UniProtKB - Q6NZH6 (TFCP2_XENTR)
Protein
Transcription factor CP2
Gene
tfcp2
Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Functioni
May function as a transcription factor.
GO - Molecular functioni
- DNA-binding transcription activator activity, RNA polymerase II-specific Source: InterPro
- DNA-binding transcription factor activity Source: GO_Central
- sequence-specific DNA binding Source: GO_Central
GO - Biological processi
- positive regulation of transcription by RNA polymerase II Source: GO_Central
- regulation of transcription by RNA polymerase II Source: GO_Central
Keywordsi
Molecular function | DNA-binding |
Biological process | Transcription, Transcription regulation |
Names & Taxonomyi
Protein namesi | Recommended name: Transcription factor CP2 |
Gene namesi | Name:tfcp2 |
Organismi | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) |
Taxonomic identifieri | 8364 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Amphibia › Batrachia › Anura › Pipoidea › Pipidae › Xenopodinae › Xenopus › Silurana |
Proteomesi |
|
Organism-specific databases
Xenbasei | XB-GENE-485720, tfcp2 |
Subcellular locationi
Keywords - Cellular componenti
NucleusPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000228005 | 1 – 507 | Transcription factor CP2Add BLAST | 507 |
Interactioni
Subunit structurei
Component of the SSP (stage selector protein) complex, which appears to be a heteromer of TFCP2 and 2 copies of NFE4.
By similarityFamily & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 133 – 395 | DNA-bindingBy similarityAdd BLAST | 263 |
Sequence similaritiesi
Phylogenomic databases
GeneTreei | ENSGT00940000157629 |
InParanoidi | Q6NZH6 |
OrthoDBi | 386296at2759 |
Family and domain databases
CDDi | cd09589, SAM_TFCP2, 1 hit |
Gene3Di | 1.10.150.50, 1 hit |
InterProi | View protein in InterPro IPR007604, CP2 IPR013761, SAM/pointed_sf IPR041418, SAM_3 IPR040167, TF_CP2-like IPR037599, TFCP2_SAM |
PANTHERi | PTHR11037, PTHR11037, 1 hit |
Pfami | View protein in Pfam PF04516, CP2, 1 hit PF18016, SAM_3, 1 hit |
SUPFAMi | SSF47769, SSF47769, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All
Q6NZH6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAWALKLPLA DEVIESGLVQ DFDASLSGIG QELGAGAYSM SDVLALPIFK
60 70 80 90 100
QEESSLPSEN ENKILPFQYV LCTATSPAVK LHEETLTYLN QGQSYEIRML
110 120 130 140 150
DNRKMGELPE LNGKLVKSIF RVVFHDRRLQ YTEHQQLEGW RWNRPGDRIL
160 170 180 190 200
DIDIPMSVGI IDPRANPTQL NTVEFLWDPA KRTSVFIQVH CISTEFTMRK
210 220 230 240 250
HGGEKGVPFR VQIDTFKENE NGEYTEHLHS ASCQIKVFKP KGADRKQKTD
260 270 280 290 300
REKMEKRTPQ EKEKYQPSYE TTILTECSPW PEITYVSNAP SPGFNSSHNS
310 320 330 340 350
FPIGEGNGSP NHQPEPPAPI VDVSAGLTPI QNLLPTSTPQ EAQQWLHRNR
360 370 380 390 400
FAAFSRLFTN FSGADLLKLT RDDVIQICGP ADGIRLFNAL KGRMVRPRLT
410 420 430 440 450
IYVCQESQQL REQQQQHKHE NGEAGNSAFY VYHAIYLEEM TAIELTEKIA
460 470 480 490 500
QLFSISPHQI NQIYKQGPTG IHVLISDEMI QNFQDESCFI LDTMKAETND
SYHIILK
Computationally mapped potential isoform sequencesi
There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A6I8RN73 | A0A6I8RN73_XENTR | Transcription factor CP2 | tfcp2 | 384 | Annotation score: | ||
A0A6I8QAB9 | A0A6I8QAB9_XENTR | Transcription factor CP2 | tfcp2 | 516 | Annotation score: | ||
A0A6I8PX88 | A0A6I8PX88_XENTR | Transcription factor CP2 | tfcp2 | 444 | Annotation score: | ||
F7AMR3 | F7AMR3_XENTR | Transcription factor CP2 | tfcp2 | 457 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC066130 mRNA Translation: AAH66130.1 |
RefSeqi | NP_991396.1, NM_205827.1 |
Genome annotation databases
Ensembli | ENSXETT00000085920; ENSXETP00000096781; ENSXETG00000009632 |
GeneIDi | 403094 |
KEGGi | xtr:403094 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC066130 mRNA Translation: AAH66130.1 |
RefSeqi | NP_991396.1, NM_205827.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
Ensembli | ENSXETT00000085920; ENSXETP00000096781; ENSXETG00000009632 |
GeneIDi | 403094 |
KEGGi | xtr:403094 |
Organism-specific databases
CTDi | 7024 |
Xenbasei | XB-GENE-485720, tfcp2 |
Phylogenomic databases
GeneTreei | ENSGT00940000157629 |
InParanoidi | Q6NZH6 |
OrthoDBi | 386296at2759 |
Family and domain databases
CDDi | cd09589, SAM_TFCP2, 1 hit |
Gene3Di | 1.10.150.50, 1 hit |
InterProi | View protein in InterPro IPR007604, CP2 IPR013761, SAM/pointed_sf IPR041418, SAM_3 IPR040167, TF_CP2-like IPR037599, TFCP2_SAM |
PANTHERi | PTHR11037, PTHR11037, 1 hit |
Pfami | View protein in Pfam PF04516, CP2, 1 hit PF18016, SAM_3, 1 hit |
SUPFAMi | SSF47769, SSF47769, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | TFCP2_XENTR | |
Accessioni | Q6NZH6Primary (citable) accession number: Q6NZH6 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | March 21, 2006 |
Last sequence update: | July 5, 2004 | |
Last modified: | December 2, 2020 | |
This is version 82 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families