
PfamiView protein in Pfam
PF11365 SOGA, 2 hits

Sequence (1+)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q6NZL0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSQPPSGGAA PAATSASAAA AATEARMHPE GCSRKQQRAQ SPARPRDNSL
60 70 80 90 100
RQTAGATRSP LGVGPKLNSV RQQQLQQQQQ QGNKITGRST SGTGSRGLGG
110 120 130 140 150
GAEKAVPSIP KGAVPGAVQP APGAEGSPAA ILASVSFRRS GQPEEAPREI
160 170 180 190 200
ESGPSKVGEP PPLGGVGGGG EGGGAGGGPG DREGGAPQPP PPRGWRGKGV
210 220 230 240 250
RATQRGSSVA EGVSPSPPTA ATSKTPGPGS RNSGSGSTGS GSGGGGSYWK
260 270 280 290 300
EGCLQSELIQ FHLKKERAAA AAAAAQMHTK NGGGGSRSSP VAGAPAICEP
310 320 330 340 350
LVVPSSSPMA AAAEGPQQSA EGNGSGGAMQ AAAPPSSQPH SQQLQEQEDM
360 370 380 390 400
QEEMEKLREE NETLKNEIDE LRTEMDEMRD TFFEEDACQL QEMRHELERA
410 420 430 440 450
NKNCRILQYR LRKAERKRLR YAQTGEIDGE LLRSLEQDLK VAKDVSVRLH
460 470 480 490 500
HELENVEEKR TTTEDENEKL RQQLIEVEIA KQALQNELEK MKELSLKRRG
510 520 530 540 550
SKDLPKSEKK AQQTPTEDDN EDLKCQLQFV KEEAALMRKK MAKIDKEKDR
560 570 580 590 600
FEHELQKYRS FYGDLDSPLP KGEAGGPPST REAELKLRLR LVEEEANILG
610 620 630 640 650
RKIVELEVEN RGLKAELDDL RGEDFNGSSN PLMREQSESL SELRQHLQLV
660 670 680 690 700
EDETELLRRN VADLEEQNKR ITAELNKYKY KSSGHDSSRH HDNAKTEALQ
710 720 730 740 750
EELKAARLQI NELSGKVMQL QYENRVLMSN MQRYDLASHL GIRGSPRDSD
760 770 780 790 800
AESDAGKKES DDDSRPPHRK REGPIGGESD SEEVRNIRSL TPTRSFYPTP
810 820 830 840 850
GPWPKSFSDR QQMKDIRSEA ERLGKTIDRL IADTSTIITE ARIYVANGDL
860 870 880 890 900
FGLMDEEDDG SRIREHELLY RINAQMKAFR KELQTFIDRL EVPKSADDRG
910 920 930 940
AEEPISVSQM FQPIILLILI LVLFSSLSYT TIFKLVFLFT LFFVL
Length:945
Mass (Da):103,480
Last modified:January 9, 2007 - v2
Checksum:iDBF08203CDAA4182
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1L1SUV1A0A1L1SUV1_MOUSE
Protein SOGA3
Soga3
199Annotation score:
A0A1L1SR37A0A1L1SR37_MOUSE
Protein SOGA3
Soga3
77Annotation score:

Sequence cautioni

The sequence BAC31794 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti719Q → K in BAB31090 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC092095 Genomic DNA No translation available.
AC153912 Genomic DNA No translation available.
BC066079 mRNA Translation: AAH66079.1 Different termination.
AK012378 mRNA Translation: BAB28200.1
AK018139 mRNA Translation: BAB31090.1
AK044134 mRNA Translation: BAC31794.2 Different initiation.
CCDSiCCDS35875.1
RefSeqiNP_080414.2, NM_026138.2
UniGeneiMm.390264

Genome annotation databases

EnsembliENSMUST00000092629; ENSMUSP00000090293; ENSMUSG00000038916
GeneIDi67412
KEGGimmu:67412
UCSCiuc007est.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC092095 Genomic DNA No translation available.
AC153912 Genomic DNA No translation available.
BC066079 mRNA Translation: AAH66079.1 Different termination.
AK012378 mRNA Translation: BAB28200.1
AK018139 mRNA Translation: BAB31090.1
AK044134 mRNA Translation: BAC31794.2 Different initiation.
CCDSiCCDS35875.1
RefSeqiNP_080414.2, NM_026138.2
UniGeneiMm.390264

3D structure databases

ProteinModelPortaliQ6NZL0
SMRiQ6NZL0
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi212169, 6 interactors
IntActiQ6NZL0, 7 interactors
STRINGi10090.ENSMUSP00000090293

PTM databases

iPTMnetiQ6NZL0
PhosphoSitePlusiQ6NZL0

Proteomic databases

MaxQBiQ6NZL0
PaxDbiQ6NZL0
PeptideAtlasiQ6NZL0
PRIDEiQ6NZL0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000092629; ENSMUSP00000090293; ENSMUSG00000038916
GeneIDi67412
KEGGimmu:67412
UCSCiuc007est.1 mouse

Organism-specific databases

CTDi387104
MGIiMGI:1914662 Soga3

Phylogenomic databases

eggNOGiKOG4787 Eukaryota
ENOG410XUHJ LUCA
GeneTreeiENSGT00530000063889
HOGENOMiHOG000111576
HOVERGENiHBG081115
InParanoidiQ6NZL0
OMAiKSGGHES
OrthoDBiEOG091G03VQ
PhylomeDBiQ6NZL0
TreeFamiTF331853

Miscellaneous databases

PROiPR:Q6NZL0
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000038916 Expressed in 130 organ(s), highest expression level in embryo
CleanExiMM_6330407J23RIK
ExpressionAtlasiQ6NZL0 baseline and differential
GenevisibleiQ6NZL0 MM

Family and domain databases

InterProiView protein in InterPro
IPR027881 SOGA
PfamiView protein in Pfam
PF11365 SOGA, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiSOGA3_MOUSE
AccessioniPrimary (citable) accession number: Q6NZL0
Secondary accession number(s): Q8BLM2, Q9CSN3, Q9CU45
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: January 9, 2007
Last modified: September 12, 2018
This is version 84 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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